Clinical Trials
Showing trials with last updates posted in 2025.
168
Participants
A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Ustekinumab in Children and Adolescents From 6 Years to Less Than 18 Years of Age With Moderate to Severe Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-06-25
Completion:
2028-08-21
Conditions
Moderate to Severe Plaque Psoriasis
Interventions
DRUG
No Results Yet
15
Participants
Study to Evaluate Music Therapy on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-10-15
Completion:
2026-07-31
Conditions
Huntington Disease
Interventions
OTHER
No Results Yet
92
Participants
Effect of Electroencephalography Guided General Anesthesia on Postoperative Delirium in Children
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-05-15
Completion:
2024-12-15
Conditions
Postoperative Delirium
Postoperative Pain
Interventions
PROCEDURE
No Results Yet
298
Participants
Study of ACE-86225106 to Treat Patients With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-03-22
Completion:
2028-12-21
Conditions
Solid Tumor, Adult
BRCA1 Mutation
BRCA2 Mutation
Ovarian Cancer
Breast Cancer
Prostate Cancer
Interventions
DRUG
No Results Yet
5
Participants
Ketamine-assisted Psychotherapy for Adolescent PTSD (KAP)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2026-03-31
Completion:
2027-03-31
Conditions
Posttraumatic Stress Disorder
Interventions
DRUG
DEVICE
No Results Yet
5740
Participants
An Observational Study to Learn About the Occurrence of Disseminated Intravascular Coagulation Among Adults With Sepsis in Japan
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2024-03-22
Completion:
2025-12-31
Conditions
Sepsis
Disseminated Intravascular Coagulation
Interventions
OTHER
No Results Yet
50
Participants
Feasibility and Acceptability of HCV Treatment in Pregnancy
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2024-02-01
Completion:
2026-02-28
Conditions
Hepatitis C
Pregnancy Complications
Interventions
DRUG
No Results Yet
408
Participants
Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2023-11-05
Completion:
2024-12-12
Conditions
T2DM (Type 2 Diabetes Mellitus)
Interventions
DRUG
No Results Yet
140
Participants
Estradiol and Testosterone Subdermal Implants for Menopause Treatment (ESTIME)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-12-18
Completion:
2026-08-18
Conditions
Menopause
Testosterone Deficiency
Estrogen Deficiency
Interventions
DRUG
No Results Yet
425000
Participants
Enrollment Barriers, Procedural Denials, and Loss of Medicaid Coverage
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-02-12
Completion:
2026-09-30
Conditions
No Medicaid Coverage
Interventions
OTHER
No Results Yet
94
Participants
A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Severe to Very Severe Alopecia Areata in Adult Patients (Rezolve AA)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-04-02
Completion:
2025-11-26
Conditions
Alopecia Areata
Interventions
DRUG
No Results Yet
188
Participants
Infant-Maternal Partnership and Cognitive Training Study for Preterm Infants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-11-01
Completion:
2026-12-31
Conditions
Child Development
Infant Development
Infant, Premature, Diseases
Interventions
BEHAVIORAL
No Results Yet
60
Participants
Evaluating the Delivery and Effects of THC Vaping Liquids in the Bloodstream
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2026-02-15
Completion:
2028-03-01
Conditions
Cannabis Dependence
Interventions
PROCEDURE
DRUG
OTHER
No Results Yet
38
Participants
Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-05-21
Completion:
2027-04-01
Conditions
Advanced Malignant Solid Neoplasm
Metastatic Malignant Solid Neoplasm
Recurrent Malignant Solid Neoplasm
Refractory Malignant Solid Neoplasm
Interventions
BIOLOGICAL
PROCEDURE
DRUG
No Results Yet
30
Participants
Clinical Trial on the Safety and Efficacy of Optimized Transcranial Direct Current Stimulation for the Swallowing Function in Patients With Post-Stroke Dysphagia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-04-22
Completion:
2026-02-28
Conditions
Deglutition Disorders
Interventions
DEVICE
No Results Yet
44
Participants
A Study to Test How Either a Capsule or a Tablet With NDec (Decitabine and Tetrahydrouridine) Works in the Body of Healthy People
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-02-27
Completion:
2024-06-10
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
64
Participants
Effect of Acetazolamide on Diuresis and Natriuresis in Patients With Acute Heart Failure (SANDI STUDY)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2024-03-01
Completion:
2026-05-31
Conditions
Heart Failure
Persistent Congestion
Interventions
DRUG
No Results Yet
48
Participants
Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-03-29
Completion:
2027-01-31
Conditions
Postoperative Pain
Interventions
DRUG
No Results Yet
258
Participants
A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-03-11
Completion:
2028-04-30
Conditions
Breast Cancer
Small Cell Lung Cancer
Ovarian Cancer
Gastric Cancer
Hormone-receptor-positive Breast Cancer
Hormone Receptor Positive HER-2 Negative Breast Cancer
Advanced Solid Tumor
Endometrial Cancer
Prostate Cancer
TNBC - Triple-Negative Breast Cancer
GastroEsophageal Cancer
Bladder Cancer
Interventions
DRUG
No Results Yet
310
Participants
A Cross-sectional Study to Assess the Effectiveness and Safety of Ofatumumab (Kesimpta®) in Patients With Relapsing Multiple Sclerosis in the Spanish Clinical Practice
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2024-02-26
Completion:
2024-12-23
Conditions
Relapsing Forms of Multiple Sclerosis
Interventions
OTHER
No Results Yet
1000
Participants
EV Based Platform for Monitoring Therapeutics Response During Pregnancy (ARISE)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2024-07-02
Completion:
2028-09-01
Conditions
Preeclampsia
No Results Yet
72
Participants
Structural Racism, Reward Related Decision Making and Substance Use Risk
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2026-01-31
Completion:
2026-07-31
Conditions
Structural Racism
Substance Use Risk
No Results Yet
50
Participants
An Observational Study to Learn More About How Safe Rivaroxaban is And How Well it Works in Children With Congenital Heart Disease Who Had a Heart Surgery Called the Fontan Procedure
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2024-06-18
Completion:
2026-06-30
Conditions
Prevention of Venous Thromboembolism
Congenital Heart Disease
Fontan Procedure
Children
Interventions
DRUG
No Results Yet
24
Participants
Comparison of Customized and Standard Total Ankle Prostheses
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2023-07-26
Completion:
2026-04-30
Conditions
Ankle Osteoarthritis
Interventions
PROCEDURE
No Results Yet
19
Participants
Safety and Effectiveness of A Novel Enteral Feeding System: Prospective Study.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2023-11-14
Completion:
2024-11-06
Conditions
Enteral Feeding
Interventions
DEVICE
150
Participants
Delayed Cold-Stored Platelets -PLTS-1
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-06-05
Completion:
2026-06-30
Conditions
Platelets
Bleeding
Cardiopulmonary Bypass
Cardiac Surgery
Interventions
BIOLOGICAL
No Results Yet
1200
Participants
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2023-12-13
Completion:
2032-09-07
Conditions
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Interventions
DRUG
No Results Yet
50
Participants
Risk-Based Selection of Treatment Modalities for Odontogenic Keratocysts: A 10-Year Randomized Clinical Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2023-02-24
Completion:
2024-06-30
Conditions
Odontogenic Cysts
Interventions
PROCEDURE
No Results Yet
300
Participants
BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2023-12-01
Completion:
2028-06-30
Conditions
Advanced Solid Tumor
Advanced Breast Cancer
Metastatic Breast Cancer
Hormone-receptor-positive Breast Cancer
Hormone Receptor Positive Breast Carcinoma
Hormone Receptor Positive Malignant Neoplasm of Breast
HER2-negative Breast Cancer
Hormone Receptor Positive HER-2 Negative Breast Cancer
Non-small Cell Lung Cancer
Interventions
DRUG
No Results Yet
12
Participants
A Safety Assessment of Oral Letermovir in Infants With Symptomatic Congenital Cytomegalovirus
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-02-19
Completion:
2026-05-15
Conditions
Congenital Cytomegalovirus Infection
Interventions
DRUG
No Results Yet
40
Participants
A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-07-08
Completion:
2026-09-30
Conditions
Juvenile Psoriatic Arthritis
Interventions
DRUG
No Results Yet
100
Participants
The Sequestration of Holistic Stress Management Techniques for Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2026-06-26
Completion:
2028-12-31
Conditions
Stress, Job
PTSD
Hypervigilance
Hyperthyroidism
Migraine
Migraine With Aura
Immunodeficiency
Sickle Cell Trait
Sickle Cell Disease
Anemia, Sickle Cell
Anemia
Fatigue
Anxiety
Depression
Flat Feet
Lordosis
TBI (Traumatic Brain Injury)
Rheumatoid Arthritis
Arthritis
Masturbation
Priapism
Erectile Dysfunction
Flight Reaction
Hypertension
Sexual Arousal Disorder
Hemorrhoids
Fibroid
Interventions
BEHAVIORAL
No Results Yet
65
Participants
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-06-12
Completion:
2027-07-09
Conditions
Ulcerative Colitis
Interventions
DRUG
No Results Yet
444
Participants
Effect of FPCA on Incidence of Emergency Delirium in Children After Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2023-10-24
Completion:
2026-09-30
Conditions
Postoperative Complications
Child
Family
Emergence Delirium
General Anaesthesia
Perioperative Care
Interventions
OTHER
No Results Yet
97
Participants
PET/MR for Characterization of Renal Masses (RMs)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2023-08-01
Completion:
2028-06-01
Conditions
Renal Tumor
Renal Cell Carcinoma
Renal Tumor, Benign
Interventions
DIAGNOSTIC_TEST
No Results Yet
100
Participants
A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-04-18
Completion:
2027-06-28
Conditions
Crohn's Disease
Interventions
DRUG
No Results Yet
471
Participants
Phase 3b Study to Assess the Efficacy, Safety, and Tolerability of Remibrutinib in Comparison to Placebo, With Omalizumab as Active Control, in Adult CSU Patients, Followed by an Open-label 52-week Optional Extension.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2023-11-15
Completion:
2025-09-17
Conditions
Chronic Spontaneous Urticaria
Interventions
DRUG
No Results Yet
325
Participants
Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2023-10-16
Completion:
2026-12-31
Conditions
Stress
Anxiety
Interventions
BEHAVIORAL
No Results Yet
30
Participants
An Exercise Intervention to Improve Overall Brain Health
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-01-23
Completion:
2026-01-12
Conditions
Brain Care Score
Exercise
Hypertension
BMI
Interventions
BEHAVIORAL
No Results Yet
150
Participants
Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2023-09-18
Completion:
2027-01-31
Conditions
Myopia
Juvenile Myopia
Myopia Progression
Interventions
DEVICE
No Results Yet
Showing 40 trials per page