Posterior IVS Versus Sacrospinous Suspension in Vaginal Vault Prolapse Repair

NCT ID: NCT00153231

Last Updated: 2015-03-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

49 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-03-31

Study Completion Date

2007-05-31

Brief Summary

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Hypothesis / aims of study The aim of this multicentre study is to evaluate anatomical and functional results of an innovative posterior tape in vaginal prolapse repair by vaginal route, in comparison to the sacrospinous suspension.

Study design, materials and methods This study involves 5 centres in French Public Hospital. Patients will be randomly allocated to be operated by a sacrospinous suspension or by an posterior IVSTM (Tyco Healthcare, France). Prolapse severity will be evaluated using the POP-Q system. In order to evaluate the patient's quality of life, the validated PFDI and the PFIQ questionnaires will be used preoperatively and during follow-up, as well as a validated questionnaire on sexual problems. The difference on early post-operative pain should be 30% (40% for the sacrospinous suspension and 10% for the posterior IVS). Then the estimated number of patient is 40 in each arm.

Detailed Description

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Conditions

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Vaginal Prolapse

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

NONE

Study Groups

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Infracoccygeal sacropexy

Intervention: IVS

Group Type EXPERIMENTAL

IVS

Intervention Type DEVICE

Infracoccygeal sacropexy

Sacrospinofixation

Intervention: Sacrospinofixation

Group Type ACTIVE_COMPARATOR

Sacrospinofixation

Intervention Type PROCEDURE

Interventions

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IVS

Infracoccygeal sacropexy

Intervention Type DEVICE

Sacrospinofixation

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Age more than 18
* Vaginal vault prolapse of grade 2 or more (POP-Q system)
* Symptomatic prolapse

Exclusion Criteria

* Patient unable to read French language
* Cystocele without vaginal vault prolapse
* Vaginal vault prolapse of grade 1
* Associated rectal prolapse
* Rectal inflammatory disease (Crohn, RCH).
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Nīmes

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Renaud de Tayrac, MD

Role: PRINCIPAL_INVESTIGATOR

Hôpital Carémeau, Nimes, France

Locations

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Hôpital Carémeau

Nîmes, , France

Site Status

Countries

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France

Other Identifiers

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SPIC

Identifier Type: -

Identifier Source: org_study_id

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