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Clinical Trials

Showing trials with last updates posted in 2025.

NCT03696017 | RECRUITING
120 Participants

Opioid/Benzodiazepine Polydrug Abuse

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2019-02-08
Completion: 2026-12-31
Conditions
Polysubstance Abuse
Interventions
OTHER
No Results Yet
NCT03694457 | COMPLETED | NA
90 Participants

Comparison Between Anterior Approach (Deltopectoral) and Lateral Approach (Deltoid Splitting) in Shoulder Reverse Arthroplasty for Proximal Humerus Fracture

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2018-11-26
Completion: 2023-12-31
Conditions
Humeral Fracture Aged Patient Reversed Total Shoulder Arthroplasty Surgical Approach
Interventions
PROCEDURE
No Results Yet
NCT03663348 | RECRUITING
500 Participants

Registry of Patients With Takotsubo Syndrome

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2009-09-11
Completion: 2028-09-01
Conditions
Takotsubo Cardiomyopathy Broken Heart Syndrome Tako-tsubo Cardiomyopathy
No Results Yet
NCT03650764 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
43 Participants

Ramucirumab + Pembrolizumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2019-05-29
Completion: 2026-06-30
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
DRUG OTHER PROCEDURE
No Results Yet
NCT03647878 | ACTIVE_NOT_RECRUITING
224 Participants

Study of Cabozantinib as Monotherapy or in Combination With Nivolumab in Patients With Advanced or Metastatic Renal Cell Carcinoma Under Real-life Clinical Setting in 1st Line Treatment.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2018-09-24
Completion: 2027-09-30
Conditions
Advanced Renal Cell Carcinoma Metastatic Renal Cell Carcinoma
No Results Yet
NCT03630536 | ACTIVE_NOT_RECRUITING
28 Participants

TFE Renal Cell Carcinoma: A Prospective Registry and Translational Research Initiative

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2018-08-12
Completion: 2026-06-30
Conditions
Renal Cell Carcinoma
No Results Yet
NCT03615794 | COMPLETED
300 Participants

A Study of Pregnant and Postpartum Women With and Without Mood Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2017-10-01
Completion: 2024-01-31
Conditions
Bipolar Disorder Major Depressive Disorder Postpartum Depression Postpartum Psychosis
No Results Yet
NCT03609944 | COMPLETED | NA
181 Participants

SpHincterotomy for Acute Recurrent Pancreatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2018-09-27
Completion: 2025-02-28
Conditions
Pancreatitis Pancreas Divisum Pancreatitis, Acute Pancreatitis Idiopathic Pancreas Inflamed
Interventions
PROCEDURE
Results Available
NCT03605524 | COMPLETED | NA
150 Participants

Olfactory Training and Emotional State

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2018-08-28
Completion: 2023-06-27
Conditions
Depressive Symptoms Depressive Disorder, Major
Interventions
OTHER
No Results Yet
NCT03574363 | COMPLETED | PHASE2
162 Participants

Phase 2b Study of KBP-5074 in Subjects With Uncontrolled Hypertension and Advanced Chronic Kidney Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2018-04-25
Completion: 2020-08-05
Conditions
Chronic Kidney Diseases Hypertension
Interventions
DRUG
Results Available
NCT03554083 | ACTIVE_NOT_RECRUITING | PHASE2
59 Participants

Vemurafenib, Cobimetinib, Atezolizumab, and Tiragolumab in Treating Patients With High-Risk Stage III Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2018-10-05
Completion: 2027-11-30
Conditions
Clinical Stage III Cutaneous Melanoma AJCC v8 Pathologic Stage III Cutaneous Melanoma AJCC v8 Pathologic Stage IIIA Cutaneous Melanoma AJCC v8 Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 Pathologic Stage IIID Cutaneous Melanoma AJCC v8
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT03516279 | ACTIVE_NOT_RECRUITING | PHASE2
40 Participants

Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2019-06-26
Completion: 2028-08-31
Conditions
Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive Minimal Residual Disease
Interventions
DRUG OTHER BIOLOGICAL
No Results Yet
NCT03481010 | RECRUITING | NA
204 Participants

Periacetabular Osteotomy With and Without Arthroscopic Management of Central Compartment Pathology

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2018-04-04
Completion: 2030-07-31
Conditions
Hip Dysplasia
Interventions
PROCEDURE
No Results Yet
NCT03454568 | COMPLETED
110 Participants

The Patients' Experience After Stem Cell Transplant

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2017-09-01
Completion: 2022-11-11
Conditions
Stem Cell Transplant Complications
No Results Yet
NCT03443492 | COMPLETED | PHASE2
130 Participants

SLOG vs mFOLFIRINOX as the First-line Treatment in Locally Advanced Uncresectable or Metastatic Pancreatic Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2018-03-26
Completion: 2019-11-30
Conditions
Locally Advanced or Metastatic Pancreatic Cancer
Interventions
DRUG
No Results Yet
NCT03398135 | ACTIVE_NOT_RECRUITING | PHASE3
1242 Participants

A Study to Assess the Efficacy and Safety of Risankizumab in Participants With Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2018-08-28
Completion: 2028-09-30
Conditions
Ulcerative Colitis (UC)
Interventions
DRUG
No Results Yet
NCT03395197 | ACTIVE_NOT_RECRUITING | PHASE3
1054 Participants

Talazoparib + Enzalutamide vs. Enzalutamide Monotherapy in mCRPC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-12-18
Completion: 2022-10-03
Conditions
mCRPC
Interventions
DRUG
Results Available
NCT03383016 | ACTIVE_NOT_RECRUITING
2053 Participants

Diet, Physical Activity and Related Candidate Biomarkers in Relation to Prostate Cancer Risk (BIOCaPPE)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2013-06-20
Completion: 2022-09-23
Conditions
Epidemiology Prostate Cancer
Interventions
OTHER DIAGNOSTIC_TEST
No Results Yet
NCT03345420 | COMPLETED | PHASE2
102 Participants

Hypofractionated Radiation Therapy in Treating Patients With Stage 0-IIB Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-12-12
Completion: 2022-08-30
Conditions
Stage II Breast Cancer Stage IIA Breast Cancer Stage IIB Breast Cancer Ductal Breast Carcinoma In Situ Invasive Breast Carcinoma Stage 0 Breast Cancer Stage I Breast Cancer Stage IA Breast Cancer Stage IB Breast Cancer
Interventions
RADIATION
Results Available
NCT03292458 | COMPLETED | PHASE2/PHASE3
117 Participants

Sodium Oxybate in Spasmodic Dysphonia and Voice Tremor

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2018-01-22
Completion: 2021-12-29
Conditions
Spasmodic Dysphonia Voice Tremor
Interventions
DRUG
Results Available
NCT03291470 | ACTIVE_NOT_RECRUITING | PHASE3
531 Participants

Study to Determine the Efficacy and Safety of TG-C in Subjects With Kellgren/Lawrence Grade 2 or 3 OA of the Knee

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2021-12-09
Completion: 2024-03-06
Conditions
Degenerative Osteoarthritis
Interventions
BIOLOGICAL
No Results Yet
NCT03291067 | COMPLETED | PHASE2
375 Participants

MT-8554 for Reduction of Vasomotor Symptoms in Postmenopausal Women

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-10-09
Completion: 2018-10-19
Conditions
Menopause Hot Flashes
Interventions
DRUG
Results Available
NCT03203330 | ACTIVE_NOT_RECRUITING | PHASE3
535 Participants

A Study to Determine the Safety and Efficacy of TG-C in Subjects With Kellgren and Lawrence Grade 2 or 3 OA of the Knee

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2018-10-30
Completion: 2024-07-10
Conditions
Degenerative Osteoarthritis
Interventions
BIOLOGICAL
No Results Yet
NCT03199885 | COMPLETED | PHASE3
190 Participants

Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2019-04-05
Completion: 2024-04-30
Conditions
Metastatic Breast Adenocarcinoma Metastatic HER2-Positive Breast Carcinoma Recurrent Breast Adenocarcinoma Recurrent HER2-Positive Breast Carcinoma Stage III Breast Cancer AJCC v7 Stage IV Breast Cancer AJCC v6 and v7 Unresectable Breast Carcinoma Unresectable HER2-Positive Breast Carcinoma
Interventions
DRUG PROCEDURE BIOLOGICAL OTHER
Results Available
NCT03192891 | COMPLETED
2349 Participants

Stress CMR Perfusion Imaging in the United States (SPINS) Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2016-12-01
Completion: 2019-11-30
Conditions
Myocardial Ischemia
Interventions
DIAGNOSTIC_TEST
Results Available
NCT03115333 | ACTIVE_NOT_RECRUITING | NA
146 Participants

DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-07-25
Completion: 2025-12-31
Conditions
Gliosarcoma Recurrent Glioblastoma
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT03072927 | RECRUITING
8000 Participants

MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2017-03-10
Completion: 2026-12-31
Conditions
Lumbar Spinal Stenosis
Interventions
DEVICE
No Results Yet
NCT03036930 | ACTIVE_NOT_RECRUITING | PHASE2
51 Participants

Preventive Human Papillomavirus (HPV) Vaccine Trial in Kidney Transplant Recipients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-06-23
Completion: 2024-03-04
Conditions
Human Papillomavirus Infection Human Papillomavirus-Related Carcinoma
Interventions
PROCEDURE OTHER BIOLOGICAL
Results Available
NCT03006068 | ACTIVE_NOT_RECRUITING | PHASE3
950 Participants

A Study to Evaluate the Long-Term Safety and Efficacy of Upadacitinib (ABT-494) in Participants With Ulcerative Colitis (UC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-01-31
Completion: 2027-07-31
Conditions
Ulcerative Colitis (UC)
Interventions
DRUG
No Results Yet
NCT02990286 | COMPLETED | PHASE3
122 Participants

Evaluation of Efficacy and Safety of Rituximab With Mycophenolate Mofetil in Patients With Interstitial Lung Diseases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-01-20
Completion: 2019-07-24
Conditions
Lung Disease, Interstitial
Interventions
DRUG
No Results Yet
NCT02975310 | RECRUITING | NA
140 Participants

In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-04-11
Completion: 2025-12-31
Conditions
Sinusitis Nasal Polyps
Interventions
PROCEDURE OTHER
No Results Yet
NCT02917473 | COMPLETED | NA
420 Participants

Comparison of Two Strategies for Counseling Skin Examination and Sun Protection in First-degree Relatives of Patients With Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-12-13
Completion: 2019-04-26
Conditions
Melanoma Screening
Interventions
BEHAVIORAL
No Results Yet
NCT02860000 | ACTIVE_NOT_RECRUITING | PHASE2
96 Participants

Alisertib With or Without Fulvestrant in Treating Patients With Locally Advanced or Metastatic, Endocrine-Resistant Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-07-06
Completion: 2022-01-10
Conditions
Estrogen Receptor Status HER2/Neu Negative Invasive Breast Carcinoma Postmenopausal Stage III Breast Cancer Stage IIIA Breast Cancer Stage IIIB Breast Cancer Stage IIIC Breast Cancer Stage IV Breast Cancer
Interventions
DRUG OTHER
Results Available
NCT02837237 | COMPLETED | PHASE1
11 Participants

Safety, Tolerability, and Pharmacokinetics of KBP-5074 Following Oral Administration in Chronic Kidney Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2016-07-13
Completion: 2016-12-20
Conditions
Chronic Kidney Disease
Interventions
DRUG
Results Available
NCT02789839 | COMPLETED | NA
102 Participants

Analyses of Bone Marrow and Blood Samples From Healthy Volunteers: Focus on the redOx Metabolism

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2016-08-31
Completion: 2017-08-31
Conditions
redOx Metabolism
Interventions
PROCEDURE
No Results Yet
NCT02730039 | ACTIVE_NOT_RECRUITING
350 Participants

Meaning-Centered Psychotherapy Training for Cancer Care Providers

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2015-12-11
Completion: 2026-12-11
Conditions
Cancer Care Providers
Interventions
BEHAVIORAL
No Results Yet
NCT02727972 | COMPLETED | NA
180 Participants

Examination of Glutamate and mGluR5 in Psychiatric Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2012-02-21
Completion: 2022-01-13
Conditions
Major Depressive Disorder Post-Traumatic Stress Disorder Bipolar Disorder
Interventions
BEHAVIORAL OTHER RADIATION
No Results Yet
NCT02664545 | ACTIVE_NOT_RECRUITING | NA
100 Participants

Bridge-Enhanced ACL Repair vs ACL Reconstruction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2016-04-30
Completion: 2019-06-19
Conditions
Anterior Cruciate Ligament Tear
Interventions
DEVICE PROCEDURE
Results Available
NCT02570620 | COMPLETED | NA
342 Participants

Contribution of Ultrasonography in the Evaluation of Cervical Induction-delivery Time

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2010-09-30
Completion: 2014-03-31
Conditions
Delivery Uterine Birth; Induced
Interventions
DEVICE
No Results Yet
NCT02533206 | ACTIVE_NOT_RECRUITING | NA
20 Participants

Pilot Study of The EPIC Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2015-08-31
Completion: 2022-12-31
Conditions
Sinusitis Nasal Polyps
Interventions
PROCEDURE
No Results Yet
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