Assessment of Efficacy of Vardenafil in the Treatment of Subjects With Symptomatic Benign Prostatic Hyperplasia

NCT ID: NCT00657839

Last Updated: 2014-10-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

222 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-10-31

Study Completion Date

2006-06-30

Brief Summary

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Assessment of efficacy of vardenafil in the treatment of subjects with symptomatic Benign Prostatic Hyperplasia.The purpose of this study is to find out whether vardenafil can improve the lower urinary tract symptoms of benign prostatic hyperplasia after 8 weeks of daily administration of 10 mg BID.

Detailed Description

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Conditions

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Benign Prostatic Hyperplasia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Arm 1

Group Type EXPERIMENTAL

Levitra (Vardenafil, BAY38-9456)

Intervention Type DRUG

10 mg Vardenafil bid

Arm 2

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

Matching placebo

Interventions

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Levitra (Vardenafil, BAY38-9456)

10 mg Vardenafil bid

Intervention Type DRUG

Placebo

Matching placebo

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Males 45 to 64 years of age
* Lower urinary tract symptoms \> 6 months
* International Prostate Symptom Score \> 12

Exclusion Criteria

* Prostate Specific Antigen \> 3 ng/ml
* Residual urine volume \> 150 m
* History of myocardial infarction, stroke or life-threatening arrhythmia within the prior 6 months
* Nitrate use
Minimum Eligible Age

45 Years

Maximum Eligible Age

64 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bayer Study Director

Role: STUDY_DIRECTOR

Bayer

Locations

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Biberach, Baden-Württemberg / 277, Germany

Site Status

München, Bayern / 280, Germany

Site Status

Rosenheim, Bayern / 280, Germany

Site Status

Starnberg, Bayern / 280, Germany

Site Status

Weiden, Bayern / 280, Germany

Site Status

Hamburg, Hamburg / 287, Germany

Site Status

Hamburg, Hamburg / 287, Germany

Site Status

Marburg, Hessen / 307, Germany

Site Status

Tostedt, Niedersachsen / 292, Germany

Site Status

Osnabrück, Niedersachsen / 293, Germany

Site Status

Düsseldorf, Nordrhein-Westfalen / 296, Germany

Site Status

Leverkusen, Nordrhein-Westfalen / 331, Germany

Site Status

Mülheim, Nordrhein-Westfalen / 481, Germany

Site Status

Leipzig, Sachsen / 313, Germany

Site Status

Kiel, Schleswig-Holstein / 306, Germany

Site Status

Countries

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Germany

Related Links

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http://www.clinicaltrialsregister.eu/

Click here to find information about studies related to Bayer Healthcare products conducted in Europe

Other Identifiers

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EudraCT No. 2005-002796-32

Identifier Type: -

Identifier Source: secondary_id

11863

Identifier Type: -

Identifier Source: org_study_id

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