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Clinical Trials

Showing trials with last updates posted in 2025.

NCT03395197 | ACTIVE_NOT_RECRUITING | PHASE3
1054 Participants

Talazoparib + Enzalutamide vs. Enzalutamide Monotherapy in mCRPC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-12-18
Completion: 2022-10-03
Conditions
mCRPC
Interventions
DRUG
Results Available
NCT03383016 | ACTIVE_NOT_RECRUITING
2053 Participants

Diet, Physical Activity and Related Candidate Biomarkers in Relation to Prostate Cancer Risk (BIOCaPPE)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2013-06-20
Completion: 2022-09-23
Conditions
Epidemiology Prostate Cancer
Interventions
OTHER DIAGNOSTIC_TEST
No Results Yet
NCT03345420 | COMPLETED | PHASE2
102 Participants

Hypofractionated Radiation Therapy in Treating Patients With Stage 0-IIB Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-12-12
Completion: 2022-08-30
Conditions
Stage II Breast Cancer Stage IIA Breast Cancer Stage IIB Breast Cancer Ductal Breast Carcinoma In Situ Invasive Breast Carcinoma Stage 0 Breast Cancer Stage I Breast Cancer Stage IA Breast Cancer Stage IB Breast Cancer
Interventions
RADIATION
Results Available
NCT03292458 | COMPLETED | PHASE2/PHASE3
117 Participants

Sodium Oxybate in Spasmodic Dysphonia and Voice Tremor

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2018-01-22
Completion: 2021-12-29
Conditions
Spasmodic Dysphonia Voice Tremor
Interventions
DRUG
Results Available
NCT03291470 | ACTIVE_NOT_RECRUITING | PHASE3
531 Participants

Study to Determine the Efficacy and Safety of TG-C in Subjects With Kellgren/Lawrence Grade 2 or 3 OA of the Knee

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2021-12-09
Completion: 2024-03-06
Conditions
Degenerative Osteoarthritis
Interventions
BIOLOGICAL
No Results Yet
NCT03291067 | COMPLETED | PHASE2
375 Participants

MT-8554 for Reduction of Vasomotor Symptoms in Postmenopausal Women

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-10-09
Completion: 2018-10-19
Conditions
Menopause Hot Flashes
Interventions
DRUG
Results Available
NCT03203330 | ACTIVE_NOT_RECRUITING | PHASE3
535 Participants

A Study to Determine the Safety and Efficacy of TG-C in Subjects With Kellgren and Lawrence Grade 2 or 3 OA of the Knee

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2018-10-30
Completion: 2024-07-10
Conditions
Degenerative Osteoarthritis
Interventions
BIOLOGICAL
No Results Yet
NCT03199885 | COMPLETED | PHASE3
190 Participants

Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2019-04-05
Completion: 2024-04-30
Conditions
Metastatic Breast Adenocarcinoma Metastatic HER2-Positive Breast Carcinoma Recurrent Breast Adenocarcinoma Recurrent HER2-Positive Breast Carcinoma Stage III Breast Cancer AJCC v7 Stage IV Breast Cancer AJCC v6 and v7 Unresectable Breast Carcinoma Unresectable HER2-Positive Breast Carcinoma
Interventions
DRUG PROCEDURE BIOLOGICAL OTHER
Results Available
NCT03192891 | COMPLETED
2349 Participants

Stress CMR Perfusion Imaging in the United States (SPINS) Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2016-12-01
Completion: 2019-11-30
Conditions
Myocardial Ischemia
Interventions
DIAGNOSTIC_TEST
Results Available
NCT03115333 | ACTIVE_NOT_RECRUITING | NA
146 Participants

DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-07-25
Completion: 2025-12-31
Conditions
Gliosarcoma Recurrent Glioblastoma
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT03072927 | RECRUITING
8000 Participants

MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2017-03-10
Completion: 2026-12-31
Conditions
Lumbar Spinal Stenosis
Interventions
DEVICE
No Results Yet
NCT03036930 | ACTIVE_NOT_RECRUITING | PHASE2
51 Participants

Preventive Human Papillomavirus (HPV) Vaccine Trial in Kidney Transplant Recipients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-06-23
Completion: 2024-03-04
Conditions
Human Papillomavirus Infection Human Papillomavirus-Related Carcinoma
Interventions
PROCEDURE OTHER BIOLOGICAL
Results Available
NCT02990286 | COMPLETED | PHASE3
122 Participants

Evaluation of Efficacy and Safety of Rituximab With Mycophenolate Mofetil in Patients With Interstitial Lung Diseases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-01-20
Completion: 2019-07-24
Conditions
Lung Disease, Interstitial
Interventions
DRUG
No Results Yet
NCT02975310 | RECRUITING | NA
140 Participants

In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-04-11
Completion: 2025-12-31
Conditions
Sinusitis Nasal Polyps
Interventions
PROCEDURE OTHER
No Results Yet
NCT02917473 | COMPLETED | NA
420 Participants

Comparison of Two Strategies for Counseling Skin Examination and Sun Protection in First-degree Relatives of Patients With Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-12-13
Completion: 2019-04-26
Conditions
Melanoma Screening
Interventions
BEHAVIORAL
No Results Yet
NCT02860000 | ACTIVE_NOT_RECRUITING | PHASE2
96 Participants

Alisertib With or Without Fulvestrant in Treating Patients With Locally Advanced or Metastatic, Endocrine-Resistant Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-07-06
Completion: 2022-01-10
Conditions
Estrogen Receptor Status HER2/Neu Negative Invasive Breast Carcinoma Postmenopausal Stage III Breast Cancer Stage IIIA Breast Cancer Stage IIIB Breast Cancer Stage IIIC Breast Cancer Stage IV Breast Cancer
Interventions
DRUG OTHER
Results Available
NCT02837237 | COMPLETED | PHASE1
11 Participants

Safety, Tolerability, and Pharmacokinetics of KBP-5074 Following Oral Administration in Chronic Kidney Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2016-07-13
Completion: 2016-12-20
Conditions
Chronic Kidney Disease
Interventions
DRUG
Results Available
NCT02789839 | COMPLETED | NA
102 Participants

Analyses of Bone Marrow and Blood Samples From Healthy Volunteers: Focus on the redOx Metabolism

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2016-08-31
Completion: 2017-08-31
Conditions
redOx Metabolism
Interventions
PROCEDURE
No Results Yet
NCT02730039 | ACTIVE_NOT_RECRUITING
350 Participants

Meaning-Centered Psychotherapy Training for Cancer Care Providers

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2015-12-11
Completion: 2026-12-11
Conditions
Cancer Care Providers
Interventions
BEHAVIORAL
No Results Yet
NCT02727972 | COMPLETED | NA
180 Participants

Examination of Glutamate and mGluR5 in Psychiatric Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2012-02-21
Completion: 2022-01-13
Conditions
Major Depressive Disorder Post-Traumatic Stress Disorder Bipolar Disorder
Interventions
BEHAVIORAL OTHER RADIATION
No Results Yet
NCT02664545 | ACTIVE_NOT_RECRUITING | NA
100 Participants

Bridge-Enhanced ACL Repair vs ACL Reconstruction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2016-04-30
Completion: 2019-06-19
Conditions
Anterior Cruciate Ligament Tear
Interventions
DEVICE PROCEDURE
Results Available
NCT02570620 | COMPLETED | NA
342 Participants

Contribution of Ultrasonography in the Evaluation of Cervical Induction-delivery Time

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2010-09-30
Completion: 2014-03-31
Conditions
Delivery Uterine Birth; Induced
Interventions
DEVICE
No Results Yet
NCT02533206 | ACTIVE_NOT_RECRUITING | NA
20 Participants

Pilot Study of The EPIC Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2015-08-31
Completion: 2022-12-31
Conditions
Sinusitis Nasal Polyps
Interventions
PROCEDURE
No Results Yet
NCT02455284 | COMPLETED | NA
134 Participants

In Vivo and ex Vivo Validation of MR Tractography of Brain White Matter Tracts - FIBRATLAS II-III

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2015-10-31
Completion: 2021-02-28
Conditions
Neurological Diseases
Interventions
DEVICE
No Results Yet
NCT02285192 | ACTIVE_NOT_RECRUITING | PHASE1
42 Participants

Positron Lymphography Via Intracervical 18F-FDG Injection for Pre-surgical Lymphatic Mapping in Stage IB1 Cervical Cancer and High-grade Endometrial Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2014-11-30
Completion: 2026-11-30
Conditions
Cervical Cancer Endometrial Cancer
Interventions
RADIATION DEVICE
No Results Yet
NCT02276885 | ACTIVE_NOT_RECRUITING | NA
284 Participants

Prone Partial Breast Irradiation (PBI): a Prospective Randomized Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2014-10-28
Completion: 2023-12-07
Conditions
Breast Cancer
Interventions
RADIATION
Results Available
NCT02270814 | ACTIVE_NOT_RECRUITING | PHASE2
74 Participants

Cisplatin, Nab-Paclitaxel, and Cetuximab (CACTUX) in Patients With Incurable Head and Neck Squamous Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2015-02-02
Completion: 2026-06-30
Conditions
Head and Neck Cancer Head and Neck Squamous Cell Carcinoma Cancer of the Head and Neck
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT02229123 | COMPLETED | PHASE2
18 Participants

Levetiracetam Treatment of Neonatal Seizures: Safety and Efficacy Phase II Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2018-02-27
Completion: 2022-02-23
Conditions
Neonatal Seizures
Interventions
DRUG
No Results Yet
NCT02131805 | COMPLETED | NA
36 Participants

Electronic Skin Surface Brachytherapy for Cutaneous Basal Cell and Squamous Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2014-05-31
Completion: 2025-12-23
Conditions
Cutaneous Basal Cell Squamous Cell Carcinoma
Interventions
RADIATION BEHAVIORAL
No Results Yet
NCT02122107 | ACTIVE_NOT_RECRUITING
499 Participants

Cognition in Older Breast Cancer Survivors: Treatment Exposure, APOE and Smoking History

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2014-04-08
Completion: 2026-04-30
Conditions
Breast Cancer Survivors
No Results Yet
NCT02112617 | RECRUITING | NA
30 Participants

Phase II Study of Proton Radiation Therapy for Neuroblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2014-06-30
Completion: 2026-06-30
Conditions
Neuroblastoma Ganglioneuroblastoma
Interventions
RADIATION
No Results Yet
NCT02051218 | ACTIVE_NOT_RECRUITING | PHASE3
1380 Participants

Prevention of Symptomatic Skeletal Events With Denosumab Administered Every 4 Weeks Versus Every 12 Weeks

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2014-07-16
Completion: 2026-06-30
Conditions
Metastatic Breast Cancer Metastatic Prostate Cancer Bone Metastases
Interventions
DRUG
No Results Yet
NCT01983410 | ACTIVE_NOT_RECRUITING
600 Participants

A Registry for BRCA Mutation Carriers With Pancreatic Ductal Adenocarcinoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2013-11-04
Completion: 2026-11-30
Conditions
Pancreatic Ductal Adenocarcinoma
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT01787409 | ACTIVE_NOT_RECRUITING | NA
565 Participants

Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2013-03-06
Completion: 2028-06-30
Conditions
Aggressive Non-Hodgkin Lymphoma Anaplastic Large Cell Lymphoma Angioimmunoblastic T-Cell Lymphoma Chronic Lymphocytic Leukemia Diffuse Large B-Cell Lymphoma Enteropathy-Associated T-Cell Lymphoma Hepatosplenic T-Cell Lymphoma Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma Mediastinal (Thymic) Large B-Cell Lymphoma Nasal Type Extranodal NK/T-Cell Lymphoma Peripheral T-Cell Lymphoma, Not Otherwise Specified Primary Cutaneous Anaplastic Large Cell Lymphoma Refractory Anaplastic Large Cell Lymphoma Small Lymphocytic Lymphoma Subcutaneous Panniculitis-Like T-Cell Lymphoma
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT01733082 | RECRUITING
500 Participants

The Mycophenolate Pregnancy Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2012-11-20
Completion: 2026-10-31
Conditions
Heart Transplantation, Kidney Transplantation, Liver Transplantation, Autoimmune Diseases
No Results Yet
NCT00565851 | ACTIVE_NOT_RECRUITING | PHASE3
1052 Participants

Carboplatin, Paclitaxel and Gemcitabine Hydrochloride With or Without Bevacizumab After Surgery in Treating Patients With Recurrent Ovarian, Epithelial, Primary Peritoneal, or Fallopian Tube Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2007-12-06
Completion: 2019-04-30
Conditions
Clear Cell Adenocarcinoma Fallopian Tube Clear Cell Adenocarcinoma Fallopian Tube Endometrioid Adenocarcinoma Fallopian Tube Mucinous Adenocarcinoma Fallopian Tube Serous Adenocarcinoma Fallopian Tube Transitional Cell Carcinoma Fallopian Tube Undifferentiated Carcinoma Mucinous Adenocarcinoma Ovarian Brenner Tumor Ovarian Clear Cell Adenocarcinofibroma Ovarian Clear Cell Adenocarcinoma Ovarian Endometrioid Adenocarcinoma Ovarian Seromucinous Carcinoma Ovarian Serous Adenocarcinoma Ovarian Transitional Cell Carcinoma Ovarian Undifferentiated Carcinoma Primary Peritoneal Clear Cell Adenocarcinoma Primary Peritoneal Endometrioid Adenocarcinoma Primary Peritoneal Serous Adenocarcinoma Primary Peritoneal Transitional Cell Carcinoma Primary Peritoneal Undifferentiated Carcinoma Recurrent Fallopian Tube Carcinoma Recurrent Ovarian Carcinoma Recurrent Primary Peritoneal Carcinoma Undifferentiated Carcinoma
Interventions
BIOLOGICAL DRUG OTHER
Results Available
NCT00515060 | RECRUITING
450 Participants

Psychophysical Studies of Cancer Therapy Pain

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2001-01-23
Completion: 2028-04-30
Conditions
Advanced Cancer Pain
Interventions
OTHER
No Results Yet
NCT00465712 | TERMINATED | NA
119 Participants

Effect of Amnioinfusion on External Cephalic Version Successful Rate

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2006-07-31
Completion: 2011-05-31
Conditions
Breech Presentation
Interventions
PROCEDURE
No Results Yet
NCT00255346 | COMPLETED | PHASE2
68 Participants

Dasatinib as Therapy for Myeloproliferative Disorders (MPDs)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2005-11-15
Completion: 2017-03-03
Conditions
Acute Myeloid Leukemia Myelodysplastic Syndromes Agnogenic Myeloid Metaplasia Myelofibrosis Hypereosinophilic Syndrome Polycythemia Vera Mastocytosis Leukemia, Myelomonocytic, Chronic
Interventions
DRUG
Results Available
NCT00177268 | RECRUITING
200 Participants

Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2004-10-31
Completion: 2030-01-31
Conditions
Cutaneous T-cell Lymphoma Sezary Syndrome Mycosis Fungoides Eczema Atopic Dermatitis
Interventions
OTHER
No Results Yet
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