The Body's Response to Food Intake in Trained, Older Adults

NCT ID: NCT00798668

Last Updated: 2013-09-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-09-30

Study Completion Date

2008-05-31

Brief Summary

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The purpose of this research study is to determine the effects of food supplements and strength training on appetite, the amount of energy expended, and body composition.

Detailed Description

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Conditions

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Elderly

Keywords

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Endocrine and Gastrointestinal Response to Food

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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1

participants continue current exercise and take liquid supplement

Group Type EXPERIMENTAL

Liquid Supplements

Intervention Type DIETARY_SUPPLEMENT

Liquid supplement that provides 12.5% of the subjects total energy requirement.

2

Participants continue current exercise and take solid supplement

Group Type EXPERIMENTAL

Solid Supplement

Intervention Type DIETARY_SUPPLEMENT

Solid supplement that provides 12.5% of the subjects total energy requirement.

3

Participants continue current sedentary behavior and take liquid supplements

Group Type EXPERIMENTAL

Liquid Supplements

Intervention Type DIETARY_SUPPLEMENT

Liquid supplement that provides 12.5% of the subjects total energy requirement.

4

Participants continue current sedentary behavior and take solid supplements

Group Type EXPERIMENTAL

Solid Supplement

Intervention Type DIETARY_SUPPLEMENT

Solid supplement that provides 12.5% of the subjects total energy requirement.

Interventions

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Liquid Supplements

Liquid supplement that provides 12.5% of the subjects total energy requirement.

Intervention Type DIETARY_SUPPLEMENT

Solid Supplement

Solid supplement that provides 12.5% of the subjects total energy requirement.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

All subjects must meet the following eligibility criteria:

* Age range: 60 years and older
* Body mass index between 20-29 kg/m2
* Weight stable (\< 2 kg weight change within last 6 months)
* Non-smoking
* Constant habitual activity patterns within last 3 months
* Clinically normal blood profiles (specifically, normal liver and kidney function; normal complete blood count (non-anemic); fasting blood glucose \<110 mg/dl)
* Not taking medications known to influence appetite or metabolism
* Non-diabetic
* Confirmation of acceptability of eating the study test foods (solids and fluids)

Trained subjects (Recruiting 36; N-25) must meet the following eligibility criteria:

* Resistive exercise training (≥ 2 times a week) based on reported physical activity levels (questionnaire)
* Active fitness level (≥ 2, 30-minute aerobic exercise sessions/week)

Sedentary subjects (Recruiting 36; N-25) must meet the following eligibility criteria:

* Resistive exercise training (≤ 1 time a week) based on reported physical activity levels (questionnaire)
* Active fitness level (≤ 2, 30-minute aerobic exercise sessions/week)

Exclusion Criteria

All subjects will be excluded based on the following exclusionary criteria:

* Age: \<60 years
* Body mass index: outside of the 20-29 kg/m2 range
* Gained or lost \> 4.5 kg within the last 6 months
* Smoker (currently or within the last year)
* Intermittently been involved in a diet and/or exercise program within the last 3 months
* Clinically abnormal blood profiles as identified by our study physician, Arthur Rosen, MD
* Taking medications (currently or within the last 3 months) known to influence appetite or metabolism
* Abnormal heart function (interpreted by a cardiologist) and assessed (for study exclusion) by our study physician, Arthur Rosen, MD
* Clinically diagnosed as diabetic
* Study foods are found to be unacceptable for consumption by the subject
* Clinically diagnosed osteoporosis

Trained subjects will be excluded based on the following exclusionary criteria:

* Did not perform resistive exercise training (currently or within the last 3 months) based on reported physical activity levels (questionnaire)
* Perform ≤ 1, 30-minute aerobic exercise session/week (currently or within the last 3 months) based on physical activity levels questionnaire)

Sedentary subjects will be excluded based on the following exclusionary criteria:

* Performed resistive exercise training (currently or within the last 3 months) based on reported physical activity levels (questionnaire)
* Perform \> 2, 30-minute aerobic exercise sessions/week (currently or within the last 3 months) based on physical activity levels questionnaire)
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Purdue University

OTHER

Sponsor Role lead

Responsible Party

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Wayne Campbell

Professor, Foods and Nutrition

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Purdue University

West Lafayette, Indiana, United States

Site Status

Countries

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United States

Other Identifiers

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NIH R01 AG021911-0102

Identifier Type: -

Identifier Source: secondary_id

0607004184

Identifier Type: -

Identifier Source: org_study_id