Effects of Mixed Nut Consumption on Satiety and Weight Management

NCT ID: NCT03375866

Last Updated: 2026-01-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

56 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-12-31

Study Completion Date

2028-12-31

Brief Summary

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The first goal of the proposed study is to determine acute and long-term effects of mixed nuts (almonds, hazelnuts, pecans, pistachios, walnuts, and peanuts) on metabolic parameters and weight management. While numerous studies have shown the beneficial effects of nuts on promoting negative energy balance and weight loss, mechanistic studies exploring how the inclusion of nuts in the diet promotes a negative energy balance and weight loss have not been conducted. The second goal is to determine the mechanisms by which mixed nut consumption regulates of food intake and body weight.

Detailed Description

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Conditions

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Satiety

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Pretzels

Group Type ACTIVE_COMPARATOR

Pretzels

Intervention Type OTHER

Subjects consume 240 kcal of pretzels daily for 16 weeks.

Mixed nuts

Group Type EXPERIMENTAL

Mixed nuts

Intervention Type OTHER

Subjects consume 240 kcal of mixed nuts daily for 16 weeks.

Interventions

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Pretzels

Subjects consume 240 kcal of pretzels daily for 16 weeks.

Intervention Type OTHER

Mixed nuts

Subjects consume 240 kcal of mixed nuts daily for 16 weeks.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 18-55 years old
* BMI 27-40

Exclusion Criteria

* Smoker
* Pregnant woman
* Required dietary supplement use
* Required medication of metabolic disorders
* Allergy to nuts or gluten
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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San Diego State University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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School of Exercise and Nutritional Sciences, SDSU

San Diego, California, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Mee Young Hong

Role: CONTACT

619-594-2392

Facility Contacts

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Mee Young Hong

Role: primary

619-594-2392

References

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Nora CL, Zhang L, Castro RJ, Marx A, Carman HB, Lum T, Tsimikas S, Hong MY. Effects of mixed nut consumption on LDL cholesterol, lipoprotein(a), and other cardiometabolic risk factors in overweight and obese adults. Nutr Metab Cardiovasc Dis. 2023 Aug;33(8):1529-1538. doi: 10.1016/j.numecd.2023.05.013. Epub 2023 May 15.

Reference Type DERIVED
PMID: 37263914 (View on PubMed)

Rosas M Jr, Liu C, Hong MY. Effects of Mixed Nut Consumption on Blood Glucose, Insulin, Satiety, and the Microbiome in a Healthy Population: A Pilot Study. J Med Food. 2023 May;26(5):342-351. doi: 10.1089/jmf.2022.0121. Epub 2023 Apr 20.

Reference Type DERIVED
PMID: 37083461 (View on PubMed)

Other Identifiers

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2515098

Identifier Type: -

Identifier Source: org_study_id

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