Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
10 participants
INTERVENTIONAL
2009-06-30
2009-11-30
Brief Summary
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Objective: To study if arterial bevacizumab infusion causes acute vasoconstriction using plethysmography in healthy volunteers.
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
NONE
Study Groups
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Bevacizumab
Bevacizumab
Intra-arterial infusion during 6 minutes
Interventions
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Bevacizumab
Intra-arterial infusion during 6 minutes
Eligibility Criteria
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Inclusion Criteria
* normal results of glucose, lipids and creatinine
* informed consent
Exclusion Criteria
* History of malignant disease
* First degree relatives with a history of cancer before the age of 50
* First degree relatives with a history of premature cardiovascular disease
* Current use of medication
* Clinical evidence of cardiac of pulmonary disease
* Hypertension ( systolic\>140mmHg, diastolic \>90mmHg)
* Diabetes mellitus
* smoking
* a history of thombosis or a family history of recurrent thrombosis
* abnormality on ECG
18 Years
50 Years
MALE
Yes
Sponsors
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Radboud University Medical Center
OTHER
Responsible Party
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UMCN
Principal Investigators
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Gerard Rongen, MD PhD
Role: PRINCIPAL_INVESTIGATOR
UMCN
Locations
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Radboud University Nijmegen Medical Centre
Nijmegen, , Netherlands
Countries
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Other Identifiers
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BVZ1
Identifier Type: -
Identifier Source: org_study_id
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