Infant Formula Supplemented With Probiotic Microorganisms and/or Prebiotic.

NCT ID: NCT00836771

Last Updated: 2013-07-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

270 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-07-31

Study Completion Date

2014-12-31

Brief Summary

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Evaluation the nutritional suitability of a based milk infant formula supplemented with friendly bacteria (probiotic microorganisms) and or nutritional fibers (prebiotic) to healthy, full term infants compare with an otherwise identical widely used commercially available milk based infant formula and/or breast feed

Detailed Description

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Conditions

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Focus on Healthy Infant Growth.

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Materna infant formula 1

milk based infant formula powder

Group Type PLACEBO_COMPARATOR

Infant Formula

Intervention Type DIETARY_SUPPLEMENT

Materna infant formula 2

Probiotic supplemented infant formula

Group Type EXPERIMENTAL

Infant Formula

Intervention Type DIETARY_SUPPLEMENT

Materna infant formula 3

Prebiotic supplemented infant formula

Group Type EXPERIMENTAL

Infant Formula

Intervention Type DIETARY_SUPPLEMENT

Materna infant formula 4

Prebiotic+ Probiotic supplemented infant formula

Group Type EXPERIMENTAL

Infant Formula

Intervention Type DIETARY_SUPPLEMENT

Human milk

Human Milk

Group Type OTHER

Infant Formula

Intervention Type DIETARY_SUPPLEMENT

Interventions

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Infant Formula

Intervention Type DIETARY_SUPPLEMENT

Other Intervention Names

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Materna

Eligibility Criteria

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Inclusion Criteria

* Healthy term infants of both sexes, born in natural labor .
* Single birth.
* Full term infants (born between the 37th and 42nd week of gestation)
* Infants with birth weight \>2500 g.
* Recruitment age will be 0-21 days.
* Infants whose mothers are unable to breast feed or have chosen not to breast feed prior to the study enrollment.
* Infants whose parents have agreed to participate in the study up to the age of 9 months..
* Infants whose parents have agreed to remain exclusively on the same product for 16 weeks of age..
* Infants whose parents have signed the informed consent form.
* Infants whose parents are able to understand the protocol requirements and to fill out the infant's diary and agree to completely fill out the parents' questionnaires during the period Of 9 months

Exclusion Criteria

* Twins.
* Premature or low birth weight (\< 2500 g).
* Chromosomal abnormalities or congenital malformation.
* Suffering jaundice which require phototherapy.
* Proven or suspected family history of allergy to cow's milk.
* Having been treated with antibiotics or other drugs during the last three days or more prior to the commencement of the study.
Minimum Eligible Age

1 Day

Maximum Eligible Age

21 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Materna Laboratories

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Nehama Linder, M.D. Ph.D

Role: PRINCIPAL_INVESTIGATOR

Neonatology department, Rabin Medical center, Petach Tikva. Israel

Raanan Shamir, M.D. Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Institute of Gastroenterology Nutrition and Liver Diseases Schneider children medical center, Petach Tikva.

Kobi Shiff, M.D.

Role: PRINCIPAL_INVESTIGATOR

Neonatology department, Laniado Hospital- Sanz Medical Center, Netanya, Israel.

Zvi Weizman, M.D. Ph.D

Role: PRINCIPAL_INVESTIGATOR

Department of Pediatrics, Soroka University Medical Center, Beer-Sheva, Israel.

Uri Rubenstein, M.D

Role: PRINCIPAL_INVESTIGATOR

clinic, 1 Yehuda Perach St., Natanya

Locations

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Neonatology department, Laniado Hospital- Sanz Medical Center, .

Netanya, , Israel

Site Status

Countries

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Israel

Other Identifiers

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80801

Identifier Type: -

Identifier Source: org_study_id

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