Physiological Constraints Associated With Trail Running

NCT ID: NCT03712592

Last Updated: 2025-12-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

83 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-07-23

Study Completion Date

2018-09-05

Brief Summary

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The practice of mountain running or "trail" is in full development in France and elsewhere in the world. This sporting practice associates specific physiological constraints related in particular to the duration of the efforts made (several hours) and to the ground (important elevation, technical ground, average altitude). Some studies have allowed the last 10 years to initiate the exploration of the physiological consequences of this type of practice, especially from a muscular point of view. However, some important questions remain to be clarified such as the impact of these sports events on fatigue and muscle recovery, cardiovascular, energy and water balance disturbances caused, induced sleep changes and the kinetics of recovery of the various parameters. . These elements remain in particular to be studied in very different racing contexts as currently developed by the organizers, namely race in one stage from long to very long distances (40 to 160 km) and race in stages (4 days, 4 x 40 km) as encountered in the Grenoble UT4M race (Ultra Tour des 4 Massifs).

Detailed Description

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Conditions

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Muscle Fatigue

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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160km

Group Type EXPERIMENTAL

Pre and post running evaluations

Intervention Type OTHER

Each visit will include a series of neuromuscular, cardiovascular, blood glucose and body composition evaluations will be performed. The subjects will provide some information about their muscular pain and their food and water intake.

Finally, for the study of sleep that only concerns participants in the 4x40 km race, a home sleep registration banner will be given to each participant of the event step by step at the arrival of each stage in order to study sleep the next night as well as 2 nights after the arrival of the last stage.

40km

Group Type EXPERIMENTAL

Pre and post running evaluations

Intervention Type OTHER

Each visit will include a series of neuromuscular, cardiovascular, blood glucose and body composition evaluations will be performed. The subjects will provide some information about their muscular pain and their food and water intake.

Finally, for the study of sleep that only concerns participants in the 4x40 km race, a home sleep registration banner will be given to each participant of the event step by step at the arrival of each stage in order to study sleep the next night as well as 2 nights after the arrival of the last stage.

100km

Group Type EXPERIMENTAL

Pre and post running evaluations

Intervention Type OTHER

Each visit will include a series of neuromuscular, cardiovascular, blood glucose and body composition evaluations will be performed. The subjects will provide some information about their muscular pain and their food and water intake.

Finally, for the study of sleep that only concerns participants in the 4x40 km race, a home sleep registration banner will be given to each participant of the event step by step at the arrival of each stage in order to study sleep the next night as well as 2 nights after the arrival of the last stage.

4x40km

Group Type EXPERIMENTAL

Pre and post running evaluations

Intervention Type OTHER

Each visit will include a series of neuromuscular, cardiovascular, blood glucose and body composition evaluations will be performed. The subjects will provide some information about their muscular pain and their food and water intake.

Finally, for the study of sleep that only concerns participants in the 4x40 km race, a home sleep registration banner will be given to each participant of the event step by step at the arrival of each stage in order to study sleep the next night as well as 2 nights after the arrival of the last stage.

Interventions

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Pre and post running evaluations

Each visit will include a series of neuromuscular, cardiovascular, blood glucose and body composition evaluations will be performed. The subjects will provide some information about their muscular pain and their food and water intake.

Finally, for the study of sleep that only concerns participants in the 4x40 km race, a home sleep registration banner will be given to each participant of the event step by step at the arrival of each stage in order to study sleep the next night as well as 2 nights after the arrival of the last stage.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Man or woman
* 18-55 years
* Absence of chronic cardiovascular, respiratory, metabolic or neuromuscular disease
* \> 3 years of trail running (at least 1 race\> 40 km / year completed and a race\> 100 km completed (trail group 160 km)
* Medical certificate of no contraindication to the practice of the trail
* Subjects available in Grenoble before and within 15 days after the race
* Subjects affiliated to a social security scheme
* Subjects able to sign informed consent.

Exclusion Criteria

* Cardiorespiratory, metabolic and neurological diseases
* Non-Echogenic Subjects
* Subjects with chronic sleep disorders
* Psychiatric pathologies or ATCD of behavioral disorders
* Persons refusing to sign the information sheet and the participation agreement,
* persons under guardianship or not subject to a social security scheme,
* Pregnant woman, parturient, breastfeeding mother
* Person deprived of liberty by judicial or administrative decision,
* Person subject to a legal protection measure, who can not be included in clinical trials.
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Grenoble Alps

OTHER

Sponsor Role collaborator

University Hospital, Grenoble

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU Grenoble-Alpes

Grenoble, , France

Site Status

Countries

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France

References

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Besson T, Rossi J, LE Roux Mallouf T, Marechal M, Doutreleau S, Verges S, Millet GY. Fatigue and Recovery after Single-Stage versus Multistage Ultramarathon Running. Med Sci Sports Exerc. 2020 Aug;52(8):1691-1698. doi: 10.1249/MSS.0000000000002303.

Reference Type RESULT
PMID: 32079919 (View on PubMed)

Other Identifiers

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38RC18.096

Identifier Type: -

Identifier Source: org_study_id