The Aging Brain ANSWERS Program

NCT ID: NCT03397667

Last Updated: 2025-12-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

236 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-08-01

Study Completion Date

2023-05-31

Brief Summary

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This study will test the effectiveness of an intervention for Veterans diagnosed with Alzheimer's Disease (AD) or Traumatic Brain Injury (TBI) and the burden on their informal (family/friend) caregiver.

Detailed Description

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The majority of people with Alzheimer's (AD) and Traumatic brain Injury (TBI) are cared for in primary care settings and receive significant amounts of care and assistance in activities of daily living from family members or friends.

The ABC ANSWERS intervention will incorporate and integrate the common features of an evidence-based collaborative care model for brain care, while also attending to the implementation barriers of delivering care and skills to dyads of patients with AD and TBI and their family caregivers.

The study team will conduct a 1-year randomized control trial (RCT) designed to improve the Quality of Life (QoL) of Veterans with AD and TBI, and their family caregivers, and decrease their family caregivers' burden. The dyads in the intervention group will receive primary care plus ABC ANSWERS. The control group will receive primary care.

Conditions

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Traumatic Brain Injury Alzheimer Disease Veterans Family Caregivers Caregiver Burden Quality of Life

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

SINGLE

Outcome Assessors
The outcomes assessor is blinded to which arm a dyad is enrolled.

Study Groups

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Control

Primary Care

Group Type OTHER

Control

Intervention Type OTHER

Primary Care as usual

Intervention

Primary Care plus ABC ANSWERS intervention

Group Type EXPERIMENTAL

ABC ANSWERS

Intervention Type OTHER

Primary Care plus ABC ANSWERS

Interventions

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ABC ANSWERS

Primary Care plus ABC ANSWERS

Intervention Type OTHER

Control

Primary Care as usual

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Veterans: 1)Diagnosis of AD or TBI 2) Receives Primary Care from Veterans Administration Medical Center (VAMC)
* Caregivers: 1) Primary caregiver (family or friend) of a Veteran with AD or TBI 2) Plans to provide care for 1 year or longer
* Both: 1) Over 18 years of age 2) Speak and understand English 3) access to telephone

Exclusion Criteria

* Veterans: 1) Resides in nursing home or long term care facility 2) currently receiving care in GRACE clinic 3) Enrolled in ANSWERS-VA research study
* Caregivers: 1) Does not consider him/herself a caregiver for Veteran 2) Serious medical illness limiting ability to participate
* Both: Unable to contact within 10 calls Age \< 18 years Either caregiver or Veteran denies that they have AD or a TBI Either the caregiver or Veteran does not want to participate Not fluent in the English language Difficulty hearing or talking by telephone Has a terminal illness (e.g., cancer, end of life condition with decreased life expectancy, renal failure requiring dialysis) History of hospitalization for alcohol or drug abuse History of severe mental illness (e.g., suicidal tendencies, severe untreated depression or bipolar disorder, or schizophrenia) Prisoner or on house arrest
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Richard L. Roudebush VA Medical Center

FED

Sponsor Role collaborator

Cleveland State University

OTHER

Sponsor Role collaborator

Indiana University

OTHER

Sponsor Role lead

Responsible Party

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Nicole R. Fowler, PhD

Scientist, Indiana University Center for Aging Research

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Richard L. Roudebush VAMC

Indianapolis, Indiana, United States

Site Status

Countries

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United States

References

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Carnahan JL, Judge KS, Daggy JK, Slaven JE, Coleman N, Fortier EL, Suelzer C, Fowler NR. Supporting caregivers of veterans with Alzheimer's disease and traumatic brain injury: study protocol for a randomized controlled trial. Trials. 2020 Apr 19;21(1):340. doi: 10.1186/s13063-020-4199-1.

Reference Type DERIVED
PMID: 32306982 (View on PubMed)

Other Identifiers

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AZ160032

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

#1706902669

Identifier Type: -

Identifier Source: org_study_id