Impact of 80 W KTP Laser Vaporization Prostatectomy on Severity of Obstruction in Benign Prostatic Hyperplasia

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

86 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-06-30

Study Completion Date

2007-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to compared the efficacy of 80W KTP photoselective laser vaporization prostatectomy (PVP) and transurethral resection of the prostate (TURP) in reducing the volume of prostate and relieving the obstruction in men with benign prostatic hyperplasia (BPH) on non-randomized controlled design.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

PVP Compared to TURP for the Treatment of Benign Hyperplasia of the Prostate

NCT00527371

Benign Prostatic Hyperplasia

COMPLETED NA

Efficacy Study of HoLEP and TURP on LUTS Secondary to BPH

NCT00877669

Lower Urinary Tract Symptoms Benign Prostatic Hyperplasia

COMPLETED PHASE2

Prognostic Factor in the Patients With Benign Prostatic Hyperplasia Who Undergo Holmium Laser Enucleation of the Prostate

NCT03460873

Benign Prostatic Hyperplasia (BPH)

COMPLETED

Photoselective Vaporization of the Prostate With the GreenLight XPS™ Laser System vs TURP for the Treatment of BPH

NCT01218672

Benign Prostatic Hyperplasia

COMPLETED NA

MRI Guided Transrectal Prostate Laser Ablation for Benign Prostatic Hypertrophy (BPH)

NCT03131544

BPH Prostate Hyperplasia Urinary Frequency/Urgency

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Lower Urinary Tract Symptoms Benign Prostatic Hyperplasia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

1

PVP group

Group Type ACTIVE_COMPARATOR

photoselective vaporization prostatectomy (PVP)

Intervention Type PROCEDURE

PVP using 80 W KTP laser with a Greenlight system (GreenLight PVTM, Laserscope®, San Jose, CA)

2

TURP group

Group Type ACTIVE_COMPARATOR

Transurethral resection of the prostate

Intervention Type PROCEDURE

Standard transurethral resection of the prostate using electrocautery loop

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

photoselective vaporization prostatectomy (PVP)

PVP using 80 W KTP laser with a Greenlight system (GreenLight PVTM, Laserscope®, San Jose, CA)

Intervention Type PROCEDURE

Transurethral resection of the prostate

Standard transurethral resection of the prostate using electrocautery loop

Intervention Type PROCEDURE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

PVP TURP

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Symptomatic BPH
* International Score Prostate Symptom (IPSS) of 13 or greater
* prostate volume of 30 to 100 ML
* Peak urinary flow rate (Qmax) less than 15 mL/s with a voided volume of \>125 mL and a PVR \<350mL
* Able to give fully informed consent

Exclusion Criteria

* Subjects with histological diagnosis of prostate cancer
* Subjects with history of chronic urinary retention
* Subjects with urethral stricture,
* Subjects with bladder neck contracture
* Subjects with urinary tract infection
* Subjects with prostate volume on TRUS of \>100 mL
* Subjects with suspected neurogenic bladder dysfunction
* Subjects who, in the opinion of investigator, are not likely to complete the study for whatever reason

Minimum Eligible Age

50 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No