High Image Matrix CT Reconstruction

NCT ID: NCT02610465

Last Updated: 2025-12-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

148 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-11-09

Study Completion Date

2020-03-27

Brief Summary

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Background:

Computed Tomography (CT) scans make detailed pictures of the body in seconds. CT scans make pictures by passing x-rays through a person. CT scans are common. In 2011, around 85.3 million of them occurred in the United States. Researchers think CT images can be made better using new techniques. Higher resolution images can be derived from the original scan.

Objective:

To learn if new ways of obtaining and processing pictures of the body from a regular CT scan can produce images with higher resolution (pixels) and more information than standard methods.

Eligibility:

People ages 18 and older who are scheduled to have a CT scan and are not pregnant

Design:

Participants will be screened with a review of their medical records.

Participants will have their scheduled CT scan.

The CT scanner used in this study provides enhanced images of inside the body. Researchers may use the CT scanner in a research mode to test and improve the pictures.

Images from the CT scan will be reviewed.

Any clinical findings from the CT test will be shared with the participant s doctor.

Participants will continue to receive their medical care from their regular doctor.

The CT images will be entered into an NIH research database. In the future, they may be used for research purposes.

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Detailed Description

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Computed Tomography (CT) images the body. Different methods of creating CT pictures are avilable on a research basis that enables higher resolution imaging using the same aquisition. The purpose of this research study is to learn wheteher these new high resolution images derived from the original CT scan provide similar or perhaps more information than the current standard clinical method.

Conditions

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Healthy Subjects Pulmonary-Related Conditions Cardiac-Related Conditions

Keywords

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Computed Tomography Image Reconstruction Iterative Reconstruction Natural History

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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1

Computed Tomography (CT) images

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Clinical indication for CT
* Age equal to or greater than 18 years
* Able to understand and willing to sign the Informed Consent Form

Exclusion Criteria

-Pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Heart, Lung, and Blood Institute (NHLBI)

NIH

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Marcus Y Chen, M.D.

Role: PRINCIPAL_INVESTIGATOR

National Heart, Lung, and Blood Institute (NHLBI)

Locations

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National Institutes of Health Clinical Center

Bethesda, Maryland, United States

Site Status

Countries

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United States

Related Links

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Other Identifiers

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16-H-0019

Identifier Type: -

Identifier Source: secondary_id

160019

Identifier Type: -

Identifier Source: org_study_id