Training Cognitive Control Processes in Older Adults

NCT ID: NCT00586638

Last Updated: 2015-08-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-12-31

Study Completion Date

2010-02-28

Brief Summary

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Control processes are classes of brain activity that initiate, coordinate, synchronize, and regulate elemental cognitive functions for the conduct of goal-directed behavior. The proposed research investigates whether exposure to a computer-based training protocol designed to enhance cognitive control processes will improve cognitive performance in healthy older adults.

Detailed Description

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The proposed research investigates whether exposure to a computer-based training protocol designed to enhance cognitive control processes will improve cognitive performance in healthy older adults. Cognitively normal adults aged 60-75 will be randomized into three experimental groups: 1) Video game play with training strategy; 2) Video game play without training strategy (Active Control); 3) Minimal contact (Passive Control). Subjects in Groups 1 and 2 will be instructed to play the complex, high-demand video game, Space Fortress, for 36 one-hour sessions over 12 weeks. Subjects in Group 3 will receive all assessments but will not play the computer game.

Conditions

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Neurologic Manifestations Neurobehavioral Manifestations

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

SINGLE

Participants

Study Groups

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1

Video Game play with training strategy

Group Type EXPERIMENTAL

Video game based training

Intervention Type BEHAVIORAL

36 one-hour sessions over 12 weeks

2

Video game play without training strategy

Group Type ACTIVE_COMPARATOR

Video game based training

Intervention Type BEHAVIORAL

36 one-hour sessions over 12 weeks

3

Minimal contact control

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Video game based training

36 one-hour sessions over 12 weeks

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Age 60-75
* Willingness to adhere to training protocol
* Adequate English proficiency

Exclusion Criteria

* Known history of cognitive impairment, dementia, stroke, seizure disorder, or other neuropsychiatric condition judged to impact cognitive performance
* Taking medications known to influence cognitive performance
* Sensory (e.g. visual, auditory) or physical (e.g. severe arthritic, orthopedic, neurologic) impairment incompatible with use of a standard computer workstation.
* Enrolled in a concurrent study that could affect the outcome of this study
Minimum Eligible Age

60 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Columbia University

OTHER

Sponsor Role lead

Responsible Party

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Yaakov Stern

Professor of Clinical, Department of Neurology Administration

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Yaakov Stern, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Columbia University

Locations

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Columbia University Medical Center

New York, New York, United States

Site Status

Countries

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United States

References

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Blumen HM, Gopher D, Steinerman JR, Stern Y. Training cognitive control in older adults with the space fortress game: the role of training instructions and basic motor ability. Front Aging Neurosci. 2010 Nov 11;2:145. doi: 10.3389/fnagi.2010.00145. eCollection 2010.

Reference Type RESULT
PMID: 21120135 (View on PubMed)

Stern Y, Blumen HM, Rich LW, Richards A, Herzberg G, Gopher D. Space Fortress game training and executive control in older adults: a pilot intervention. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2011 Nov;18(6):653-77. doi: 10.1080/13825585.2011.613450. Epub 2011 Oct 12.

Reference Type RESULT
PMID: 21988726 (View on PubMed)

Other Identifiers

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AAAC6151

Identifier Type: -

Identifier Source: org_study_id

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