Sustainable Efficacy of Vardenafil OD Versus Vardenafil PRN in Erectile Dysfunction

NCT ID: NCT00786253

Last Updated: 2014-10-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

236 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-10-31

Study Completion Date

2007-01-31

Brief Summary

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Compare once daily vs on demand treatment in men with erectile dysfunction.

Treatment of mild to moderate erectile dysfunction with 10 mg vardenafil p.o. over 24 weeks + 4 weeks wash-out:

A: once daily at bedtime for 12 weeks followed by 12 weeks of placebo B: once daily at bedtime for 24 weeksC: PRN for 24 weeks

Detailed Description

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Conditions

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Erectile Dysfunction

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Arm 1

Group Type EXPERIMENTAL

Levitra (Vardenafil, BAY38-9456)

Intervention Type DRUG

Vardenafil 10 mg on demand use

Arm 2

Group Type EXPERIMENTAL

Levitra (Vardenafil, BAY38-9456)

Intervention Type DRUG

Vardenafil daily dosing 10 mg

Interventions

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Levitra (Vardenafil, BAY38-9456)

Vardenafil 10 mg on demand use

Intervention Type DRUG

Levitra (Vardenafil, BAY38-9456)

Vardenafil daily dosing 10 mg

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Males 18-64 years of age
* Mild or mild to moderate ED (defined as \>15 and \<21 score points according to the Erectile Function Domain Score from IIEF as assessed at the randomisation visit)
* History of at least one of the following conditions: Diabetes mellitus type 2, hypertension, peripheral arterial occlusive disease
* Stable, heterosexual relationship for more than six months

Exclusion Criteria

* Primary hypoactive sexual desire
* History of myocardial infarction, stroke or life-threatening arrhythmia within prior 6 month
* Nitrate therapy.
Minimum Eligible Age

18 Years

Maximum Eligible Age

64 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bayer Study Director

Role: STUDY_DIRECTOR

Bayer

Locations

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Tübingen, Baden-Württemberg / 277, Germany

Site Status

München, Bayern / 280, Germany

Site Status

Regensburg, Bayern / 280, Germany

Site Status

Weiden, Bayern / 280, Germany

Site Status

Berlin, Berlin / 285, Germany

Site Status

Hamburg, Hamburg / 287, Germany

Site Status

Hamburg, Hamburg / 287, Germany

Site Status

Hamburg, Hamburg / 287, Germany

Site Status

Marburg, Hessen / 307, Germany

Site Status

Hagenow, Mecklenburg-Vorpommern / 309, Germany

Site Status

Hanover, Niedersachsen / 291, Germany

Site Status

Osnabrück, Niedersachsen / 293, Germany

Site Status

Düsseldorf, Nordrhein-Westfalen / 296, Germany

Site Status

Münster, Nordrhein-Westfalen / 298, Germany

Site Status

Leverkusen, Nordrhein-Westfalen / 331, Germany

Site Status

Grevenbroich, Nordrhein-Westfalen / 623, Germany

Site Status

Leipzig, Sachsen / 313, Germany

Site Status

Meißen, Sachsen / 313, Germany

Site Status

Halle, Sachsen-Anhalt / 311, Germany

Site Status

Countries

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Germany

Related Links

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http://www.clinicaltrialsregister.eu/

Click here to find information about studies related to Bayer Healthcare products conducted in Europe

Other Identifiers

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EudraCT No: 2005-001678-28

Identifier Type: -

Identifier Source: secondary_id

RESTORE

Identifier Type: -

Identifier Source: secondary_id

11875

Identifier Type: -

Identifier Source: org_study_id

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