Clinical Trials

Showing trials with last updates posted in 2025.

NCT03420482 | ACTIVE_NOT_RECRUITING | PHASE2
30 Participants

Fecal Microbiota Transplant as Treatment of Hepatic Encephalopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2018-04-01
Completion: 2026-12-31
Conditions
Hepatic Encephalopathy
Interventions
DRUG
No Results Yet
NCT03405155 | COMPLETED | PHASE2
26 Participants

Nivolumab in Treating Patients With Stage IIB-IIC Melanoma That Can Be Removed by Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2018-01-17
Completion: 2025-12-15
Conditions
Melanoma (Skin)
Interventions
BIOLOGICAL
No Results Yet
NCT03404193 | ACTIVE_NOT_RECRUITING | PHASE2
235 Participants

Venetoclax and Decitabine in Treating Participants With Relapsed/Refractory Acute Myeloid Leukemia or Relapsed High-Risk Myelodysplastic Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2018-01-18
Completion: 2027-12-31
Conditions
Acute Myeloid Leukemia Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome Blastic Plasmacytoid Dendritic Cell Neoplasm Chronic Myelomonocytic Leukemia Mixed Phenotype Acute Leukemia Myelodysplastic Syndrome Recurrent Acute Biphenotypic Leukemia Recurrent Acute Myeloid Leukemia Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm Recurrent Chronic Myelomonocytic Leukemia Recurrent Mixed Phenotype Acute Leukemia Refractory Acute Myeloid Leukemia Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm Refractory Chronic Myelomonocytic Leukemia Refractory Mixed Phenotype Acute Leukemia
Interventions
DRUG OTHER
No Results Yet
NCT03397667 | COMPLETED | NA
236 Participants

The Aging Brain ANSWERS Program

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2018-08-01
Completion: 2023-05-31
Conditions
Traumatic Brain Injury Alzheimer Disease Veterans Family Caregivers Caregiver Burden Quality of Life
Interventions
OTHER
No Results Yet
NCT03388606 | RECRUITING
4100 Participants

Characterization and Treatment of Adolescent Depression

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2017-12-28
Completion: 2026-07-01
Conditions
Depression
Interventions
BEHAVIORAL
No Results Yet
NCT03274492 | ACTIVE_NOT_RECRUITING | PHASE3
1000 Participants
NCT03250247 | ACTIVE_NOT_RECRUITING | NA
225 Participants

Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The C-TRACT Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2018-07-02
Completion: 2025-11-11
Conditions
Deep Vein Thrombosis Venous Stasis Venous Insufficiency Venous Leg Ulcer Venous Reflux Post Thrombotic Syndrome
Interventions
DEVICE
No Results Yet
NCT03085433 | COMPLETED | NA
393 Participants

Sperm Selection by Microfluidic Separation Improves Embryo Quality

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2017-06-20
Completion: 2021-10-30
Conditions
Sperm DNA Fragmentation Embryo Quality Fertility Disorders Infertility Infertility, Male Infertility Unexplained
Interventions
DEVICE PROCEDURE
NCT03049462 | RECRUITING | PHASE1
100 Participants

The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta3-Adrenergic Receptor Agonists

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2017-03-13
Completion: 2026-09-30
Conditions
Polycystic Ovary Syndrome
Interventions
DRUG OTHER
No Results Yet
NCT03029429 | ACTIVE_NOT_RECRUITING | PHASE2
29 Participants

Theophylline Treatment for Pseudohypoparathyroidism

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2018-09-01
Completion: 2026-12-01
Conditions
Pseudohypoparathyroidism Albright Hereditary Osteodystrophy
Interventions
DRUG
No Results Yet
NCT02951052 | ACTIVE_NOT_RECRUITING | PHASE3
618 Participants

Study Evaluating the Efficacy, Safety, and Tolerability of Switching to Long-acting Cabotegravir Plus Long-acting Rilpivirine From Current Antiretroviral Regimen in Virologically Suppressed HIV-1-infected Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2016-10-28
Completion: 2018-05-29
Conditions
Infection, Human Immunodeficiency Virus HIV Infections
Interventions
DRUG
NCT02938520 | ACTIVE_NOT_RECRUITING | PHASE3
631 Participants
NCT02877706 | RECRUITING
1500 Participants

French Registry of Adult Patients With Immune Thrombocytopenia and Autoimmune Hemolytic Anemia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2013-06-30
Completion: 2026-12-31
Conditions
Immune Thrombocytopenia Autoimmune Hemolytic Anemia
Interventions
OTHER
No Results Yet
NCT02756793 | ACTIVE_NOT_RECRUITING | NA
90 Participants

Stereotactic Radiotherapy for Oligo-Progressive Metastatic Cancer (The STOP Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2016-10-31
Completion: 2022-07-31
Conditions
Metastatic Cancer
Interventions
RADIATION OTHER
No Results Yet
NCT02739295 | COMPLETED | PHASE4
10 Participants

G-CSF in the Treatment of Toxic Epidermal Necrolysis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2016-07-31
Completion: 2023-03-07
Conditions
Stevens - Johnson Syndrome
Interventions
DRUG
No Results Yet
NCT02719951 | COMPLETED | PHASE1
27 Participants

Glutaminergic Transmission in Autism : Molecular Imaging Exploration

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2016-04-30
Completion: 2018-11-15
Conditions
Autism Fragile-X Syndrome (FXS) Healthy Volunteers
Interventions
DRUG OTHER
No Results Yet
NCT02709226 | COMPLETED | PHASE1
17 Participants

Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2016-06-15
Completion: 2022-12-16
Conditions
Astrocytoma, Grade IV Giant Cell Glioblastoma Glioblastoma Multiforme Gliosarcoma
Interventions
RADIATION
No Results Yet
NCT02669225 | COMPLETED | EARLY_PHASE1
22 Participants

Brain Amyloid- Retention During Wakefulness and Following Emergence From Sleep in Healthy People

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2016-05-02
Completion: 2017-01-24
Conditions
Normal Physiology
Interventions
OTHER
No Results Yet
NCT02617966 | RECRUITING
500 Participants

Rod and Cone Mediated Function in Retinal Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2016-03-24
Completion: 2029-12-30
Conditions
Retinal Degeneration Retinitis Pigmentosa Stargardt's Disease
No Results Yet
NCT02610465 | COMPLETED
148 Participants

High Image Matrix CT Reconstruction

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2015-11-09
Completion: 2020-03-27
Conditions
Healthy Subjects Pulmonary-Related Conditions Cardiac-Related Conditions
No Results Yet
NCT02531880 | RECRUITING | PHASE1
40 Participants

Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-11-19
Completion: 2026-07-01
Conditions
Epilepsy
Interventions
DRUG
No Results Yet
NCT02531126 | COMPLETED | PHASE3
877 Participants

An Extension Study of RPC1063 as Therapy for Moderate to Severe Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2015-12-02
Completion: 2024-12-19
Conditions
Ulcerative Colitis
Interventions
DRUG
NCT02527083 | COMPLETED | PHASE4
10 Participants

Influence of Anesthetic Technique on Acute and Chronic Neuropathic Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2015-01-31
Completion: 2019-06-30
Conditions
Acute Pain Chronic Pain Hernia Anesthesia, Intravenous Anesthesia, Intratracheal
Interventions
DRUG
NCT02522611 | NOT_YET_RECRUITING | PHASE1/PHASE2
30 Participants

Periganglionic Resiniferatoxin for the Treatment of Intractable Pain Due to Cancer-induced Bone Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-19
Completion: 2026-12-01
Conditions
Intractable Pain Palliative Care
Interventions
DRUG
No Results Yet
NCT02520609 | COMPLETED
53 Participants

Dynamic Post-Prandial Metabolism in Patients With Non-Alcoholic Fatty Liver Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2015-10-28
Completion: 2020-05-14
Conditions
Liver Disease Fatty Liver
No Results Yet
NCT02390752 | RECRUITING | PHASE1
54 Participants

Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2015-04-29
Completion: 2026-12-31
Conditions
Neurofibroma, Plexiform Precursor Cell Lymphoblastic Leukemia-Lymphoma Leukemia, Promyelocytic, Acute Sarcoma
Interventions
DRUG
No Results Yet
NCT02255435 | ACTIVE_NOT_RECRUITING | PHASE2
172 Participants

A Study to Learn About the Effects and Safety of RTA 408 (Omaveloxolone) in People Aged 16 to 40 With Friedreich's Ataxia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2015-01-31
Completion: 2019-10-31
Conditions
Friedreich Ataxia
Interventions
DRUG
NCT02208375 | ACTIVE_NOT_RECRUITING | PHASE1
159 Participants

mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2014-11-11
Completion: 2026-06-30
Conditions
BRCA1 Mutation Carrier BRCA2 Mutation Carrier Endometrial Adenocarcinoma Estrogen Receptor Negative HER2/Neu Negative High Grade Ovarian Serous Adenocarcinoma Progesterone Receptor Negative Recurrent Breast Carcinoma Recurrent Fallopian Tube Carcinoma Recurrent Ovarian Carcinoma Recurrent Primary Peritoneal Carcinoma Recurrent Uterine Corpus Carcinoma Stage III Uterine Corpus Cancer AJCC v7 Stage IV Breast Cancer AJCC v6 and v7 Stage IV Uterine Corpus Cancer AJCC v7 Triple-Negative Breast Carcinoma
Interventions
DRUG OTHER
No Results Yet
NCT02108028 | COMPLETED
272 Participants

Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2014-04-03
Completion: 2023-08-16
Conditions
HIV Cancer Chronic Granulomatous Disease Dock 8 Deficiency
No Results Yet
NCT01934660 | COMPLETED
150 Participants

Links Between Inflammation and Cardiometabolic Diseases

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2013-12-02
Completion: 2022-08-03
Conditions
Diabetes Mellitus Cardiovascular Disease Healthy Volunteer Inflammation
Interventions
DRUG
No Results Yet
NCT01851447 | ACTIVE_NOT_RECRUITING
11 Participants

Skeletal Muscle Biomarkers in People With Fragile Sarcolemmal Muscular Dystrophy

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2014-11-03
Completion: 2025-12-31
Conditions
Genetic Disorder
No Results Yet
NCT01809691 | COMPLETED | PHASE3
1313 Participants

S1216, Phase III ADT+TAK-700 vs. ADT+Bicalutamide for Metastatic Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2013-03-08
Completion: 2022-03-08
Conditions
Prostate Cancer
Interventions
DRUG
NCT01778504 | RECRUITING
1000 Participants

Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2012-12-27
Completion: 2029-02-20
Conditions
Neuropsychiatric Disorder Neurological Disorder Neurodevelopmental Disorder Sleep
No Results Yet
NCT01734369 | COMPLETED
37 Participants

Environmental Risk Factors for Myositis in Military Personnel

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2014-03-13
Completion: 2021-10-31
Conditions
Dermatomyositis Adult Polymyositis Inclusion Body Myositis Myositis
No Results Yet
NCT01643954 | ACTIVE_NOT_RECRUITING | NA
1531 Participants

Retrospective/Prospective Analysis of Surgical Outcomes of Robotic Prostatectomy at The James

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2008-09-23
Completion: 2027-07-31
Conditions
Prostate Cancer
Interventions
PROCEDURE
No Results Yet
NCT01617395 | COMPLETED
181 Participants

Relating Genetic and Environmental Risk Scores to Multiple Sclerosis Susceptibility

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2012-08-15
Conditions
Multiple Sclerosis
No Results Yet
NCT01571752 | COMPLETED
1651 Participants

Health Outcomes by Neighborhood - Baltimore

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2012-07-17
Conditions
Stigma Activity Space Social Networks HIV Status Drug Abuse/Dependence
No Results Yet
NCT01568658 | RECRUITING
9300 Participants

Genetic and Physical Study of Childhood Nerve and Muscle Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2012-03-20
Conditions
Muscular Dystrophies Muscle Myopathies Hereditary Spastic Paraplegias Inherited Neuropathies Inherited Neuromuscular Conditions
No Results Yet
NCT01498276 | COMPLETED
310 Participants

Family Genetics Health Education and Healthy Behaviors

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2012-01-03
Conditions
Diabetes Cancer Heart Disease
No Results Yet
NCT01445288 | COMPLETED
76 Participants

Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2006-12-05
Conditions
Diffuse Intrinsic Pontine Glioma PNET Ependymoma Germinoma Medulloblastoma
No Results Yet
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