Clinical Trials
Showing trials with last updates posted in 2025.
244
Participants
Prevention and Treatment of Radiation-Induced Oral Mucositis in NPC With Houyanqing Oral Liquid
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2025-12-15
Completion:
2027-03-15
Conditions
Nasopharyngeal Cancinoma (NPC)
Radiation-induced Oral Mucositis
Interventions
DRUG
OTHER
No Results Yet
21
Participants
Safety and Efficacy of Intralesional 0.5% Triamcinolone Acetonide in 0.2% Fluconazole Solution vs 0.1% Topical Mometasone Furoate With 2% Miconazole Nitrate Cream in the Treatment of Chronic Paronychia: An Intraindividual Randomized Controlled Trial.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2024-08-17
Completion:
2025-12-04
Conditions
Chronic Paronychia
Interventions
DRUG
No Results Yet
36
Participants
Phase Ib/II Trial of Cladribine/Ruxolitinib/Venetoclax in Patients With Relapsed/Refractory T-cell Prolymphocytic Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2026-06-01
Completion:
2029-01-31
Conditions
T-cell Prolymphocytic Leukemia
Refractory T-Cell Prolymphocytic Leukemia
Interventions
DRUG
No Results Yet
28
Participants
Milky Way Sensor: Device Validation for Infiltrated Tissues
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2026-01-31
Completion:
2026-02-28
Conditions
Infiltration of Peripheral IV Therapy
Interventions
DEVICE
No Results Yet
[Trial of device that is not approved or cleared by the U.S. FDA]
Last Updated:
2025-12-31
No Results Yet
60
Participants
Primary Closure vs Open Technique for Pilonidal Sinus
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-07-01
Completion:
2023-12-31
Conditions
Pilonidal Sinus Disease
Sacrococcygeal Pilonidal Sinus
Chronic Infected Sinus Tract
Post-surgical Wound Healing
Interventions
PROCEDURE
No Results Yet
370
Participants
A Phase III Study Comparing HRS-4357 With Novel Androgen Receptor Pathway Inhibitors in Patients With Progressive, PSMA-Positive Metastatic Castration-Resistant Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2026-01-31
Completion:
2027-12-31
Conditions
PSMA-Positive Progressive Metastatic Castration-Resistant Prostate Cancer
Interventions
DRUG
No Results Yet
106
Participants
Stepwise Versus Conventional Training in Laparoscopic Suturing
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2020-10-14
Completion:
2023-06-30
Conditions
Learning Outcomes of Laparoscopic Suturing
Interventions
OTHER
No Results Yet
100
Participants
Validation of the Accuracy of an AI-Based System for Diagnosing Depressive Disorders
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2026-02-01
Completion:
2026-03-15
Conditions
Depressive Disorder
No Results Yet
100
Participants
Validation of the Accuracy of an AI-Based System for Diagnosing Anxiety Disorders
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2026-02-01
Completion:
2026-03-15
Conditions
Anxiety Disorders
No Results Yet
88
Participants
The Effect of Intraoperative Binaural Beats on Remimazolam Dose Required for Maintenance of General Anesthesia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2026-01-31
Completion:
2026-12-01
Conditions
Breast Reconstruction
Interventions
DEVICE
No Results Yet
450
Participants
Workplace Violence and Safety Perception Among ENT Physicians in Turkey
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2026-01-02
Completion:
2026-06-01
Conditions
Workplace Violence
Perceived Safety
Occupational Health
Otolaryngology-Head and Neck Surgery Physicians
Interventions
OTHER
No Results Yet
50
Participants
A Study on the Effectiveness of Preventive Extensive Release of the Rotator Interval and Joint Capsule to Reduce Postoperative Stiffness in Arthroscopic Rotator Cuff Repair
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2025-12-22
Completion:
2027-12-01
Conditions
Supraspinatus Tear
Interventions
PROCEDURE
No Results Yet
138
Participants
Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2026-01-02
Completion:
2028-09-20
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
4
Participants
A First-in-human Clinical Trial Evaluating a Novel Colonic Intraluminal Endoscopic Support Structure (CIESS)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2025-12-18
Completion:
2026-12-18
Conditions
Colon Polyp
Interventions
DEVICE
No Results Yet
43
Participants
Disitamab Vedotin Combined With Platinum and Bevacizumab as First-Line and Maintenance Therapy for HER2-Expressing, HRD-Negative High-Risk Ovarian Cancer: A Multicenter, Non-Randomized, Single-Arm Phase II Clinical Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2026-01-01
Completion:
2027-12-30
Conditions
Ovarian Cancer Metastatic
Ovarian Cancer Metastatic Recurrent
Interventions
DRUG
No Results Yet
112
Participants
A Comparison of Effectiveness, Safety, and Cost-effectiveness of Dapagliflozin and Empagliflozin in Patients With Type 2 Diabetes Mellitus and High Body Mass Index (BMI)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2025-12-24
Completion:
2026-12-31
Conditions
Type 2 Diabetes
Interventions
DRUG
No Results Yet
56
Participants
Phase IIa Study of BRY812 Monotherapy in Advanced Gynecological Malignancies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2025-12-31
Completion:
2027-12-31
Conditions
Advanced Gynecological Malignancies
Interventions
DRUG
No Results Yet
30
Participants
PMPR and Chlorhexidine on Periodontal Disease and Vascular Function
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2026-01-23
Completion:
2028-07-01
Conditions
Periodontal Disease (PD)
Cardio Vascular Disease
Oral-Systemic Link
Vascular Dysfunction
Endothelial Function and Arterial Stiffness
Interventions
OTHER
No Results Yet
60
Participants
Improvement of Sleep in COPD Patients Through Inhalation Management Education by Nurse.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2026-01-31
Completion:
2026-12-31
Conditions
Chronic Obstructive Lung Disease
Interventions
BEHAVIORAL
No Results Yet
1000
Participants
Implementation of Biomarker-Based Care for mTBI - IMPACTS-BRAINI Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2025-07-15
Completion:
2026-05-01
Conditions
Mild Traumatic Brain Injury (mTBI)
Interventions
DIAGNOSTIC_TEST
No Results Yet
150
Participants
Comprehensive Outcomes of Palatal TSADs Treatment
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-01-03
Completion:
2025-09-10
Conditions
Malocclusions
Interventions
DEVICE
No Results Yet
28
Participants
HIIT, Steroid Hormones and Mental Health in Adolescents
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2024-11-01
Completion:
2025-01-25
Conditions
Hormone
Interventions
BEHAVIORAL
No Results Yet
50
Participants
Target-Controlled Infusion and Postoperative Neurocognitive Outcomes in Geriatric Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2025-05-05
Completion:
2025-10-31
Conditions
Postoperative Cognitive Dysfunction (POCD)
Neurocognitive Function
Sedation and Analgesia
Geriatric Patients
No Results Yet
300
Participants
Sleep and Morning Wellbeing Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2026-01-01
Completion:
2026-06-01
Conditions
Sleep
Relaxation
Stress
Daytime Sleepiness
Interventions
DIETARY_SUPPLEMENT
No Results Yet
49
Participants
Raman Spectroscopy-Based Non-Invasive Blood Glucose Detection
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2026-01-01
Completion:
2026-06-10
Conditions
Diabetes
Interventions
DIAGNOSTIC_TEST
No Results Yet
40
Participants
SHR-1701 + Rivoceranib (± SHR-2554) in Advanced GC After First-Line Immunotherapy Failure
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2026-01-01
Completion:
2028-01-01
Conditions
Gastric Cancer (GC)
Gastroesophageal Junction Adenocarcinoma
Interventions
DRUG
No Results Yet
100
Participants
Local Subcutaneous Gentamicin for Prevention of Surgical Site Infection After Elective Cesarean Section
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2025-12-08
Completion:
2026-01-07
Conditions
Surgical Site Infection
Interventions
DRUG
No Results Yet
95
Participants
Examination of the Relationship Between Quality of Life and Caregiving Burden Among Caregivers of Pediatric Oncology Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2026-01-01
Completion:
2026-03-31
Conditions
Childhood Cancer
Childhood Cancers
Caregiver Subjective Burden
Primary Caregivers of Children Newly Diagnosed With Cancer
Caregiver
Caregiver Anxiety
Caregiver Health Related QOL
Interventions
BEHAVIORAL
No Results Yet
50
Participants
Impact of Immunotherapy on Vestibular Function, The Mayo Clinic Arizona Experience
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2025-10-31
Completion:
2027-10-31
Conditions
Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm
Interventions
OTHER
No Results Yet
1000
Participants
Increasing Germline Genetic Testing for Patients With Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2026-01-01
Completion:
2030-01-01
Conditions
Hereditary Pancreatic Cancer
Conditions or Focus of Study
Hereditary Breast Cancer
Hereditary Colorectal Cancer
Interventions
BEHAVIORAL
No Results Yet
226
Participants
Effect of Narrative Education on Glycemic Control in Adults With Type 2 Diabetes in Primary Care
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2026-02-15
Completion:
2026-11-15
Conditions
Type 2 Diabetes Mellitus (T2DM)
Diabetes Self-management
Diabetes Education
Interventions
BEHAVIORAL
No Results Yet
6
Participants
Exercise in Extreme Hot Weather Conditions
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2025-07-07
Completion:
2025-12-10
Conditions
Heat Acclimation and Thermotolerance
Heat Effect
Interventions
OTHER
No Results Yet
276
Participants
CT-Based Deep Learning for Differentiating Acute and Chronic Osteoporotic Vertebral Compression Fractures
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2025-12-16
Completion:
2025-12-29
Conditions
Osteoporotic Vertebral Compression Fractures
Interventions
OTHER
No Results Yet
30
Participants
Regenerative Treatment of Female Genital Atrophy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2024-06-04
Completion:
2025-06-18
Conditions
Vulvo Vaginal Atrophy
Interventions
BIOLOGICAL
OTHER
No Results Yet
84
Participants
Flipped Classroom Sexual Health Education Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2025-11-02
Completion:
2025-12-17
Conditions
Sexual Health
Health Literacy
Health Education
Flipped Classroom Model in Teaching
Randomized Controlled Trial
Interventions
BEHAVIORAL
No Results Yet
100
Participants
Pilot Study: Effects of CCP Intervention on NICU Environment and Preterm Infants Development
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2025-12-22
Completion:
2028-12-31
Conditions
Preterm Infant Development
Preterm Infant Health
Interventions
BEHAVIORAL
No Results Yet
118
Participants
Sequential Compression Device and Range of Motion Exercises on Distributive Peripheral Edema and Hemodynamic Stability Among Patients in Critical Care Units
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2025-12-28
Completion:
2026-03-15
Conditions
Peripheral Edema
Interventions
DEVICE
No Results Yet
10000
Participants
Cohort Study on Medical Students' Mental Health
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2025-10-22
Completion:
2047-10-31
Conditions
Major Depressive Disorder
Generalized Anxiety Disorder
Suicidal Ideation
Alcoholism
Marijuana Abuse
Loneliness
Interventions
OTHER
No Results Yet
150
Participants
The Combined Effect of Magnesium, Palmitoylethanolamide, High-Molecular-weight Hyaluronic Acid, Vitamin B6, and Vitamin D in Preventing Preterm Birth:
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2026-01-01
Completion:
2027-04-01
Conditions
Preterm Labor
Interventions
DRUG
OTHER
No Results Yet
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