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Clinical Trials

Showing trials with last updates posted in 2025.

NCT07073079 | RECRUITING
250 Participants

A Study to Assess the Effectiveness of Second-Line Therapy of Upadacitinib and Risankizumab in Adult Participants With Crohn's Disease in a Real-World Setting

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2025-07-14
Completion: 2027-12-31
Conditions
Crohn's Disease
No Results Yet
NCT07072585 | NOT_YET_RECRUITING | PHASE2/PHASE3
1708 Participants

Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-06-28
Completion: 2035-09-01
Conditions
Stage II T Lymphoblastic Leukemia/Lymphoma Stage III T Lymphoblastic Leukemia/Lymphoma Stage IV T Lymphoblastic Leukemia/Lymphoma T Acute Lymphoblastic Leukemia T Lymphoblastic Lymphoma
Interventions
PROCEDURE DRUG BIOLOGICAL OTHER RADIATION
No Results Yet
NCT07069790 | RECRUITING | NA
24 Participants

Effects of Chemotherapy Treatment on Metaboreflex, Mechanoreflex, and Baroreflex Function: PROTECT-08B Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-10-02
Completion: 2026-10-02
Conditions
Breast Adenocarcinoma
Interventions
OTHER
No Results Yet
NCT07067658 | RECRUITING | NA
300 Participants

Monitoring Oedema in Heart Failure to Improve Function and Reduce Hospitalisation Risk

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-18
Completion: 2027-01-31
Conditions
Heart Failure
Interventions
DEVICE OTHER
No Results Yet
NCT07060885 | RECRUITING | PHASE3
300 Participants

A Research Study of House Dust Mite (HDM) SLIT-tablet for the Treatment of HDM Allergy in Chinese Participants Aged 12-65

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-09-01
Completion: 2026-07-31
Conditions
Allergic Rhinoconjunctivitis Allergic Rhinitis
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT07056764 | COMPLETED | NA
25 Participants

Development of Lung Vibration Equipment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-02-08
Completion: 2025-10-31
Conditions
Sputum Removal
Interventions
OTHER DEVICE
No Results Yet
NCT07052370 | RECRUITING | PHASE1
30 Participants

TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-09-25
Completion: 2028-12-31
Conditions
Hematologic Malignancy
Interventions
DRUG DEVICE
No Results Yet
NCT07049692 | NOT_YET_RECRUITING | NA
424 Participants

Hyperbaric Oxygen After Stroke Thrombectomy: A Multicenter Randomized Trial on Safety and Efficacy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-02-01
Completion: 2028-03-30
Conditions
Acute Ischemic Stroke
Interventions
OTHER
No Results Yet
NCT07049575 | RECRUITING | PHASE1
24 Participants

Study to Evaluate the Maximal Use of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-11-03
Completion: 2026-12-09
Conditions
Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
NCT07045792 | ACTIVE_NOT_RECRUITING | NA
62 Participants

Body Awareness Therapy in High Stressed Young Adults: Effects on Function, Balance, Sleep and Mood

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-05-30
Completion: 2025-11-30
Conditions
Stress Psychological Factors Sleep Postural Balance
Interventions
PROCEDURE
No Results Yet
NCT07044414 | COMPLETED | NA
34 Participants

Effectiveness of Manual Acupuncture for Head and Neck Cancer Patients Undergoing Chemoradiation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-09-01
Completion: 2025-12-12
Conditions
Head and Neck Neoplasms
Interventions
DEVICE
No Results Yet
NCT07042685 | RECRUITING | PHASE2
50 Participants

Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-31
Completion: 2028-12-31
Conditions
Metastatic Colorectal Cancer (CRC)
Interventions
DRUG
No Results Yet
NCT07039175 | RECRUITING | PHASE3
270 Participants

Intervention to Increase Intention to Change Alcohol/Tobacco Use in Veterans With Chronic Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-10-01
Completion: 2028-12-31
Conditions
Tobacco Smoking Alcohol-Related Disorders
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT07037199 | RECRUITING | PHASE2
45 Participants

Efficacy and Safety of Trastuzumab Rezetecan Followed by CDK4/6 Inhibitors and Endocrine Therapy in HR+/HER2-Low/Ultra-Low Advanced Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-08-18
Completion: 2028-06-30
Conditions
Advanced Breast Cancer
Interventions
DRUG
No Results Yet
NCT07036003 | RECRUITING | PHASE1/PHASE2
34 Participants

Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-10-31
Completion: 2028-07-31
Conditions
Knee Osteoarthritis (Knee OA) Knee Osteoarthritis (OA)
Interventions
DRUG
No Results Yet
NCT07030699 | RECRUITING | PHASE2
27 Participants

A Study of Epcoritamab With Lenalidomide and Tafasitamab in People With Diffuse Large B Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-08-13
Completion: 2028-08-31
Conditions
Lymphoma
Interventions
DRUG
No Results Yet
NCT07030452 | COMPLETED | NA
40 Participants

Laser Acupuncture for Pulmonary Function Test and Quality of Life in COPD Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-08-01
Completion: 2025-12-10
Conditions
Chronic Pulmonary Obstruction
Interventions
DEVICE
No Results Yet
NCT07029035 | COMPLETED | NA
20 Participants

Evaluation of Repeated Injectable PRF Following SRP in Patients With Periodontitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-12-01
Completion: 2024-12-01
Conditions
Periodontitis Stage III
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT07028268 | RECRUITING | PHASE2
210 Participants

A Trial of SHR-2017 Injection in Patients With Bone Metastases From Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-06-24
Completion: 2025-12-31
Conditions
For Prevention of Bone Events in Patients With Bone Metastases From Solid Tumors
Interventions
DRUG
No Results Yet
NCT07024797 | COMPLETED | PHASE1
20 Participants

Study to Assess the Adverse Events, Tolerability, and How Oral Doses of ABBV-932 Moves Through the Body in Healthy Adult Chinese Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-08-21
Completion: 2025-12-08
Conditions
Healthy Volunteer
Interventions
DRUG
No Results Yet
NCT07023627 | RECRUITING | PHASE2
160 Participants

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-11-12
Completion: 2027-04-27
Conditions
Ovarian Cancer
Interventions
DRUG
No Results Yet
NCT07021638 | RECRUITING | NA
30 Participants

EMMVIES : Walking Training at Home in VIrtual Reality for Children With Chronic Illnesses Impacting Physical Health

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-24
Completion: 2027-12-01
Conditions
Home-based Programs EzyGain AMY Treadmill Cerebral Palsy Neuromuscular Diseases (NMD) Obesity Virtual Reality
Interventions
OTHER
No Results Yet
NCT07018128 | RECRUITING | NA
200 Participants

Expression of Genes Relating Hypertension and Efficacy of 4-7-8 Breathing Control on Reducing Blood Pressure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-10-01
Completion: 2026-03-30
Conditions
Genetic Predisposition to Disease Breathing, Mouth
Interventions
OTHER
No Results Yet
NCT07008235 | RECRUITING | PHASE2/PHASE3
120 Participants

Effect of Amitriptyline and Trifluoperazine on Patients With Functional Dyspepsia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-07-01
Completion: 2026-06-30
Conditions
Functional Dyspepsia
Interventions
DRUG
No Results Yet
NCT06999603 | RECRUITING | PHASE2
550 Participants

Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-09-02
Completion: 2027-04-30
Conditions
Viral Pneumonia
Interventions
DRUG
No Results Yet
NCT06997094 | NOT_YET_RECRUITING | PHASE1
24 Participants

Decitabine in Combination With Standard of Care Therapy for the Treatment of Surgically Resectable HPV-Negative Head and Neck Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-30
Completion: 2027-11-08
Conditions
Human Papillomavirus-Negative Neck Squamous Cell Carcinoma Resectable Head and Neck Squamous Cell Carcinoma Resectable Human Papillomavirus-Independent Head and Neck Mucosal Squamous Cell Carcinoma HPV-Negative Squamous Cell Carcinoma Resectable Head and Neck Squamous-cell Carcinoma
Interventions
PROCEDURE DRUG RADIATION OTHER
No Results Yet
NCT06992947 | COMPLETED | NA
538 Participants

Impact of Healthy Food Subsidies on Diet Quality and Food Security

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-06-07
Completion: 2025-12-16
Conditions
Food Insecurity
Interventions
OTHER
No Results Yet
NCT06990711 | RECRUITING | PHASE1
30 Participants

A Phase 1 Clinical Trial of Siltuximab for the Treatment of Antibody-Mediated Rejection After Lung Transplantation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-11-06
Completion: 2027-12-30
Conditions
Antibody Mediated Rejection of Lung Transplant
Interventions
DRUG
No Results Yet
NCT06987305 | RECRUITING | PHASE3
820 Participants

Intravenous rhTNK-tPA Before Stroke Thrombectomy in the Extended Time Window

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-10-21
Completion: 2027-10-31
Conditions
Stroke, Acute Ischemic
Interventions
DRUG PROCEDURE
No Results Yet
NCT06982521 | RECRUITING | PHASE3
540 Participants

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-08-26
Completion: 2028-04-30
Conditions
PIK3CA Mutation HER2- Negative Breast Cancer Hormone Receptor Positive Tumor Breast Cancer Metastatic Breast Cancer Advanced Breast Cancer
Interventions
DRUG
No Results Yet
NCT06979375 | RECRUITING | PHASE2
200 Participants

A Research Study Comparing CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Reduced/Mildly Reduced Ejection Fraction and Left Ventricular Hypertrophy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-06-30
Completion: 2027-05-16
Conditions
Heart Failure
Interventions
DRUG
No Results Yet
NCT06978816 | NOT_YET_RECRUITING | NA
116 Participants

Ear Pressure Points Plus Pain Meds for Faster Kidney Stone Pain Relief

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-01
Completion: 2025-12-30
Conditions
Renal Colic Acupuncture, Ear
Interventions
DRUG OTHER
No Results Yet
NCT06978660 | RECRUITING
500 Participants

Multicenter Study for the Validation of an AI-based ECG Platform for Early Cardiac Amyloidosis Diagnosis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2025-05-27
Completion: 2026-03-31
Conditions
Transthyretin Cardiac Amyloidosis
No Results Yet
NCT06965569 | COMPLETED | PHASE1
37 Participants

Multiple Ascending Dose Phase 1 Study of ALA-3000

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-04-21
Completion: 2025-12-30
Conditions
Treatment Resistant Depression
Interventions
DRUG
No Results Yet
NCT06964542 | COMPLETED | NA
32 Participants

Effect of Supervised in Comparison to Non-supervised Multicomponent Exercise Training on Balance and Quality of Life in Peripheral Diabetic Neuropathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-09-10
Completion: 2025-05-15
Conditions
Peripheral Diabetic Neuropathy
Interventions
PROCEDURE
No Results Yet
NCT06963606 | RECRUITING | NA
22000 Participants

Effectiveness of Computer-Aided Detection Chest X-Ray Screening for Improving Tuberculosis Diagnostic Yield in Chinese Primary Health Care Settings: Study Protocol for a Prospective Cluster Randomized Controlled Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-09-01
Completion: 2027-12-31
Conditions
Tuberculosis (TB)
Interventions
DIAGNOSTIC_TEST OTHER
No Results Yet
NCT06959238 | COMPLETED | NA
30 Participants

Investigation of the Effects of Basic Body Awareness Therapy on Core Muscle Endurance, Posture, Balance, Quality of Life and Body Awareness in Earthquake Victims

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-05-01
Completion: 2025-05-20
Conditions
Earthquake Core Posture Balance Quality of Life Body Awareness
Interventions
OTHER
No Results Yet
NCT06958510 | COMPLETED | NA
24 Participants

Modified Anatomical Mesh In The Management Of Orbito-Zygomatico-Maxillary Complex Fractures

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-10-01
Completion: 2025-03-01
Conditions
Orbital Fractures Zygomatic Fractures
Interventions
DEVICE
No Results Yet
NCT06956118 | NOT_YET_RECRUITING | NA
60 Participants

Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Improving Sleep in Visually Impaired Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-11-30
Completion: 2026-06-30
Conditions
Sleep Quality Quality of Lifte Non-24 Sleep-Wake Disorder
Interventions
DEVICE
No Results Yet
NCT06947837 | COMPLETED
200 Participants

Study on the Influencing Mechanism and Promoting Strategies of Post-partum Nurses' Work Engagement

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2025-09-30
Completion: 2025-12-20
Conditions
Nurses Postpartum Work Engagement
No Results Yet
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