A Study of Oral LY317615 in Relapsed or Refractory Diffuse Large B-Cell Lymphomas.

NCT ID: NCT00042666

Last Updated: 2020-08-10

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

55 participants

Study Classification

INTERVENTIONAL

Study Start Date

2002-06-30

Study Completion Date

2008-09-30

Brief Summary

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This study will measure the effectiveness and any side effects of LY317615 in participants with diffuse large B-cell lymphoma (DLBCL: a sub-type of Non-Hodgkins Lymphoma).

Detailed Description

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Conditions

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Non-Hodgkin's Lymphoma

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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LY317615

500 milligrams (mg), oral, daily (QD), up to six (6) 28-day cycles

Group Type EXPERIMENTAL

LY317615

Intervention Type DRUG

500 mg, oral, QD, up to six 28 day cycles

Interventions

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LY317615

500 mg, oral, QD, up to six 28 day cycles

Intervention Type DRUG

Other Intervention Names

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enzastaurin

Eligibility Criteria

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Inclusion Criteria

* A diagnosis of recurrent or refractory DLBCL.
* Adequate organ functions.
* Able to swallow capsules.

Exclusion Criteria

* More than 3 prior treatments for this disease.
* Serious heart problems.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Eli Lilly and Company

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern Time (UTC/GMT - 5 hours, EST)

Role: STUDY_DIRECTOR

Eli Lilly and Company

Locations

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For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon-Fri from 9AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Royal Oak, Michigan, United States

Site Status

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon-Fri from 9AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Minneapolis, Minnesota, United States

Site Status

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon-Fri from 9AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Rochester, Minnesota, United States

Site Status

Countries

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United States

Other Identifiers

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H6Q-MC-JCAI

Identifier Type: OTHER

Identifier Source: secondary_id

4849

Identifier Type: -

Identifier Source: org_study_id

NCT00054080

Identifier Type: -

Identifier Source: nct_alias

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