Clinical Trials

Showing trials with last updates posted in 2025.

NCT06549699 | COMPLETED | NA
206 Participants

Medically Used Tailored Traditional Food to Optimize Nutrition in Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-05-12
Completion: 2025-11-11
Conditions
Heart Failure
Interventions
OTHER
No Results Yet
NCT06542874 | COMPLETED | PHASE2
448 Participants

A Research Study Comparing How Well Different Doses of the Medicine NNC0487-0111 Lower Blood Sugar in People With Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-08-07
Completion: 2025-10-01
Conditions
Type 2 Diabetes (T2D)
Interventions
DRUG
No Results Yet
NCT06535659 | RECRUITING
122 Participants

VitaFlow LIBERTY Europe

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2025-05-06
Completion: 2027-06-06
Conditions
Aortic Valve Stenosis
Interventions
DEVICE
No Results Yet
NCT06534723 | RECRUITING | PHASE3
570 Participants

Phase 3 Clinical Trial of Wujia Yizhi Granules in the Treatment of Mild-to-moderate Alzheimer's Dementia (Syndrome of Deficiency of Spleen and Kidney)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-08-20
Completion: 2026-08-31
Conditions
Alzheimer's Dementia
Interventions
DRUG
No Results Yet
NCT06526546 | ACTIVE_NOT_RECRUITING
356 Participants

ADVENT Trial Long Term Outcomes Evaluating Atrial Fibrillation Progression Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-10-31
Completion: 2026-02-28
Conditions
Paroxysmal Atrial Fibrillation
No Results Yet
NCT06525532 | RECRUITING
35 Participants

Clinical-MRI Evaluation in Patients Undergoing Subtalar Arthrorisis With Reabsorbable Endorthesis Implant in PLLA

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-06-12
Completion: 2026-11-30
Conditions
Lower Limb Deformity
Interventions
OTHER
No Results Yet
NCT06522932 | RECRUITING | PHASE1
32 Participants

PET Imaging Study of 64Cu-GRIP B for Patients Receiving CD19-directed CAR-T Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-10-23
Completion: 2027-01-31
Conditions
Non Hodgkin Lymphoma
Interventions
DRUG PROCEDURE
No Results Yet
NCT06516874 | RECRUITING | NA
13 Participants

A Pilot Study of Trauma-Focused Cognitive-Behavioral Therapy for Treatment of Post-traumatic Stress in Adults.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-10-22
Completion: 2026-02-28
Conditions
Post Traumatic Stress Disorder Complex Post-Traumatic Stress Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT06510998 | RECRUITING | NA
390 Participants

Isometric Resistance Exercise for Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-01-01
Completion: 2027-07-28
Conditions
Hypertension
Interventions
BEHAVIORAL
No Results Yet
NCT06494189 | COMPLETED | PHASE1
9 Participants

Low-dose Radiotherapy Plus Tislelizumab in Combination With Afatinib for Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-07-31
Completion: 2025-04-10
Conditions
Head and Neck Cancer
Interventions
BIOLOGICAL DRUG RADIATION
No Results Yet
NCT06492434 | COMPLETED | NA
16 Participants

Enhancing Community Participation Through Peer-Delivered Decision Support

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-07-01
Completion: 2025-08-31
Conditions
Severe Mental Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT06475989 | RECRUITING | PHASE3
264 Participants

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-08-22
Completion: 2030-09-30
Conditions
Refractory Differentiated Thyroid Gland Carcinoma
Interventions
PROCEDURE DRUG OTHER
No Results Yet
NCT06475235 | RECRUITING | PHASE1
15 Participants

Pembrolizumab + Chemotherapy in Newly Diagnosed PCNSL

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-10-18
Completion: 2025-12-30
Conditions
Lymphoma Primary Central Nervous System Lymphoma
Interventions
DRUG
No Results Yet
NCT06470815 | ENROLLING_BY_INVITATION
400 Participants

ROADSTER 3 Extended Follow-up Sub-Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-07-31
Completion: 2029-07-31
Conditions
Carotid Artery Diseases
Interventions
PROCEDURE
No Results Yet
NCT06446661 | NOT_YET_RECRUITING | NA
38 Participants

Using Text Messages to Improve Oral Chemotherapy for Adolescents and Adults With Acute Lymphoblastic Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-12-15
Completion: 2027-06-15
Conditions
Acute Lymphoblastic Leukemia
Interventions
OTHER
No Results Yet
NCT06431815 | ACTIVE_NOT_RECRUITING
228 Participants

ADVENT Post Approval Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-09-25
Completion: 2028-10-31
Conditions
Paroxysmal Atrial Fibrillation
Interventions
DEVICE
No Results Yet
NCT06425549 | RECRUITING | PHASE3
168 Participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Ustekinumab in Children and Adolescents From 6 Years to Less Than 18 Years of Age With Moderate to Severe Plaque Psoriasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-06-25
Completion: 2028-08-21
Conditions
Moderate to Severe Plaque Psoriasis
Interventions
DRUG
No Results Yet
NCT06414967 | RECRUITING | NA
15 Participants

Study to Evaluate Music Therapy on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-10-15
Completion: 2026-07-31
Conditions
Huntington Disease
Interventions
OTHER
No Results Yet
NCT06400706 | COMPLETED | NA
92 Participants

Effect of Electroencephalography Guided General Anesthesia on Postoperative Delirium in Children

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-05-15
Completion: 2024-12-15
Conditions
Postoperative Delirium Postoperative Pain
Interventions
PROCEDURE
No Results Yet
NCT06380660 | RECRUITING | PHASE1/PHASE2
298 Participants

Study of ACE-86225106 to Treat Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-03-22
Completion: 2028-12-21
Conditions
Solid Tumor, Adult BRCA1 Mutation BRCA2 Mutation Ovarian Cancer Breast Cancer Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06378528 | SUSPENDED | EARLY_PHASE1
5 Participants

Ketamine-assisted Psychotherapy for Adolescent PTSD (KAP)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-03-31
Completion: 2027-03-31
Conditions
Posttraumatic Stress Disorder
Interventions
DRUG DEVICE
No Results Yet
NCT06373159 | ACTIVE_NOT_RECRUITING
5740 Participants

An Observational Study to Learn About the Occurrence of Disseminated Intravascular Coagulation Among Adults With Sepsis in Japan

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-03-22
Completion: 2025-12-31
Conditions
Sepsis Disseminated Intravascular Coagulation
Interventions
OTHER
No Results Yet
NCT06367465 | RECRUITING
50 Participants

Feasibility and Acceptability of HCV Treatment in Pregnancy

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-02-01
Completion: 2026-02-28
Conditions
Hepatitis C Pregnancy Complications
Interventions
DRUG
No Results Yet
NCT06350890 | COMPLETED | PHASE3
408 Participants

Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-11-05
Completion: 2024-12-12
Conditions
T2DM (Type 2 Diabetes Mellitus)
Interventions
DRUG
No Results Yet
NCT06343870 | RECRUITING | PHASE3
140 Participants

Estradiol and Testosterone Subdermal Implants for Menopause Treatment (ESTIME)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-12-18
Completion: 2026-08-18
Conditions
Menopause Testosterone Deficiency Estrogen Deficiency
Interventions
DRUG
No Results Yet
NCT06342375 | RECRUITING | NA
425000 Participants

Enrollment Barriers, Procedural Denials, and Loss of Medicaid Coverage

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-02-12
Completion: 2026-09-30
Conditions
No Medicaid Coverage
Interventions
OTHER
No Results Yet
NCT06340360 | ACTIVE_NOT_RECRUITING | PHASE2
94 Participants

A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Severe to Very Severe Alopecia Areata in Adult Patients (Rezolve AA)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-04-02
Completion: 2025-11-26
Conditions
Alopecia Areata
Interventions
DRUG
No Results Yet
NCT06335524 | RECRUITING | NA
188 Participants

Infant-Maternal Partnership and Cognitive Training Study for Preterm Infants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-11-01
Completion: 2026-12-31
Conditions
Child Development Infant Development Infant, Premature, Diseases
Interventions
BEHAVIORAL
No Results Yet
NCT06334016 | NOT_YET_RECRUITING | EARLY_PHASE1
60 Participants

Evaluating the Delivery and Effects of THC Vaping Liquids in the Bloodstream

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-02-15
Completion: 2028-03-01
Conditions
Cannabis Dependence
Interventions
PROCEDURE DRUG OTHER
No Results Yet
NCT06320405 | RECRUITING | PHASE1/PHASE2
38 Participants

Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-05-21
Completion: 2027-04-01
Conditions
Advanced Malignant Solid Neoplasm Metastatic Malignant Solid Neoplasm Recurrent Malignant Solid Neoplasm Refractory Malignant Solid Neoplasm
Interventions
BIOLOGICAL PROCEDURE DRUG
No Results Yet
NCT06305949 | RECRUITING | NA
30 Participants

Clinical Trial on the Safety and Efficacy of Optimized Transcranial Direct Current Stimulation for the Swallowing Function in Patients With Post-Stroke Dysphagia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-04-22
Completion: 2026-02-28
Conditions
Deglutition Disorders
Interventions
DEVICE
No Results Yet
NCT06291285 | COMPLETED | PHASE1
44 Participants

A Study to Test How Either a Capsule or a Tablet With NDec (Decitabine and Tetrahydrouridine) Works in the Body of Healthy People

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-02-27
Completion: 2024-06-10
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT06285760 | RECRUITING
64 Participants

Effect of Acetazolamide on Diuresis and Natriuresis in Patients With Acute Heart Failure (SANDI STUDY)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-03-01
Completion: 2026-05-31
Conditions
Heart Failure Persistent Congestion
Interventions
DRUG
No Results Yet
NCT06271265 | RECRUITING | PHASE1
48 Participants

Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-03-29
Completion: 2027-01-31
Conditions
Postoperative Pain
Interventions
DRUG
No Results Yet
NCT06257264 | RECRUITING | PHASE1
258 Participants

A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-03-11
Completion: 2028-04-30
Conditions
Breast Cancer Small Cell Lung Cancer Ovarian Cancer Gastric Cancer Hormone-receptor-positive Breast Cancer Hormone Receptor Positive HER-2 Negative Breast Cancer Advanced Solid Tumor Endometrial Cancer Prostate Cancer TNBC - Triple-Negative Breast Cancer GastroEsophageal Cancer Bladder Cancer
Interventions
DRUG
No Results Yet
NCT06251986 | COMPLETED
310 Participants

A Cross-sectional Study to Assess the Effectiveness and Safety of Ofatumumab (Kesimpta®) in Patients With Relapsing Multiple Sclerosis in the Spanish Clinical Practice

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-02-26
Completion: 2024-12-23
Conditions
Relapsing Forms of Multiple Sclerosis
Interventions
OTHER
No Results Yet
NCT06249178 | RECRUITING
1000 Participants

EV Based Platform for Monitoring Therapeutics Response During Pregnancy (ARISE)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-07-02
Completion: 2028-09-01
Conditions
Preeclampsia
No Results Yet
NCT06221839 | NOT_YET_RECRUITING
72 Participants

Structural Racism, Reward Related Decision Making and Substance Use Risk

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2026-01-31
Completion: 2026-07-31
Conditions
Structural Racism Substance Use Risk
No Results Yet
NCT06193863 | RECRUITING
50 Participants

An Observational Study to Learn More About How Safe Rivaroxaban is And How Well it Works in Children With Congenital Heart Disease Who Had a Heart Surgery Called the Fontan Procedure

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-06-18
Completion: 2026-06-30
Conditions
Prevention of Venous Thromboembolism Congenital Heart Disease Fontan Procedure Children
Interventions
DRUG
No Results Yet
NCT06193057 | RECRUITING | NA
24 Participants

Comparison of Customized and Standard Total Ankle Prostheses

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-07-26
Completion: 2026-04-30
Conditions
Ankle Osteoarthritis
Interventions
PROCEDURE
No Results Yet
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