Emerging Biomarkers in Hypertension

NCT ID: NCT02064218

Last Updated: 2014-02-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Study Classification

OBSERVATIONAL

Study Start Date

2007-11-30

Brief Summary

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First of all to evaluate the relationship between non-conventional biomarkers and essential hypertension; then to evaluate the effects of various anti-hypertensive drugs on blood pressure control and non-conventional biomarkers in naive hypertensive patients

Detailed Description

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Conditions

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Hypertension

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Hypertensive patients

Hypertensive patients naive to hypertensive treatment

Anti-hypertensive drugs

Intervention Type DRUG

healthy subjects

healthy subjects

No interventions assigned to this group

Interventions

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Anti-hypertensive drugs

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* essential hypertension
* naive to treatment
* \< 65 years

Exclusion Criteria

* secondary hypertension
* previous cardiovascular events
Minimum Eligible Age

18 Years

Maximum Eligible Age

64 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Fondazione IRCCS Policlinico San Matteo di Pavia

OTHER

Sponsor Role collaborator

University of Pavia

OTHER

Sponsor Role lead

Responsible Party

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Giuseppe Derosa

MD, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Giuseppe Derosa, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Pavia

Locations

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IRCCS Policlinico S.Matteo Foundation

Pavia, , Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Giuseppe Derosa, MD, PhD

Role: CONTACT

+39 0382 502614

Amedeo Mugellini, MD, PhD

Role: CONTACT

+39 0382 502614

Facility Contacts

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Giuseppe Derosa, MD, PhD

Role: primary

+39 0382 502614

References

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Derosa G, Mugellini A, Pesce RM, D'Angelo A, Maffioli P. Barnidipine compared to lercanidipine in addition to losartan on endothelial damage and oxidative stress parameters in patients with hypertension and type 2 diabetes mellitus. BMC Cardiovasc Disord. 2016 Apr 12;16:66. doi: 10.1186/s12872-016-0237-z.

Reference Type DERIVED
PMID: 27068332 (View on PubMed)

Derosa G, Mugellini A, Pesce RM, D'Angelo A, Maffioli P. Perindopril and barnidipine alone or combined with simvastatin on hepatic steatosis and inflammatory parameters in hypertensive patients. Eur J Pharmacol. 2015 Nov 5;766:31-6. doi: 10.1016/j.ejphar.2015.09.030. Epub 2015 Sep 25.

Reference Type DERIVED
PMID: 26407654 (View on PubMed)

Derosa G, Mugellini A, Querci F, Franzetti I, Pesce RM, D'Angelo A, Maffioli P. Barnidipine or Lercanidipine on Echocardiographic Parameters in Hypertensive, Type 2 Diabetics with Left Ventricular Hypertrophy: A Randomized Clinical Trial. Sci Rep. 2015 Aug 5;5:12603. doi: 10.1038/srep12603.

Reference Type DERIVED
PMID: 26243165 (View on PubMed)

Derosa G, Mugellini A, Pesce RM, D'Angelo A, Maffioli P. A study about the relevance of adding acetylsalicylic acid in primary prevention in subjects with type 2 diabetes mellitus: effects on some new emerging biomarkers of cardiovascular risk. Cardiovasc Diabetol. 2015 Jul 30;14:95. doi: 10.1186/s12933-015-0254-8.

Reference Type DERIVED
PMID: 26223257 (View on PubMed)

Derosa G, Romano D, Bianchi L, D'Angelo A, Maffioli P. The effects of canrenone on inflammatory markers in patients with metabolic syndrome. Ann Med. 2015 Feb;47(1):47-52. doi: 10.3109/07853890.2014.969303. Epub 2014 Oct 16.

Reference Type DERIVED
PMID: 25319120 (View on PubMed)

Other Identifiers

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20070002649

Identifier Type: -

Identifier Source: org_study_id

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