Hyaluronan in Embryo Transfer Media

NCT ID: NCT02077608

Last Updated: 2014-03-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

580 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-31

Study Completion Date

2013-12-31

Brief Summary

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Prospective randomized double blind comparison of hyaluronan enriched embryotransfer media and conventional embryotransfer media in human IVF treatments. Embryos selected for transfer are incubated in a culture media containing high concentration of hyaluronan or low concentration of hyaluronan.

Primary outcome: implantation and pregnancy rates

Detailed Description

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Conditions

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Infertility

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Hyaluronan enriched transfer media

Embryos are incubated at least 10 minutes in hyaluronan enriched embryo transfer media before transfer

No interventions assigned to this group

Control group

Embryos are incubated in embryo transfer media containing low concentration of hyaluronan for at least 10 minutes before transfer

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Infertile patients
* entering in vitro fertilization treatment
* at least 1 embryo transferred

Exclusion Criteria

* IVF treatment with donated oocytes
* No embryo available for transfer
Minimum Eligible Age

18 Years

Maximum Eligible Age

48 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Peter Fancsovits, Ph.D.

OTHER

Sponsor Role lead

Responsible Party

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Peter Fancsovits, Ph.D.

Senior Clincial Embryologist

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Peter Fancsovits, Ph.D.

Role: STUDY_CHAIR

Semmelweis University First Department of Obstetrics and Gynecology

Janos Urbancsek, MD, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Semmelweis University First Department of Obstetrics and Gynecology

Adam Lehner, MSc

Role: PRINCIPAL_INVESTIGATOR

Semmelweis University First Department of Obstetrics and Gynecology

Locations

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Semmelweis University First Department of Obstetrics and Gynecology

Budapest, , Hungary

Site Status

Countries

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Hungary

References

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Bontekoe S, Heineman MJ, Johnson N, Blake D. Adherence compounds in embryo transfer media for assisted reproductive technologies. Cochrane Database Syst Rev. 2014 Feb 25;2014(2):CD007421. doi: 10.1002/14651858.CD007421.pub3.

Reference Type RESULT
PMID: 24567053 (View on PubMed)

Other Identifiers

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SemmelweisU-002

Identifier Type: -

Identifier Source: org_study_id

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