Diet Composition - Metabolic Regulation and Long-term Compliance
NCT ID: NCT00692536
Last Updated: 2015-09-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
70 participants
INTERVENTIONAL
2007-09-30
2010-06-30
Brief Summary
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The following variables will be studied:
* Anthropometry
* DEXA
* OGTT
* Liver fat content measured with 1H-MRS
* Hepatic 11β-HSD1 activity, measured with cortisone/cortisol conversion test
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
NONE
Study Groups
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1
NNR
NNR (Nordic Nutrition Recommendations)
Diet with equal amounts of fat, protein and carbohydrates
2
MPD
MPD (Modified paleolithic diet)
A diet high in protein and fat, but low in carbohydrates
Interventions
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NNR (Nordic Nutrition Recommendations)
Diet with equal amounts of fat, protein and carbohydrates
MPD (Modified paleolithic diet)
A diet high in protein and fat, but low in carbohydrates
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Postmenopausal
* BMI\>28
Exclusion Criteria
* Gravidity
* Smoking
* Prescribed medication
70 Years
FEMALE
Yes
Sponsors
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Umeå University
OTHER
Responsible Party
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Mats Ryberg
MD, PhD
Principal Investigators
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Mats Ryberg, PhD, MD
Role: PRINCIPAL_INVESTIGATOR
Umeå University, Umeå, Sweden
Locations
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Umeå University
Umeå, , Sweden
Countries
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References
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Franklin KA, Lindberg E, Svensson J, Larsson C, Lindahl B, Mellberg C, Sahlin C, Olsson T, Ryberg M. Effects of a palaeolithic diet on obstructive sleep apnoea occurring in females who are overweight after menopause-a randomised controlled trial. Int J Obes (Lond). 2022 Oct;46(10):1833-1839. doi: 10.1038/s41366-022-01182-4. Epub 2022 Jul 25.
Hooper L, Martin N, Jimoh OF, Kirk C, Foster E, Abdelhamid AS. Reduction in saturated fat intake for cardiovascular disease. Cochrane Database Syst Rev. 2020 Aug 21;8(8):CD011737. doi: 10.1002/14651858.CD011737.pub3.
Hooper L, Martin N, Jimoh OF, Kirk C, Foster E, Abdelhamid AS. Reduction in saturated fat intake for cardiovascular disease. Cochrane Database Syst Rev. 2020 May 19;5(5):CD011737. doi: 10.1002/14651858.CD011737.pub2.
Manousou S, Stal M, Larsson C, Mellberg C, Lindahl B, Eggertsen R, Hulthen L, Olsson T, Ryberg M, Sandberg S, Nystrom HF. A Paleolithic-type diet results in iodine deficiency: a 2-year randomized trial in postmenopausal obese women. Eur J Clin Nutr. 2018 Jan;72(1):124-129. doi: 10.1038/ejcn.2017.134. Epub 2017 Sep 13.
Blomquist C, Alvehus M, Buren J, Ryberg M, Larsson C, Lindahl B, Mellberg C, Soderstrom I, Chorell E, Olsson T. Attenuated Low-Grade Inflammation Following Long-Term Dietary Intervention in Postmenopausal Women with Obesity. Obesity (Silver Spring). 2017 May;25(5):892-900. doi: 10.1002/oby.21815.
Boraxbekk CJ, Stomby A, Ryberg M, Lindahl B, Larsson C, Nyberg L, Olsson T. Diet-Induced Weight Loss Alters Functional Brain Responses during an Episodic Memory Task. Obes Facts. 2015;8(4):261-72. doi: 10.1159/000437157. Epub 2015 Jul 1.
Hammarstrom A, Wiklund AF, Lindahl B, Larsson C, Ahlgren C. Experiences of barriers and facilitators to weight-loss in a diet intervention - a qualitative study of women in northern Sweden. BMC Womens Health. 2014 Apr 16;14:59. doi: 10.1186/1472-6874-14-59.
Other Identifiers
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Um dnr 07-034M
Identifier Type: -
Identifier Source: org_study_id
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