An Exercise Intervention to Improve Overall Brain Health
NCT ID: NCT06035094
Last Updated: 2025-12-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
NA
30 participants
INTERVENTIONAL
2024-01-23
2026-01-12
Brief Summary
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* To test the effect of moderate vs intensive exercise on Brain Care Score outcomes.
* To ascertain the differential impact of moderate vs high intensity exercise in reducing hypertension and its downstream effects.
Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
SINGLE
Study Groups
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High Intensity Interval Training (HIIT) exercise group,
Participants will be asked to exercise independently 4 days/week for 10 weeks, following a high intensity interval training (HIIT) protocol.
Exercise Intervention to improve overall Brain Health
During each exercise session, the participant will be assigned to the HIIT or MIT exercise group and asked to ride the stationary bicycle for approximately 30-40 minutes, while wearing the heart rate monitor and recording the session on their smart phone application. For each exercise session, the Polar Beat application will record the time in each of four intensity "zones". The participant will receive training on how to use the outlined schedule during the initial supervised training session.
Moderate Intensity Training (MIT) exercise group
Participants will be asked to exercise independently 4 days/week for 10 weeks, following a moderate intensity training (MIT) protocol.
Exercise Intervention to improve overall Brain Health
During each exercise session, the participant will be assigned to the HIIT or MIT exercise group and asked to ride the stationary bicycle for approximately 30-40 minutes, while wearing the heart rate monitor and recording the session on their smart phone application. For each exercise session, the Polar Beat application will record the time in each of four intensity "zones". The participant will receive training on how to use the outlined schedule during the initial supervised training session.
Control exercise group
Participants will be advised to follow the American Heart Association (AHA) guidelines on exercise.
Exercise Intervention to improve overall Brain Health
During each exercise session, the participant will be assigned to the HIIT or MIT exercise group and asked to ride the stationary bicycle for approximately 30-40 minutes, while wearing the heart rate monitor and recording the session on their smart phone application. For each exercise session, the Polar Beat application will record the time in each of four intensity "zones". The participant will receive training on how to use the outlined schedule during the initial supervised training session.
Interventions
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Exercise Intervention to improve overall Brain Health
During each exercise session, the participant will be assigned to the HIIT or MIT exercise group and asked to ride the stationary bicycle for approximately 30-40 minutes, while wearing the heart rate monitor and recording the session on their smart phone application. For each exercise session, the Polar Beat application will record the time in each of four intensity "zones". The participant will receive training on how to use the outlined schedule during the initial supervised training session.
Eligibility Criteria
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Inclusion Criteria
* have a body mass index ≥ 25 kg/m2
* are between the ages of 35-65 years old
* access to a smart phone that allows installation of 2 two applications that record your workouts
* pass a fitness evaluation.
Exclusion Criteria
* weight over 300 lbs
* unable to pass the fitness evaluation
* BMI less than 25kg/m2
35 Years
65 Years
ALL
Yes
Sponsors
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University of Alabama at Birmingham
OTHER
Responsible Party
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Pamela G Bowen PhD, CRNP, FNP-BC, BBA
Associate Professor
Principal Investigators
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Pamela G. Bowen, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Alabama at Birmingham
Locations
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UAB
Birmingham, Alabama, United States
Countries
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Other Identifiers
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2027708
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
IRB-300011511
Identifier Type: -
Identifier Source: org_study_id