Effects of Preoperative Rehabilitation in Patients Resected for Lung Cancer

NCT ID: NCT03020251

Last Updated: 2025-12-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-05-12

Study Completion Date

2026-02-28

Brief Summary

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This randomized controlled trial will evaluate the effect of a preoperative rehabilitation program at home in patients resected for lung cancer, comparing a control group (C group) receiving only chest physiotherapy and a rehabilitation group (R group) receiving both a training program at home and chest physiotherapy

Detailed Description

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Conditions

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Lungcancer

Keywords

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preoperative rehabilitation program chest physiotherapy lung cancer resection

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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control group (C group)

patient will receive preoperative chest physiotherapy (standard supportive care)

Group Type ACTIVE_COMPARATOR

preoperative chest physiotherapy

Intervention Type OTHER

preoperative chest physiotherapy : 5 sessions per week during 3 weeks

rehabilitation group (R group)

patient will receive preoperative chest physiotherapy and a preoperative rehabilitation program at home (exercise training)

Group Type EXPERIMENTAL

preoperative chest physiotherapy

Intervention Type OTHER

preoperative chest physiotherapy : 5 sessions per week during 3 weeks

preoperative rehabilitation program

Intervention Type OTHER

exercise training at home : 5 sessions per week during 3 weeks

Interventions

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preoperative chest physiotherapy

preoperative chest physiotherapy : 5 sessions per week during 3 weeks

Intervention Type OTHER

preoperative rehabilitation program

exercise training at home : 5 sessions per week during 3 weeks

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients diagnosed for lung cancer (or highly suspicious for cancer tumor) eligible for resection surgery (lobectomy or pneumonectomy)
* Age \> 18 years
* Presence of Chronic Obstructive Pulmonary Disease (COPD) stages 2-4 of Gold (forced expiratory volume (FEV )/ forced vital capacity (FVC) \<70%, FEV \<80% of predicted) and Exertional dyspnea stage MMRC (Medical Research Council) \> 1
* Patients must provide written consent
* Member of social security scheme

Exclusion Criteria

* Patients refusing to participate
* COPD stage 1 Gold (VEMS \>= 80% of the theoretical value)
* Presenting an operating contraindication during the initial maximal exercise test
* Presenting cardiac or vascular contraindication to achieve the readaptation program
* Patient living alone at home
* Patient with ventilatory assistance at home (oxygen therapy or noninvasive ventilation (NIV))
* With exercise hypoventilation (PaCO2 \>45 mmHg)
* Cognitive difficulty
* unable major
* pregnancy,
* patients deprived of liberty by a court or administrative decision
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Jean Perrin

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Marc FILAIRE, Pr

Role: PRINCIPAL_INVESTIGATOR

Centre Jean Perrin

Locations

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CHU Clermont Ferrand, Gabriel Montpied, service de médecine du sport et explorations fonctionnelles,

Clermont-Ferrand, , France

Site Status

Centre de Recherche en Nutrition Humaine

Clermont-Ferrand, , France

Site Status

Centre Jean Perrin

Clermont-Ferrand, , France

Site Status

CHU Grenoble, Hôpital Michallon

Grenoble, , France

Site Status

Hospices Civiles de Lyon, groupement hospitalier Est, Hopital Louis Pradel

Lyon, , France

Site Status

CHU Saint-Etienne, CHU Hopital Nord

Saint-Etienne, , France

Site Status

Countries

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France

References

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Laurent H, Galvaing G, Thivat E, Coudeyre E, Aubreton S, Richard R, Kwiatkowski F, Costes F, Filaire M. Effect of an intensive 3-week preoperative home rehabilitation programme in patients with chronic obstructive pulmonary disease eligible for lung cancer surgery: a multicentre randomised controlled trial. BMJ Open. 2017 Nov 12;7(11):e017307. doi: 10.1136/bmjopen-2017-017307.

Reference Type DERIVED
PMID: 29133320 (View on PubMed)

Other Identifiers

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2016-A00622-49

Identifier Type: -

Identifier Source: org_study_id