Family-Based Prevention Program for Childhood Anxiety

NCT ID: NCT00078728

Last Updated: 2018-02-07

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-09-30

Study Completion Date

2007-07-31

Brief Summary

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This study will evaluate the effectiveness of a short-term family-based program for preventing anxiety disorders in at-risk children.

Detailed Description

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Anxiety disorders are serious conditions that can negatively impact a person's overall functioning. This study will enroll mothers with anxiety disorders and their children to determine whether a brief family-based intervention will reduce childhood anxiety better than standard care.

Participants will be randomly assigned to either the family-based prevention program or to evaluation only for 8 weeks. Participants in the prevention program will have weekly sessions with a therapist and will learn skills to help reduce anxiety. Self- and parent-reports, diagnostic interviews, a computerized memory task, and a videotaped parent-child interaction task will be used to assess participants. Assessments will be conducted at study start and one week after intervention completion (Week 9). Follow-up visits will be conducted at 6 and 12 months after intervention completion.

Conditions

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Anxiety Disorders

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Family-based anxiety prevention program

Participants will complete an 8 session (1 session/week), cognitive behavioral therapy-based, family prevention program to be administered by a trained clinician, after randomization to the study. The prevention program will include 3 booster sessions that take place after the first 8 sessions.

Group Type EXPERIMENTAL

Family-Based Anxiety Prevention Program

Intervention Type BEHAVIORAL

Participants in the prevention program will have weekly sessions with a therapist and will learn skills to help reduce anxiety for 8 weeks. The intervention will begin immediately after randomization to the study.

Evaluation only

Waitlist control group. Participants in this group will receive general information (in the form of a printed packet) about anxiety after randomization to the study. Families in this group will complete all study evaluations and will then be offered the option of participating in the prevention program. Families who accept will begin the prevention sessions and will receive the same CBT-based, family-based prevention program as the other treatment arm.

Group Type ACTIVE_COMPARATOR

Evaluation only

Intervention Type BEHAVIORAL

Participants will undergo evaluations without active treatment for 8 weeks.

Interventions

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Family-Based Anxiety Prevention Program

Participants in the prevention program will have weekly sessions with a therapist and will learn skills to help reduce anxiety for 8 weeks. The intervention will begin immediately after randomization to the study.

Intervention Type BEHAVIORAL

Evaluation only

Participants will undergo evaluations without active treatment for 8 weeks.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Mothers with a current, primary anxiety disorder
* 7-12 year old children without an anxiety disorder

Exclusion Criteria

* Mothers that do not have a current, primary anxiety disorder
* 7-12 year old children with an anxiety disorder
* 7-12 year old children that are currently receiving treatment for anxiety that could interfere with the study
Minimum Eligible Age

7 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute of Mental Health (NIMH)

NIH

Sponsor Role collaborator

Johns Hopkins University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Golda S. Ginsburg, PhD

Role: PRINCIPAL_INVESTIGATOR

Johns Hopkins University

Locations

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Johns Hopkins University School of Medicine

Baltimore, Maryland, United States

Site Status

Countries

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United States

Other Identifiers

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K23MH063427

Identifier Type: NIH

Identifier Source: secondary_id

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K23MH063427

Identifier Type: NIH

Identifier Source: org_study_id

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