Examination of the Effects of Four Different Spices on Energy Metabolism

NCT ID: NCT00611156

Last Updated: 2008-02-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

22 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-10-31

Study Completion Date

2007-06-30

Brief Summary

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The objective of this study is to examine whether four different spices (ginger, black pepper, horseradish and mustard) are able to increase energy metabolism.

Since chili and other spices have been shown to increase energy expenditure compared to placebo, we expect that some or all of the four spices may actually increase energy expenditure - although not to a large degree.

Detailed Description

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Several pungent food ingredients, such as chili,and also other bioactive food ingredients, e.g. green tea, have been shown to be able to increase energy expenditure and fat oxidation during the hours following a meal containing the bioactive ingredient. Furthermore, we will also look at the subjects own feelings of appetite and thereby examine whether the appetite is affected by the spicy food. We expect to see some small effects on these parameters.

Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Investigators

Study Groups

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A

Spice

Group Type EXPERIMENTAL

ginger

Intervention Type DIETARY_SUPPLEMENT

added to a brunch meal

B

Spice

Group Type EXPERIMENTAL

black pepper

Intervention Type DIETARY_SUPPLEMENT

Added to a brunch meal

C

Spice

Group Type EXPERIMENTAL

horseradish

Intervention Type DIETARY_SUPPLEMENT

Added to a brunch meal

D

Spice

Group Type EXPERIMENTAL

mustard

Intervention Type DIETARY_SUPPLEMENT

Added to a brunch meal

E

Placebo

Group Type PLACEBO_COMPARATOR

placebo

Intervention Type DIETARY_SUPPLEMENT

Added to a bruch meal

Interventions

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ginger

added to a brunch meal

Intervention Type DIETARY_SUPPLEMENT

black pepper

Added to a brunch meal

Intervention Type DIETARY_SUPPLEMENT

horseradish

Added to a brunch meal

Intervention Type DIETARY_SUPPLEMENT

mustard

Added to a brunch meal

Intervention Type DIETARY_SUPPLEMENT

placebo

Added to a bruch meal

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* male
* healthy and not use medication (regularly)
* normal weight
* non smoker
* tolerate and like spicy food
* stable body weight last two months

Exclusion Criteria

* increased blood pressure
* abnormal EKG
* mental, metabolic and chronic diseases
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Aarhus

OTHER

Sponsor Role collaborator

University of Copenhagen

OTHER

Sponsor Role lead

Principal Investigators

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Arne Astrup, Professor MD

Role: STUDY_CHAIR

Department of Human Nutrition, RVAU

Locations

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Department of Human Nutrition, The Royal Veterinary and Agricultural University

Frederiksberg, , Denmark

Site Status

Countries

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Denmark

References

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Gregersen NT, Belza A, Jensen MG, Ritz C, Bitz C, Hels O, Frandsen E, Mela DJ, Astrup A. Acute effects of mustard, horseradish, black pepper and ginger on energy expenditure, appetite, ad libitum energy intake and energy balance in human subjects. Br J Nutr. 2013 Feb 14;109(3):556-63. doi: 10.1017/S0007114512001201. Epub 2012 Jul 5.

Reference Type DERIVED
PMID: 23021155 (View on PubMed)

Other Identifiers

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B228-IHE-2006-NTG

Identifier Type: -

Identifier Source: org_study_id

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