MedDataX Logo

HIIT, Steroid Hormones and Mental Health in Adolescents

NCT ID: NCT07311460

Last Updated: 2025-12-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-11-01

Study Completion Date

2025-01-25

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of study was to investigate the effect of a high-intensity interval training (HIIT) intervention on cardiorespiratory fitness (CRF), hormonal, and mental health markers in male adolescents. The main question it aims to answer is: Does HIIT improve CRF, hormonal (testosterone and cortisol levels, testosterone:cortisol ratio), and mental health (depression, anxiety and stress scores) markers. Researchers will compare HIIT (designed to experimental group) to non-training intervention (designed to control group) to see if the training program works to improve the health status. HIIT consisted of three sessions per week for 10 weeks, comprising of three sets of four to eight bouts of 30-s runs at high intensity \[100-110% of maximal aerobic speed (MAS)\], interspersed with 30-s recovery runs at low intensity (50% of MAS) between bouts.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

High-intensity interval training (HIIT) is a time-efficient method for improving physical fitness in youth. However, limited evidence exists regarding its effects on testosterone and cortisol levels, testosterone:cortisol ratio, and mental health outcomes during adolescence, a critical period of development. This study was to investigate the effect of a HIIT intervention on cardiorespiratory fitness (CRF, expressed as maximal aerobic speed and maximal oxygen consumption), hormonal, and mental health markers in male adolescents. Twenty-eight healthy male adolescents (age, 14.9±0.74 yrs.) were randomized to a HIIT group (HIITG, n=15) or a non-training control group (CG, n=13). HIIT consisted of three sessions per week for 10 weeks, comprising of three sets of four to eight bouts of 30-s runs at high intensity \[100-110% of maximal aerobic speed (MAS)\], interspersed with 30-s recovery runs at low intensity (50% MAS) between bouts. Pre- and post-intervention assessments included CRF (VO2max), hormonal markers (testosterone, cortisol, and testosterone:cortisol ratio), and mental health markers (depression, anxiety and stress scores).

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Hormone

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

adolescences hormones training period mental health physical performance

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

High-intensity interval training (HIIT) group

The HIIT group performed a HIIT program consisting of three sessions per week for 10 weeks, including three sets of four to eight bouts of 30-second runs at high intensity (100-110% of maximal aerobic speed, MAS), interspersed with 30-second recovery runs at low intensity (50% MAS) between bouts.

Group Type EXPERIMENTAL

High-intensity interval training (HIIT) program

Intervention Type BEHAVIORAL

The HIIT program consisted of three sessions per week for 10 weeks, comprising of three sets of four to eight bouts of 30-s runs at high intensity \[100-110% of maximal aerobic speed (MAS)\], interspersed with 30-s recovery runs at low intensity (50% MAS) between bouts.

Control group

The participants in the control group maintained their normal daily activities.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

High-intensity interval training (HIIT) program

The HIIT program consisted of three sessions per week for 10 weeks, comprising of three sets of four to eight bouts of 30-s runs at high intensity \[100-110% of maximal aerobic speed (MAS)\], interspersed with 30-s recovery runs at low intensity (50% MAS) between bouts.

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* male sex,
* age 14 to 16 years,
* normal weight according to the WHO child growth standards for BMI (BMI ≤ 85th percentile)
* parental approval.

Exclusion Criteria

* medical conditions contraindicating intense physical exercise
* non-compliance with the training program
* habitual physical activity exceeding school physical education lessons
* current or recent (within 3 months) dietary supplementation or restriction
* incomplete data.
Minimum Eligible Age

14 Years

Maximum Eligible Age

16 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

High Institute of Sports and Physical Education of Kef

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Nejmeddine Ouerghi

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Nejmeddine Ouerghi, Ph.D

Role: PRINCIPAL_INVESTIGATOR

Research Unit "Sport Sciences, Health and Movement"(UR22JS01) High Institute of Sport and Physical Education of Kef, University of Jendouba, 7100 Kef, Tunisia.

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Tunisia

El Kef, Boulifa, Tunisia

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Tunisia

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

HIIT-ADO-Stroid-H

Identifier Type: -

Identifier Source: org_study_id