Clinical Trial of Novel Implantation Promoting Medium (EmbryoGlue) to Improve IVF Success Rates

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

150 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-05-31

Study Completion Date

2005-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Hypothesis: a special solution for improving human embryo implantation, when added to the solution during embryo transfer, will improve implantation rates in embryo transfers using previously frozen embryos.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

EmbryoGlue as an Embryo Transfer Medium

NCT03332680

Infertility

UNKNOWN NA

Comparative Study of Three Different Embryo Transfer Media in ICSI Cycles

NCT02792673

Improvement of Embryo Transfer Technique Improvement of Implantation

UNKNOWN NA

Hyaluronan-enriched Embryo Transfer Medium for Frozen-thawed Embryo Transfer

NCT02725827

In Vitro Fertilization Subfertility

COMPLETED NA

ISM1 Versus EmbrioGen Media for Embryo Culture With Previous Failure Implantation in ART Treatments

NCT01689454

Infertility Implantation Failure

UNKNOWN

Hyaluronan-enriched Medium and Euploid Blastocyst Transfers

NCT06165367

Infertility Implantation Rate Clinical Pregnancy Rate +3 more

RECRUITING NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

EmbryoGlue (TM) is added to embryo transfer solutions immediately prior to the transfer of frozen-thawed human embryos before placement of embryos into the patient uterus.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Embryo Implantation Infertility

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

A

Group Type EXPERIMENTAL

EmbryoGlue

Intervention Type OTHER

G2 culture media from Vitrolife which contains hyaluronic acid

B

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

EmbryoGlue

G2 culture media from Vitrolife which contains hyaluronic acid

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Frozen embryo transfer patients, men over the age of 18 and women between the ages of 18 and 42 completed years (if using their own eggs and with embryos frozen before 39 completed years) or 18 to 50 completed years if using donated eggs.

Exclusion Criteria

* Prior participation in this study, blastocyst transfers, single embryo transfer for medical reasons, prior embryo transfer with large amount of blood on the outside of the catheter, \> or = 3 consecutive failed embryo transfers at Mayo Clinic (fresh or frozen-thawed cycles).

Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes