The Effects of Blood Pressure Reduction on Cerebral Perfusion and Cognition in the Elderly Population
NCT ID: NCT00966199
Last Updated: 2009-08-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE4
60 participants
INTERVENTIONAL
2009-09-30
2013-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
SINGLE_GROUP
BASIC_SCIENCE
NONE
Study Groups
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Hypertensive elderly
community dwelling hypertensive elderly from general practices
anti-hypertensive medication
8-12 weeks of anti-hypertensive treatment with 2 weekly titration using registered hypertensive medication
Interventions
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anti-hypertensive medication
8-12 weeks of anti-hypertensive treatment with 2 weekly titration using registered hypertensive medication
Eligibility Criteria
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Inclusion Criteria
* Systolic office blood pressure \>= 160 mmHg
* Systolic home blood pressure \>= 155 mmHg
Exclusion Criteria
* Atrial fibrillation
* Dementia
* Renal failure requiring dialysis
* Life expectancy of less than 1 year
* Disabling stroke
* Contraindication for MRI or anti-hypertensive medication
* Systolic blood pressure \> 220 mmHg
70 Years
ALL
No
Sponsors
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Dutch Heart Foundation
OTHER
Radboud University Medical Center
OTHER
Responsible Party
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Radboud University Nijmegen Medical Centre
Principal Investigators
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Jurgen A Claassen, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Radboud University Medical Center
Locations
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Radboud University
Nijmegen, Gelderland, Netherlands
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2008B113
Identifier Type: -
Identifier Source: secondary_id
MBRACE
Identifier Type: -
Identifier Source: org_study_id
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