Comparison of Medical Nutritional Supplements

NCT ID: NCT01483976

Last Updated: 2013-01-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

27 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-10-31

Study Completion Date

2012-05-31

Brief Summary

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The objective of this study is to verify changes in protein metabolism after ingesting a oral medical nutritional supplement.

Detailed Description

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Conditions

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Elderly

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Oral medical nutritional supplement without AN777

orally over a three hour period

Group Type ACTIVE_COMPARATOR

Oral medical nutritional supplement

Intervention Type OTHER

orally over a three hour period

Experimental oral medical nutritional supplement with AN777

orally over a three hour period

Group Type EXPERIMENTAL

Experimental oral medical nutritional supplement with AN777

Intervention Type OTHER

orally over a three hour period

Interventions

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Oral medical nutritional supplement

orally over a three hour period

Intervention Type OTHER

Experimental oral medical nutritional supplement with AN777

orally over a three hour period

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Male and is ≥ 60 and ≤ 90 years of age.
* Body Mass Index (BMI) \> 20.0, but \< 35.0.
* Ability to climb a flight of 10 stairs or walk an equivalent of city block without help within the 3 months prior to enrollment.
* Refrain from taking any dose of NSAIDs or acetaminophen on the day of and 24 hours prior to Visit 2 and Visit 3.
* Refrain from using any pulmonary maintenance medications on the days of Visit 2 and Visit
* Refrain from intense physical activity between visits.

Exclusion Criteria

* Systemic corticosteroids within the 3 months prior to enrollment.
* Blood thinner or anticoagulant medication within 1 week prior to enrollment.
* Glomerular filtration rate (eGFR) of \< 40 mL/min/1.73m2.
* Antibiotics within 1 week prior to enrollment.
* Major surgery less than 3 months prior to enrollment in the study.
* Active malignant disease or treated within the last 6 months for cancer.
* Immunodeficiency disorder.
* Diabetes
* Myocardial infarction 3 months prior to enrollment.
* Chronic obstructive pulmonary disease
* History of allergy to any of the ingredients in the study products.
* Conditions precluding ingestion or absorption of the study product, inflammatory bowel disease, short bowel syndrome, or other major gastrointestinal disease.
* Dementia, brain metastases, eating disorders, history of significant neurological or psychiatric disorder, or any other psychological condition.
* Pursuing weight loss or weight gain.
* Medications/dietary supplements/substances that could modulate metabolism or weight.
Minimum Eligible Age

60 Years

Maximum Eligible Age

90 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Abbott Nutrition

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Vikkie Mustad, PhD

Role: STUDY_CHAIR

Abbott Nutrition

Locations

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University of Arkansas for Medical Sciences

Little Rock, Arkansas, United States

Site Status

Countries

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United States

Other Identifiers

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BK96

Identifier Type: -

Identifier Source: org_study_id