Clinical Trials

Showing trials with last updates posted in 2025.

NCT06119061 | RECRUITING | PHASE4
20 Participants

Telavancin Blood and Cerebrospinal Fluid Concentrations in Patients With External Ventricular Drainage

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-07-02
Completion: 2026-12-31
Conditions
Subarachnoid Hemorrhage, Aneurysmal
Interventions
DRUG
No Results Yet
NCT06117527 | RECRUITING
50 Participants

Placental Learning Model for Neurovascular Microsurgery for the Management of Intracranial Aneurysms

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2020-07-16
Completion: 2028-02-29
Conditions
Intracranial Aneurysm
No Results Yet
NCT06109948 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1
46 Participants

Study to Assess the Safety, Tolerability, PK and PD of ABX1100

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-10-19
Completion: 2026-02-28
Conditions
Healthy Late Onset Pompe Disease
Interventions
DRUG
No Results Yet
NCT06075524 | RECRUITING
500 Participants

Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2015-06-15
Completion: 2026-12-31
Conditions
Clinical Stage III Cutaneous Melanoma AJCC v8 Clinical Stage IV Cutaneous Melanoma AJCC v8 Locally Advanced Lung Carcinoma Locally Advanced Malignant Solid Neoplasm Locally Advanced Melanoma Metastatic Lung Carcinoma Metastatic Malignant Solid Neoplasm Metastatic Melanoma Stage III Lung Cancer AJCC v8 Stage IV Lung Cancer AJCC v8
Interventions
PROCEDURE OTHER
No Results Yet
NCT06073158 | COMPLETED | NA
6 Participants

Molecular Signatures of Esophageal Atresia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-09-01
Completion: 2024-03-04
Conditions
Esophageal Atresia
Interventions
PROCEDURE
No Results Yet
NCT06071299 | ACTIVE_NOT_RECRUITING | NA
200 Participants

Impact of Family-Centered Care for Intimate Partner Violence (IPV)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-01-10
Completion: 2026-02-15
Conditions
Intimate Partner Violence
Interventions
BEHAVIORAL
No Results Yet
NCT06057948 | RECRUITING | PHASE2
94 Participants

A Study of a Vaccine in Combination With Beta-glucan in People With Neuroblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-09-21
Completion: 2026-03-21
Conditions
Neuroblastoma High-risk Neuroblastoma Metastatic Neuroblastoma
Interventions
BIOLOGICAL DIETARY_SUPPLEMENT
No Results Yet
NCT06054607 | COMPLETED | NA
21 Participants

Effect of Short-chain Fatty Acids on Aerobic Endurance

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-07-21
Completion: 2025-05-01
Conditions
Aerobic Endurance Metabolism
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT06053749 | ACTIVE_NOT_RECRUITING
4 Participants

An Observational Study to Learn About the Interferon-beta Exposure of Pregnant Women During the Second and Third Trimester in Finland and Sweden

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2024-03-20
Completion: 2026-03-31
Conditions
Multiple Sclerosis (MS)
Interventions
DRUG
No Results Yet
NCT06052254 | RECRUITING | PHASE2
150 Participants

Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's Type

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-09-16
Completion: 2027-01-31
Conditions
Agitation
Interventions
DRUG
No Results Yet
NCT06032143 | ACTIVE_NOT_RECRUITING | NA
120 Participants

Doulas as Environmental Educators and Partners Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-10-20
Completion: 2026-01-30
Conditions
Health Knowledge, Attitudes, Practice
Interventions
BEHAVIORAL
No Results Yet
NCT06029972 | RECRUITING | PHASE2
176 Participants

Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-12-05
Completion: 2026-04-30
Conditions
Ulcerative Colitis
Interventions
DRUG
No Results Yet
NCT06024317 | NOT_YET_RECRUITING | NA
800 Participants

Leveraging Community Health Workers and a Digital Health System to Improve the Timeliness of Child Well Visits

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-03-01
Completion: 2027-07-31
Conditions
Short Message Service (SMS) Incentives Knowledge, Attitudes, Practice Preventive Services
Interventions
BEHAVIORAL
No Results Yet
NCT06019767 | COMPLETED | NA
59 Participants

Peer-led Trauma Therapy for Re-entry

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-11-14
Completion: 2025-12-12
Conditions
PTSD
Interventions
BEHAVIORAL
No Results Yet
NCT06015009 | COMPLETED | NA
40 Participants

Symptom Management App for Children at the Early Stage of Cancer Survivorship and Their Caregivers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-08-17
Completion: 2025-01-02
Conditions
Oncology Survivorship
Interventions
OTHER
No Results Yet
NCT06012149 | ACTIVE_NOT_RECRUITING | NA
208 Participants

Braining: Implementation of Physical Exercise for Patients in Specialist Psychiatry

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-09-27
Completion: 2026-06-30
Conditions
Mental Disorders
Interventions
BEHAVIORAL
No Results Yet
NCT06008938 | RECRUITING
500 Participants

An Observational Cohort Study to Characterize the Effectiveness and Safety of HEMGENIX® in Patients With Hemophilia B

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-06-15
Completion: 2043-08-01
Conditions
Hemophilia B
Interventions
GENETIC BIOLOGICAL
No Results Yet
NCT05991622 | ACTIVE_NOT_RECRUITING | PHASE2
40 Participants

Combined Injectable Treatment for HIV and OUD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-04-01
Completion: 2025-08-27
Conditions
Human Immunodeficiency Virus Opioid Use Disorder
Interventions
DRUG
No Results Yet
NCT05989711 | COMPLETED | PHASE2
212 Participants

IMPACT TRIAL: Efficacy and Safety of Pemvidutide in Subjects With Nonalcoholic Steatohepatitis (NASH)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-07-27
Completion: 2025-04-29
Conditions
Non-Alcoholic Steatohepatitis (NASH)
Interventions
DRUG
No Results Yet
NCT05983991 | RECRUITING | NA
150 Participants

Study for Characterisation of Predictive Parameters of Clonal Evolution in Subjects With GATA2 Germline Mutation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-12-07
Completion: 2033-12-31
Conditions
GATA2 Gene Mutation
Interventions
OTHER
No Results Yet
NCT05973383 | NOT_YET_RECRUITING
1500 Participants

Evaluation of a Personalised Digital Intervention (EviBody) for Healthy and Sustained Lifestyle Behaviors and Well-being Among Adults: a Real-world Quasi-experimental Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2026-01-01
Completion: 2026-12-31
Conditions
Well-being
Interventions
BEHAVIORAL
No Results Yet
NCT05963984 | COMPLETED | PHASE2
60 Participants

A Study of Samuraciclib in Combination With Fulvestrant in Metastatic or Locally Advanced Breast Cancer in Adult Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-11-16
Completion: 2025-03-20
Conditions
Metastatic Breast Cancer Locally Advanced Breast Cancer Breast Cancer
Interventions
DRUG
No Results Yet
NCT05958043 | COMPLETED | NA
20 Participants

Performance of CAD/CAM Milled and 3D-printed Full-arch Implant-supported Provisionals Restorations

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-03-01
Completion: 2025-05-01
Conditions
Edentulous Jaw Dental Prosthesis Complication Dental Prosthesis Failure
Interventions
DEVICE
No Results Yet
NCT05954312 | RECRUITING | PHASE1
290 Participants

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-07-28
Completion: 2030-08-31
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT05952752 | COMPLETED | NA
382 Participants

Dexemedetomidine on Shivering Cesarean Section Under Spinal Anesthesia A Randomized Clinical Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-07-20
Completion: 2023-09-25
Conditions
Postoperative Shivering
Interventions
OTHER
No Results Yet
NCT05947539 | ENROLLING_BY_INVITATION | NA
80 Participants

Improving HIV Care Engagement Among Ugandan Adolescent Girls and Young Women: The Kisoboka Mukwano Intervention

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-07-01
Completion: 2026-10-30
Conditions
HIV-infection/Aids Intimate Partner Violence Domestic Violence Alcohol Use Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT05932745 | RECRUITING | NA
66 Participants

Effects of Novel E-cigarette Constituents on Adults TCORS 3.0

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-06-20
Completion: 2026-05-31
Conditions
Nicotine Use Disorder
Interventions
OTHER
No Results Yet
NCT05923983 | COMPLETED | NA
783 Participants

DETECT-IP: a Clinical Decision Support System and Intelligent Procedures to Counter Some Adverse Drug Events in Older Hospital Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-10-02
Completion: 2024-10-03
Conditions
Patient Acceptance of Health Care Acute Renal Failure
Interventions
OTHER
No Results Yet
NCT05919979 | COMPLETED | NA
25 Participants

Effect of a Physical Exercise Session Performed During a 24-34 Hour Fasting Period on Energy Metabolism and Cognitive Function in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-05-29
Completion: 2025-06-11
Conditions
Energy Metabolism
Interventions
BEHAVIORAL
No Results Yet
NCT05919472 | COMPLETED | NA
180 Participants

Effects of Oral Iron Supplementation on Vaccine Response in Iron Deficient Kenyan Women

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-07-01
Completion: 2024-07-16
Conditions
Iron Deficiency Anemia
Interventions
DIETARY_SUPPLEMENT BIOLOGICAL
No Results Yet
NCT05912582 | NOT_YET_RECRUITING
60 Participants

Prospective Study for Molecular Biomarkers and Spatial Transcriptomics of Nasopharyngeal Carcinoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-25
Completion: 2027-06-25
Conditions
Nasopharyngeal Carcinoma
Interventions
RADIATION
No Results Yet
NCT05899998 | ACTIVE_NOT_RECRUITING | NA
40 Participants

Bright IDEAS for Pediatric Palliative Care: A Problem-Solving Skills Intervention to Empower Parent Resilience

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-08-08
Completion: 2026-05-31
Conditions
Psychological Distress Quality of Life
Interventions
BEHAVIORAL
No Results Yet
NCT05892432 | COMPLETED | PHASE2
50 Participants

Clinical Trial of Rybelsus (Semaglutide) Among Adults With Alcohol Use Disorder (AUD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-01-11
Completion: 2025-11-04
Conditions
Alcohol Use Disorder
Interventions
DRUG
No Results Yet
NCT05866419 | RECRUITING | NA
90 Participants

Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-11-27
Completion: 2026-05-31
Conditions
Spinal Muscular Atrophy Spine Deformity Scoliosis
Interventions
DEVICE
No Results Yet
NCT05856838 | RECRUITING | NA
30 Participants

NovaSure Study: Endometrial Ablation in Women With Heavy Menstrual Bleeding

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-11-24
Completion: 2026-01-01
Conditions
Menstrual Bleeding, Heavy
Interventions
DEVICE
No Results Yet
NCT05836025 | ACTIVE_NOT_RECRUITING | PHASE2
50 Participants

Effect of Rapamycin in Ovarian Aging

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-06-01
Completion: 2025-10-21
Conditions
Perimenopausal
Interventions
DRUG OTHER
No Results Yet
NCT05818709 | COMPLETED | PHASE3
61 Participants

A Study to Assess Adverse Events and Effectiveness of HAC 22L Injection for Mid-Face Volume in Adult Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-06-14
Completion: 2025-12-05
Conditions
Facial Volume Deficit
Interventions
DEVICE
No Results Yet
NCT05816187 | COMPLETED | NA
78 Participants

Efficacy and Safety of Supervised Therapeutic Exercise in Cancer Patients With and Without Concurrent Treatment.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-15
Completion: 2025-09-01
Conditions
Breast Cancer Colon Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT05812053 | RECRUITING | NA
30 Participants

Comparative Evaluation of Eggshell Powder in Primary Teeth Pulpotomy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-04-01
Completion: 2026-01-31
Conditions
Pulpitis Reversible Pulp Exposure, Dental
Interventions
PROCEDURE RADIATION
No Results Yet
NCT05804227 | RECRUITING | EARLY_PHASE1
20 Participants

Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Gliomas

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-04-20
Completion: 2027-09-22
Conditions
Gliomas
Interventions
DRUG
No Results Yet
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