Point-of-Care Computed Tomography (CT) Chronic Rhinosinusitis Study
NCT ID: NCT00871286
Last Updated: 2012-01-18
Study Results
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View full resultsBasic Information
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COMPLETED
NA
40 participants
INTERVENTIONAL
2009-03-31
2010-08-31
Brief Summary
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The investigators hypothesize that current guidelines, when applied to subjects with symptoms of CRS in the absence of physical signs may be associated with (1) increased unnecessary prescription of antibiotics, (2) delay in further essential workup, and (3) increased overall health care costs.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
DIAGNOSTIC
NONE
Study Groups
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CT scan (sinus) pre-tx
Sinus CT scan performed at initial otolaryngology (ear, nose, and throat)visit
Pre-treatment Sinus CT Scan
Pre-treatment Sinus CT Scan
CT scan (sinus) post-tx
Sinus CT scan performed after 3-4 weeks of antibiotic treatment and any other indicated medical treatment(s), per insurance company guidelines
Post-treatment Sinus CT Scan
Post-treatment Sinus CT Scan
Interventions
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Pre-treatment Sinus CT Scan
Pre-treatment Sinus CT Scan
Post-treatment Sinus CT Scan
Post-treatment Sinus CT Scan
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Subjects with a diagnosis of immune suppression or suspicion of malignancy that may be affecting the nose/paranasal sinuses
* Subjects who have had prior sinus surgery or who have been previously treated with a \>3 week course of broad spectrum antibiotics for CRS
18 Years
70 Years
ALL
No
Sponsors
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Northwestern University
OTHER
Responsible Party
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Rakesh Chandra
Associate Professor
Principal Investigators
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Rakesh K Chandra, MD
Role: PRINCIPAL_INVESTIGATOR
Northwestern University, Northwestern Medical Faculty Foundation, Northwestern Memorial Hospital
Locations
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Northwestern University/Northwestern Medical Faculty Foundation
Chicago, Illinois, United States
Countries
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References
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Stankiewicz JA, Chow JM. A diagnostic dilemma for chronic rhinosinusitis: definition accuracy and validity. Am J Rhinol. 2002 Jul-Aug;16(4):199-202.
Stankiewicz JA, Chow JM. Cost analysis in the diagnosis of chronic rhinosinusitis. Am J Rhinol. 2003 May-Jun;17(3):139-42.
Meltzer EO, Hamilos DL, Hadley JA, Lanza DC, Marple BF, Nicklas RA, Bachert C, Baraniuk J, Baroody FM, Benninger MS, Brook I, Chowdhury BA, Druce HM, Durham S, Ferguson B, Gwaltney JM Jr, Kaliner M, Kennedy DW, Lund V, Naclerio R, Pawankar R, Piccirillo JF, Rohane P, Simon R, Slavin RG, Togias A, Wald ER, Zinreich SJ; American Academy of Allergy, Asthma and Immunology; American Academy of Otolaryngic Allergy; American Academy of Otolaryngology-Head and Neck Surgery; American College of Allergy, Asthma and Immunology; American Rhinologic Society. Rhinosinusitis: Establishing definitions for clinical research and patient care. Otolaryngol Head Neck Surg. 2004 Dec;131(6 Suppl):S1-62. doi: 10.1016/j.otohns.2004.09.067.
Other Identifiers
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STU 8997
Identifier Type: -
Identifier Source: secondary_id
STU 8997
Identifier Type: -
Identifier Source: org_study_id
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