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Clinical Trials

Showing trials with last updates posted in 2025.

NCT04166318 | ACTIVE_NOT_RECRUITING | PHASE2
252 Participants

Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-01-02
Completion: 2029-12-31
Conditions
Anal Basaloid Carcinoma Anal Canal Cloacogenic Carcinoma Anal Canal Squamous Cell Carcinoma Anal Margin Squamous Cell Carcinoma Stage I Anal Cancer AJCC v8 Stage IIA Anal Cancer AJCC v8
Interventions
PROCEDURE DRUG OTHER RADIATION
No Results Yet
NCT04157101 | COMPLETED | NA
260 Participants

Health Coaching for Chronic Multisymptom Illness

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-04-30
Completion: 2025-05-01
Conditions
Pain Predominant Chronic Multisymptom Illness
Interventions
BEHAVIORAL
No Results Yet
NCT04115631 | ACTIVE_NOT_RECRUITING | PHASE2
360 Participants

A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-12-13
Completion: 2026-12-31
Conditions
Liver Lymphoma Mantle Cell Lymphoma
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT04045496 | COMPLETED | PHASE1
40 Participants

A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-09-26
Completion: 2022-12-16
Conditions
Non-small Cell Lung Cancer Colorectal Cancer Pancreatic Ductal Carcinoma Esophageal Squamous Cell Carcinoma Head and Neck Squamous Cell Carcinoma Breast Cancer Other Solid Tumors
Interventions
DRUG
No Results Yet
NCT04031040 | ACTIVE_NOT_RECRUITING | NA
110 Participants

A Post-market Clinical Follow up of the Genio® System for the Treatment of Obstructive Sleep Apnea in Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-09-01
Completion: 2026-10-30
Conditions
Obstructive Sleep Apnea
Interventions
DEVICE
No Results Yet
NCT03992651 | COMPLETED | NA
20 Participants

Optical Transcutaneous Sensors of Capnia and Oxygenation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-06-12
Completion: 2019-06-13
Conditions
Blood Gas Monitoring, Transcutaneous
Interventions
DEVICE
No Results Yet
NCT03875755 | ACTIVE_NOT_RECRUITING | NA
1080 Participants

Myo-inositol for Reduction of Insulin Therapy in Gestational Diabetes Mellitus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-03-04
Completion: 2026-09-20
Conditions
Gestational Diabetes Mellitus
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT03869216 | COMPLETED | NA
161 Participants

Fostering Shared Decision-making About Prostate Cancer Screening Among Clinicians and African American Men

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-08-17
Completion: 2023-11-30
Conditions
Prostate Cancer
Interventions
BEHAVIORAL
Results Available
NCT03857191 | COMPLETED
396 Participants

Nutritional Rehabilitation and Sleep Apnea in the Obese

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2019-03-22
Completion: 2022-04-11
Conditions
Obese Sleep Apnea, Obstructive
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT03780062 | COMPLETED | PHASE3
720 Participants

Interest of S100B Protein for Patient Victim of Minor Traumatic Brain Injury and Treated by Antiplatelet

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-01-25
Completion: 2025-04-28
Conditions
Minor Traumatic Brain Injury Treatment by Antiplatelet
Interventions
BIOLOGICAL
No Results Yet
NCT03760731 | COMPLETED | NA
74 Participants

Thriving in the Midst of Moral Pain: The Acceptability and Feasibility of Acceptance and Commitment Therapy for Moral Injury (ACT-MI) Among Warzone Veterans

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-04-01
Completion: 2024-10-31
Conditions
Moral Injury
Interventions
BEHAVIORAL
Results Available
NCT03734731 | NOT_YET_RECRUITING | NA
1000 Participants

Cannabis Vs Opioids Pain Management Objective Testing Comparisons

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-06-03
Completion: 2027-02-03
Conditions
Chronic Pain Circulatory Disorders
Interventions
DEVICE DRUG
No Results Yet
NCT03729180 | RECRUITING | NA
1900 Participants

The ImPreSS Trial: Pharmacogenomic Decision Making at Time of Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-01-22
Completion: 2027-08-22
Conditions
Surgery
Interventions
PROCEDURE DIAGNOSTIC_TEST OTHER
No Results Yet
NCT03712592 | COMPLETED | NA
83 Participants

Physiological Constraints Associated With Trail Running

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2018-07-23
Completion: 2018-08-23
Conditions
Muscle Fatigue
Interventions
OTHER
No Results Yet
NCT03697148 | ACTIVE_NOT_RECRUITING | NA
852 Participants

Multiparametric MRI in Evaluating Cancer Stage and Helping Treatment Planning in Patients With Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-02-11
Completion: 2026-08-31
Conditions
Prostate Carcinoma
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT03643991 | COMPLETED | NA
30 Participants

Decreasing Agitation in Patients With Dementia Through the Use of Weighted Blankets

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2018-04-11
Completion: 2025-10-28
Conditions
Dementia
Interventions
OTHER
No Results Yet
NCT03630614 | ACTIVE_NOT_RECRUITING | PHASE3
650 Participants

Randomized Trial of Electronic Cigarettes With or Without Nicotine in Smoking Cessation.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2018-10-17
Completion: 2029-02-28
Conditions
Smoking Cessation Smoking, Cigarette Electronic Cigarette
Interventions
DRUG
No Results Yet
NCT03502668 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
160 Participants

Phase 1-2 Study of Low Dose ASTX727 (ASTX727 LD) in Lower Risk MDS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2018-07-27
Completion: 2025-12-31
Conditions
Myelodysplastic Syndromes
Interventions
DRUG
No Results Yet
NCT03493425 | RECRUITING | PHASE2
82 Participants

Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-03-12
Completion: 2029-03-31
Conditions
Stage III Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v6 and v7 Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7
Interventions
DRUG RADIATION OTHER PROCEDURE
No Results Yet
NCT03483233 | COMPLETED | NA
51 Participants

Neural Bases of the Check Process

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2018-11-23
Completion: 2020-01-16
Conditions
Healthy Volunteers
Interventions
OTHER
No Results Yet
NCT03479723 | COMPLETED
1793 Participants

Identification of Predictors for Coronary Plaque Erosion in Patients With Acute Coronary Syndrome

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2017-12-01
Completion: 2019-12-01
Conditions
Acute Coronary Syndrome
No Results Yet
NCT03457935 | ACTIVE_NOT_RECRUITING
450 Participants

Detection of Early Idiopathic Pulmonary Fibrosis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2018-04-10
Completion: 2025-12-31
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
OTHER
No Results Yet
NCT03451981 | COMPLETED | NA
47 Participants

Non Surgical Protocol for Treatment of Peri-implantitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2018-12-02
Completion: 2021-10-06
Conditions
Peri-Implantitis
Interventions
PROCEDURE
No Results Yet
NCT03445962 | COMPLETED
40 Participants

19/5000 (SYNAPSOT21) Predictive Factors of Sleep Apnea Syndrome in Down Syndrome

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2017-11-15
Completion: 2019-07-11
Conditions
Down Syndrome Sleep Apnea, Obstructive Polysomnography
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT03428646 | ACTIVE_NOT_RECRUITING
858 Participants

Study of Patients Receiving DUPIXENT® for Atopic Dermatitis (AD)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2018-04-06
Completion: 2027-03-30
Conditions
Dermatitis, Atopic
Interventions
DRUG
No Results Yet
NCT03326310 | RECRUITING | PHASE1
18 Participants

Selumetinib and Azacitidine in High Risk Chronic Blood Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2018-09-04
Completion: 2027-09-04
Conditions
Chronic Myeloid Leukemia Myelofibroses
Interventions
DRUG
No Results Yet
NCT03273023 | COMPLETED
2059 Participants

PROMUS PREMIER™ China Post-Approval Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2018-01-11
Completion: 2020-12-28
Conditions
Coronary Artery Disease
Interventions
DEVICE
No Results Yet
NCT03267433 | ACTIVE_NOT_RECRUITING | PHASE3
689 Participants

Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2017-11-27
Completion: 2027-01-31
Conditions
Mantle Cell Lymphoma
Interventions
PROCEDURE BIOLOGICAL
No Results Yet
NCT03233191 | ACTIVE_NOT_RECRUITING | PHASE3
108508 Participants

Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2017-09-28
Completion: 2028-12-31
Conditions
Breast Screening
Interventions
PROCEDURE OTHER
No Results Yet
NCT03020251 | ACTIVE_NOT_RECRUITING | NA
90 Participants

Effects of Preoperative Rehabilitation in Patients Resected for Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2017-05-12
Completion: 2025-10-31
Conditions
Lungcancer
Interventions
OTHER
No Results Yet
NCT02994121 | RECRUITING
7500 Participants

Prospective Investigation of Multiple Sclerosis in the Three Rivers Region

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2016-12-31
Completion: 2047-01-31
Conditions
Multiple Sclerosis
No Results Yet
NCT02972801 | RECRUITING | NA
1500 Participants

Testicular Tissue Cryopreservation for Fertility Preservation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2010-01-06
Completion: 2030-01-01
Conditions
Cancer Autoimmune Disorders
Interventions
PROCEDURE
No Results Yet
NCT02926690 | RECRUITING | PHASE1
70 Participants

Safety Study of MELK Inhibitor to Treat Patients With Advanced Breast Cancer and Triple Negative Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2017-05-29
Completion: 2027-09-30
Conditions
Relapsed/Refractory Locally Advanced or Metastatic Breast Cancer and Triple Negative Breast Cancer
Interventions
DRUG
No Results Yet
NCT02850367 | COMPLETED | NA
63 Participants

Effect of NO Precursors on Physiological Responses to Exercise

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2016-05-09
Completion: 2021-09-30
Conditions
Physiology
Interventions
DIETARY_SUPPLEMENT BIOLOGICAL
No Results Yet
NCT02806258 | TERMINATED | PHASE1/PHASE2
362 Participants

Comparing Sequential Neoadjuvant Treatment Including Chemotherapy and Accelerated Radiation Focused to the Tumor Bed vs Neoadjuvant Chemotherapy Alone

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2016-04-26
Completion: 2024-05-16
Conditions
Radiation Therapy, Breast Cancer, Sequential Partial Breast Irradiation Intermediate and High-risk Luminal and Triple Negative Breast Cancer
Interventions
RADIATION DRUG
No Results Yet
NCT02796534 | COMPLETED
825 Participants

Prevalence of Obstructive Sleep Apnea Syndrome in Type 1 Diabetic Patients Treated With Insulin Pump (At1Home)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2016-07-28
Completion: 2018-07-28
Conditions
Type 1 Diabetes
Interventions
OTHER
No Results Yet
NCT02747303 | RECRUITING | PHASE2
166 Participants

Frameless Stereotactic Radiosurgery for Intact Brain Metastases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-09-05
Completion: 2028-08-22
Conditions
Brain Metastases
Interventions
PROCEDURE
No Results Yet
NCT02734537 | RECRUITING | PHASE2
189 Participants

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2016-11-23
Completion: 2027-12-31
Conditions
Head and Neck Squamous Cell Carcinoma Hypopharyngeal Squamous Cell Carcinoma Laryngeal Squamous Cell Carcinoma Laryngeal Squamous Cell Carcinoma, Spindle Cell Variant Lip and Oral Cavity Squamous Cell Carcinoma p16INK4a Negative Oropharyngeal Squamous Cell Carcinoma Stage III Hypopharyngeal Carcinoma AJCC v8 Stage III Laryngeal Cancer AJCC v8 Stage III Lip and Oral Cavity Cancer AJCC v8 Stage III Oral Cavity Verrucous Carcinoma Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 Stage IVA Hypopharyngeal Carcinoma AJCC v8 Stage IVA Laryngeal Cancer AJCC v8 Stage IVA Lip and Oral Cavity Cancer AJCC v8 Stage IVA Oral Cavity Verrucous Carcinoma Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Interventions
DRUG RADIATION OTHER
No Results Yet
NCT02719106 | COMPLETED
1000 Participants

IRIS Ultimaster Cohort in the IRIS-DES Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2016-07-20
Completion: 2020-07-24
Conditions
Coronary Artery Disease
Interventions
DEVICE
No Results Yet
NCT02595424 | ACTIVE_NOT_RECRUITING | PHASE2
67 Participants

Cisplatin and Etoposide Versus Temozolomide and Capecitabine in Patients With Advanced Poorly Differentiated (G3) Non-Small Cell Gastrointestinal Neuroendocrine Carcinomas

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2016-04-06
Completion: 2025-04-23
Conditions
Gastric Neuroendocrine Carcinoma Intestinal Neuroendocrine Carcinoma Pancreatic Neuroendocrine Carcinoma
Interventions
DRUG OTHER
No Results Yet
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