A Study to Investigate the Time to Onset of Action of 10 mg and 20 mg of Vardenafil Compared to Placebo in Males With Erectile Dysfunction

NCT ID: NCT00665496

Last Updated: 2014-12-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

732 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-06-30

Study Completion Date

2003-11-30

Brief Summary

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This purpose of the study was to evaluate the earliest time to onset of action in adults with erectile dysfunction (often called impotence). In this study vardenafil has been compared to placebo. Patients were asked to fill in questionnaires and a diary in which they filled in details about attempts at sexual activity during study period. Patients received also a stopwatch to record the time of onset of erection. Stopwatch should be started immediately prior to initiating sexual activity and stopped when an erection perceived to be adequate for penetration was obtained.

Detailed Description

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Conditions

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Erectile Dysfunction

Keywords

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Erectile Dysfunction Vardenafil Onset of action

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Arm 1

Group Type EXPERIMENTAL

Levitra (Vardenafil, BAY38-9456)

Intervention Type DRUG

Vardenafil 10 mg and 20 mg orally once a day as needed

Arm 2

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

Matching Placebo

Interventions

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Levitra (Vardenafil, BAY38-9456)

Vardenafil 10 mg and 20 mg orally once a day as needed

Intervention Type DRUG

Placebo

Matching Placebo

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Males with ED for more than 6 months according to the NIH Consensus statement(inability to attain and/or maintain penile erection sufficient for satisfactory sexual performance)
* Heterosexual relationship
* 18 years and older

Exclusion Criteria

* Primary hypoactive sexual desire
* History of myocardial infarction, stroke or life threatening arrhythmia within the prior 6 months
* Nitrates or nitric oxide donors use
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bayer Study Director

Role: STUDY_DIRECTOR

Bayer

Locations

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Phoenix, Arizona, United States

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Beverly Hills, California, United States

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San Bernardino, California, United States

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Aurora, Colorado, United States

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Trumbull, Connecticut, United States

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Aventura, Florida, United States

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Jacksonville, Florida, United States

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Pembroke Pines, Florida, United States

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Lawrenceville, New Jersey, United States

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New York, New York, United States

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Charlotte, North Carolina, United States

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Wilmington, North Carolina, United States

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Calgary, Alberta, Canada

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Winnipeg, Manitoba, Canada

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Saint John, New Brunswick, Canada

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Kentville, Nova Scotia, Canada

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Barrie, Ontario, Canada

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Toronto, Ontario, Canada

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Montreal, Quebec, Canada

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Sherbrooke, Quebec, Canada

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Carpentras, , France

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Lille, , France

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Lyon, , France

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Lyon, , France

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Marseille, , France

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Montpellier, , France

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Nîmes, , France

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Paris, , France

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Garmisch-Partenkirchen, Bavaria, Germany

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München, Bavaria, Germany

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München, Bavaria, Germany

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Hamburg, City state of Hamburg, Germany

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Marburg, Hesse, Germany

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Hanover, Lower Saxony, Germany

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Osnabrück, Lower Saxony, Germany

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Westerstede, Lower Saxony, Germany

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Düsseldorf, North Rhine-Westphalia, Germany

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Mönchengladbach, North Rhine-Westphalia, Germany

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Niederkassel, North Rhine-Westphalia, Germany

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Leipzig, Saxony, Germany

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Halle, Saxony-Anhalt, Germany

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Milan, , Italy

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Milan, , Italy

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Modena, , Italy

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Napoli, , Italy

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Padua, , Italy

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Amsterdam, , Netherlands

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Nijmegen, , Netherlands

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Roermond, , Netherlands

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The Hague, , Netherlands

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Utrecht, , Netherlands

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Moelv, , Norway

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Oslo, , Norway

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Sarpsborg, , Norway

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Trondheim, , Norway

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Warsaw, Poland, Poland

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Kościerzyna, , Poland

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Lodz, , Poland

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Poznan, , Poland

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Warsaw, , Poland

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Wroclaw, , Poland

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Badalona, Barcelona, Spain

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Barcelona, Barcelona, Spain

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L'Hospitalet de Llobregat, Barcelona, Spain

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Galdakao, Bizkaia, Spain

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Castellon, Castellón de La Plana, Spain

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Barcelona, Catalonia, Spain

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Madrid, Madrid, Spain

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Zaragoza, Zaragoza, Spain

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Borås, , Sweden

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Gothenburg, , Sweden

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Skövde, , Sweden

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Stockholm, , Sweden

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Bristol, Avon, United Kingdom

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Bristol, Avon, United Kingdom

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Countries

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United States Canada France Germany Italy Netherlands Norway Poland Spain Sweden United Kingdom

Other Identifiers

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ONTIME

Identifier Type: -

Identifier Source: secondary_id

100492

Identifier Type: -

Identifier Source: org_study_id