Periacetabular Osteotomy With and Without Arthroscopic Management of Central Compartment Pathology
NCT ID: NCT03481010
Last Updated: 2025-12-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
204 participants
INTERVENTIONAL
2018-04-04
2030-12-31
Brief Summary
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This research project will randomize patients to receive either a PAO alone, or a PAO and a hip arthroscopy at the same time.
Detailed Description
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The periacetabular osteotomy (PAO) is a surgical procedure that reorients the acetabulum to reduce the stresses inside the hip joint. The PAO is very effective at improving symptoms and quality of life. However, some patients may have residual symptoms.
Frequently, people with hip dysplasia will have an MRI done before their surgery, which helps to identify other the abnormalities inside their hip joint (e.g., labral tears). These abnormalities inside the joint cannot easily be addressed through PAO alone, however they can be addressed with hip arthroscopy. Hip arthroscopy is a separate minimally invasive surgical procedure that allows the surgeon to access the inside of the hip joint with a small camera and address any abnormalities.
At present, it is not clear whether performing a hip arthroscopy at the same time as a PAO improves patient outcomes after surgery compared to a PAO alone.
This research project will randomize patients to receive either a PAO alone, or a PAO and a hip arthroscopy at the same time. Patients will be followed for 2 years after surgery. Symptomatic differences between the two patient groups will be assessed to determine added benefit of the hip arthroscopy.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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PAO with hip arthroscopy
Patient's in the "Scope PAO" group have been diagnosed with hip dysplasia and a decision has been made between the patient and the surgeon that the best way to treat the hip problems is with surgery. Patient's in the "Scope-PAO" group have been randomized to receive a periacetabular osteotomy with a hip arthroscopy.
PAO with hip arthroscopy
Participants who are randomized to the Scope-PAO group will receive central compartment hip arthroscopy in addition to the PAO.
PAO without hip arthroscopy
Patient's in the "PAO-only" group have been diagnosed with hip dysplasia and a decision has been made between the patient and the surgeon that the best way to treat the hip problems is with surgery. Patient's in the "PAO-only" group have been randomized to receive a periacetabular osteotomy only.
PAO without hip arthroscopy
Participants who are randomized to the "PAO-only" group will receive a Bernese Periacetabular Osteotomy (PAO) for treatment of hip dysplasia.
Interventions
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PAO with hip arthroscopy
Participants who are randomized to the Scope-PAO group will receive central compartment hip arthroscopy in addition to the PAO.
PAO without hip arthroscopy
Participants who are randomized to the "PAO-only" group will receive a Bernese Periacetabular Osteotomy (PAO) for treatment of hip dysplasia.
Eligibility Criteria
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Inclusion Criteria
* Pre-Operative MRI at 3T and/or gadolinium MR arthrogram
* Age, 16-50 years old
* Patient capable of giving informed consent
Exclusion Criteria
* Prior hip arthroplasty surgery on either side
* Radiographic evidence of arthritis (i.e. Tönnis grade =2)
* Known connective tissue disorder (e.g. Ehlers-Danlos Syndrome, etc.)
* Known neuromuscular disorder (e.g. Cerebral Palsy, Spina bifida, etc.)
* Known skeletal dysplasia (e.g. Achondroplasia, Multiple Epiphyseal Dysplasia, etc.)
* Cognitive impairment that prevents accurate completion of patient-reported outcome questionnaires.
* Patient unable/unwilling to complete all required follow-up visits
* Concurrent proximal femoral osteotomy and/or surgical hip dislocation
16 Years
50 Years
ALL
No
Sponsors
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Ottawa Hospital Research Institute
OTHER
Responsible Party
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Principal Investigators
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Geoffrey Wilkin, MD
Role: PRINCIPAL_INVESTIGATOR
The Ottawa Hospital Research Institute
Locations
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Northwestern University
Chicago, Illinois, United States
William Beaumont Hospital
Royal Oak, Michigan, United States
The Washington University
St Louis, Missouri, United States
Hospital for Special Surgery
New York, New York, United States
Children's Hospital of Eastern Ontario
Ottawa, Ontario, Canada
Ottawa Hospital Research Institute
Ottawa, Ontario, Canada
CHU de Québec - Université Laval
Québec, , Canada
Countries
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Central Contacts
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Facility Contacts
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Michael Stover, MD
Role: primary
Ira Zaltz, MD
Role: primary
John C. Clohisy, MD
Role: primary
Ernest Sink, MD
Role: primary
Kevin Smit, MD
Role: primary
Geoffrey Wilkin, MD
Role: primary
Research Team
Role: backup
Etienne Belzile, MD
Role: primary
References
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Wilkin GP, Poitras S, Clohisy J, Belzile E, Zaltz I, Grammatopoulos G, Melkus G, Rakhra K, Ramsay T, Thavorn K, Beaule PE. Periacetabular osteotomy with or without arthroscopic management in patients with hip dysplasia: study protocol for a multicenter randomized controlled trial. Trials. 2020 Aug 18;21(1):725. doi: 10.1186/s13063-020-04592-9.
Other Identifiers
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20170796
Identifier Type: -
Identifier Source: org_study_id