To Investigate the Efficacy and Safety of Vardenafil in Men With Erectile Dysfunction.

NCT ID: NCT00661115

Last Updated: 2014-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

173 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-05-31

Study Completion Date

2004-02-29

Brief Summary

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To investigate the efficacy and safety of vardenafil in men with erectile dysfunction.

Detailed Description

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Conditions

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Erectile Dysfunction

Keywords

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Erectile dysfunction Sexual Dysfunction

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Arm 1

Group Type EXPERIMENTAL

Levitra (Vardenafil, BAY38-9456)

Intervention Type DRUG

Vardenafil 10 mg. After a 4 week run-in period, subjects were randomized in order to enroll 3 times more subjects in the vardenafil group than in the placebo group. The duration of the active treatment phase was 12 weeks

Arm 2

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

Placebo. After a 4 week run-in period, subjects were randomized in order to enroll 3 times more subjects in the vardenafil group than in the placebo group. The duration of the active treatment phase was 12 weeks

Interventions

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Levitra (Vardenafil, BAY38-9456)

Vardenafil 10 mg. After a 4 week run-in period, subjects were randomized in order to enroll 3 times more subjects in the vardenafil group than in the placebo group. The duration of the active treatment phase was 12 weeks

Intervention Type DRUG

Placebo

Placebo. After a 4 week run-in period, subjects were randomized in order to enroll 3 times more subjects in the vardenafil group than in the placebo group. The duration of the active treatment phase was 12 weeks

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Men 21 years or above with ED for more than 6 months with normal libido and stable heterosexual relationship of at least 6 months
* having at least a 50% failure rate of sexual intercourse attempts during the run-in phase

Exclusion Criteria

* Subjects with penile abnormalities, hypogonadism, history of unstable angina pectoris for 6 months or less, myocardial infarction, life threatening arrhythmia and history of unresponsiveness to sildenafil were excluded.
* Diabetic subjects with hemoglobin A1c (HbA1c) more than 12% were also excluded.
* Subjects could not be on androgens/anti-androgens or alpha blockers.
Minimum Eligible Age

21 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bayer Study Director

Role: STUDY_DIRECTOR

Bayer

Locations

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Bangalore, Karnataka, India

Site Status

Bangalore, Karnataka, India

Site Status

Belagum, Karnataka, India

Site Status

Mumbai, Maharashtra, India

Site Status

Mumbai, Maharashtra, India

Site Status

Madurai, Tamil Nadu, India

Site Status

Countries

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India

Other Identifiers

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10695

Identifier Type: -

Identifier Source: org_study_id