Clinical Trials

NCT05991622 | ACTIVE_NOT_RECRUITING | PHASE2

40 Participants

Combined Injectable Treatment for HIV and OUD

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-04-01

Completion: 2025-08-27

Conditions

Human Immunodeficiency Virus Opioid Use Disorder

Interventions

DRUG

No Results Yet

NCT05989711 | COMPLETED | PHASE2

212 Participants

IMPACT TRIAL: Efficacy and Safety of Pemvidutide in Subjects With Nonalcoholic Steatohepatitis (NASH)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-07-27

Completion: 2025-04-29

Conditions

Non-Alcoholic Steatohepatitis (NASH)

Interventions

DRUG

No Results Yet

NCT05987241 | RECRUITING | PHASE2/PHASE3

992 Participants

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2024-02-02

Completion: 2030-09-02

Conditions

Muscle Invasive Bladder Urothelial Carcinoma Muscle Invasive Renal Pelvis Urothelial Carcinoma Muscle Invasive Ureter Urothelial Carcinoma Muscle Invasive Urethral Urothelial Carcinoma Stage II Bladder Urothelial Carcinoma AJCC v6 and v7 Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 Stage IV Bladder Urothelial Carcinoma AJCC v7

Interventions

PROCEDURE OTHER BIOLOGICAL

No Results Yet

NCT05983991 | RECRUITING | NA

150 Participants

Study for Characterisation of Predictive Parameters of Clonal Evolution in Subjects With GATA2 Germline Mutation

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-12-07

Completion: 2033-12-31

Conditions

GATA2 Gene Mutation

Interventions

OTHER

No Results Yet

NCT05973383 | NOT_YET_RECRUITING

1500 Participants

Evaluation of a Personalised Digital Intervention (EviBody) for Healthy and Sustained Lifestyle Behaviors and Well-being Among Adults: a Real-world Quasi-experimental Study

Study Type: OBSERVATIONAL

Last Updated: 2025-12-26

Start Date: 2026-01-01

Completion: 2026-12-31

Conditions

Well-being

Interventions

BEHAVIORAL

No Results Yet

NCT05969002 | RECRUITING

36 Participants

Pilot Prospective Study for PET-CT Imaging in Participants With Relapsed/Refractory Acute Leukemias

Study Type: OBSERVATIONAL

Last Updated: 2025-12-26

Start Date: 2023-08-25

Completion: 2025-12-31

Conditions

B Cell Acute Lymphoblastic Leukemia Relapsed/Refractory

No Results Yet

NCT05963984 | COMPLETED | PHASE2

60 Participants

A Study of Samuraciclib in Combination With Fulvestrant in Metastatic or Locally Advanced Breast Cancer in Adult Participants

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-11-16

Completion: 2025-03-20

Conditions

Metastatic Breast Cancer Locally Advanced Breast Cancer Breast Cancer

Interventions

DRUG

No Results Yet

NCT05958043 | COMPLETED | NA

20 Participants

Performance of CAD/CAM Milled and 3D-printed Full-arch Implant-supported Provisionals Restorations

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-03-01

Completion: 2025-05-01

Conditions

Edentulous Jaw Dental Prosthesis Complication Dental Prosthesis Failure

Interventions

DEVICE

No Results Yet

NCT05954312 | RECRUITING | PHASE1

290 Participants

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-07-28

Completion: 2030-08-31

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT05952752 | COMPLETED | NA

382 Participants

Dexemedetomidine on Shivering Cesarean Section Under Spinal Anesthesia A Randomized Clinical Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-07-20

Completion: 2023-09-25

Conditions

Postoperative Shivering

Interventions

OTHER

No Results Yet

NCT05947539 | ENROLLING_BY_INVITATION | NA

80 Participants

Improving HIV Care Engagement Among Ugandan Adolescent Girls and Young Women: The Kisoboka Mukwano Intervention

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-07-01

Completion: 2026-10-30

Conditions

HIV-infection/Aids Intimate Partner Violence Domestic Violence Alcohol Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT05932745 | RECRUITING | NA

66 Participants

Effects of Novel E-cigarette Constituents on Adults TCORS 3.0

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2025-06-20

Completion: 2026-05-31

Conditions

Nicotine Use Disorder

Interventions

OTHER

No Results Yet

NCT05923983 | COMPLETED | NA

783 Participants

DETECT-IP: a Clinical Decision Support System and Intelligent Procedures to Counter Some Adverse Drug Events in Older Hospital Patients

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-10-02

Completion: 2024-10-03

Conditions

Patient Acceptance of Health Care Acute Renal Failure

Interventions

OTHER

No Results Yet

NCT05919979 | COMPLETED | NA

25 Participants

Effect of a Physical Exercise Session Performed During a 24-34 Hour Fasting Period on Energy Metabolism and Cognitive Function in Healthy Adults

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-05-29

Completion: 2025-06-11

Conditions

Energy Metabolism

Interventions

BEHAVIORAL

No Results Yet

NCT05919472 | COMPLETED | NA

180 Participants

Effects of Oral Iron Supplementation on Vaccine Response in Iron Deficient Kenyan Women

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-07-01

Completion: 2024-07-16

Conditions

Iron Deficiency Anemia

Interventions

DIETARY_SUPPLEMENT BIOLOGICAL

No Results Yet

NCT05912582 | NOT_YET_RECRUITING

60 Participants

Prospective Study for Molecular Biomarkers and Spatial Transcriptomics of Nasopharyngeal Carcinoma

Study Type: OBSERVATIONAL

Last Updated: 2025-12-26

Start Date: 2025-12-25

Completion: 2027-06-25

Conditions

Nasopharyngeal Carcinoma

Interventions

RADIATION

No Results Yet

NCT05909202 | RECRUITING | NA

218 Participants

A Nature-Based Virtual Reality (VR) Intervention in Family Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2024-06-05

Completion: 2027-09-01

Conditions

Neoplasm Caregivers

Interventions

DEVICE

No Results Yet

NCT05904080 | RECRUITING | PHASE2

50 Participants

Testing Nivolumab and Ipilimumab Immunotherapy With or Without the Targeted Drug Cabozantinib in Recurrent, Metastatic, or Incurable Nasopharyngeal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2024-02-19

Completion: 2028-06-16

Conditions

Metastatic Nasopharyngeal Carcinoma Recurrent Nasopharyngeal Carcinoma Stage IV Nasopharyngeal Carcinoma AJCC v8

Interventions

PROCEDURE DRUG BIOLOGICAL

No Results Yet

NCT05899998 | ACTIVE_NOT_RECRUITING | NA

40 Participants

Bright IDEAS for Pediatric Palliative Care: A Problem-Solving Skills Intervention to Empower Parent Resilience

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-08-08

Completion: 2026-05-31

Conditions

Psychological Distress Quality of Life

Interventions

BEHAVIORAL

No Results Yet

NCT05898646 | RECRUITING | PHASE2

96 Participants

Daratumumab Maintenance Therapy for Improving Survival in Patients With Light Chain Amyloidosis, EMILIA Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-07-17

Completion: 2026-12-31

Conditions

AL Amyloidosis

Interventions

PROCEDURE BIOLOGICAL OTHER

No Results Yet

NCT05896839 | RECRUITING | PHASE1/PHASE2

16 Participants

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2024-07-24

Completion: 2027-01-31

Conditions

Clinical Stage III Cutaneous Melanoma AJCC v8 Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8 Clinical Stage IV Cutaneous Melanoma AJCC v8 Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8 Metastatic Basal Cell Carcinoma Metastatic Carcinoma in the Skin Metastatic Melanoma Metastatic Merkel Cell Carcinoma Metastatic Skin Squamous Cell Carcinoma Unresectable Basal Cell Carcinoma Unresectable Melanoma Unresectable Merkel Cell Carcinoma Unresectable Skin Squamous Cell Carcinoma

Interventions

PROCEDURE BIOLOGICAL DRUG

No Results Yet

NCT05892432 | COMPLETED | PHASE2

50 Participants

Clinical Trial of Rybelsus (Semaglutide) Among Adults With Alcohol Use Disorder (AUD)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2024-01-11

Completion: 2025-11-04

Conditions

Alcohol Use Disorder

Interventions

DRUG

No Results Yet

NCT05866419 | RECRUITING | NA

90 Participants

Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-11-27

Completion: 2026-05-31

Conditions

Spinal Muscular Atrophy Spine Deformity Scoliosis

Interventions

DEVICE

No Results Yet

NCT05859334 | RECRUITING | PHASE2

35 Participants

Testing the Anti-cancer Drug Erdafitinib for Brain Cancers That Have Returned or Progressed Following Treatment

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2024-01-04

Completion: 2026-10-23

Conditions

Recurrent Glioma Recurrent WHO Grade 2 Glioma Recurrent WHO Grade 3 Glioma Recurrent WHO Grade 4 Glioma

Interventions

PROCEDURE DRUG

No Results Yet

NCT05856838 | RECRUITING | NA

30 Participants

NovaSure Study: Endometrial Ablation in Women With Heavy Menstrual Bleeding

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-11-24

Completion: 2026-01-01

Conditions

Menstrual Bleeding, Heavy

Interventions

DEVICE

No Results Yet

NCT05836025 | ACTIVE_NOT_RECRUITING | PHASE2

50 Participants

Effect of Rapamycin in Ovarian Aging

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-06-01

Completion: 2025-10-21

Conditions

Perimenopausal

Interventions

DRUG OTHER

No Results Yet

NCT05827887 | RECRUITING

200 Participants

An Observational Study to Assess Ubrogepant Tablets and Atogepant Tablets to Treat Migraine in Adult Participants

Study Type: OBSERVATIONAL

Last Updated: 2025-12-26

Start Date: 2023-06-25

Completion: 2026-02-28

Conditions

Migraine

No Results Yet

NCT05818709 | COMPLETED | PHASE3

61 Participants

A Study to Assess Adverse Events and Effectiveness of HAC 22L Injection for Mid-Face Volume in Adult Participants

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-06-14

Completion: 2025-12-05

Conditions

Facial Volume Deficit

Interventions

DEVICE

No Results Yet

NCT05816187 | COMPLETED | NA

78 Participants

Efficacy and Safety of Supervised Therapeutic Exercise in Cancer Patients With and Without Concurrent Treatment.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-03-15

Completion: 2025-09-01

Conditions

Breast Cancer Colon Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT05814627 | ACTIVE_NOT_RECRUITING | PHASE3

487 Participants

Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-06-15

Completion: 2026-07-31

Conditions

Rheumatoid Arthritis

Interventions

DRUG

No Results Yet

NCT05812053 | RECRUITING | NA

30 Participants

Comparative Evaluation of Eggshell Powder in Primary Teeth Pulpotomy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-04-01

Completion: 2026-01-31

Conditions

Pulpitis Reversible Pulp Exposure, Dental

Interventions

PROCEDURE RADIATION

No Results Yet

NCT05804227 | RECRUITING | EARLY_PHASE1

20 Participants

Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Gliomas

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-04-20

Completion: 2027-09-22

Conditions

Gliomas

Interventions

DRUG

No Results Yet

NCT05798676 | RECRUITING

130 Participants

Maternal Characteristics Associated With Child Growth and Adiposity

Study Type: OBSERVATIONAL

Last Updated: 2025-12-26

Start Date: 2019-05-02

Completion: 2028-03-31

Conditions

Obesity Obesity, Infant

Interventions

OTHER

No Results Yet

NCT05782907 | ACTIVE_NOT_RECRUITING | PHASE3

122 Participants

Study to Assess Adverse Events, Change in Disease Activity, and How Oral Upadacitinib Moves Through the Body of Pediatric Participants With Moderately to Severely Active Ulcerative Colitis.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-11-06

Completion: 2028-08-31

Conditions

Ulcerative Colitis

Interventions

DRUG

No Results Yet

NCT05779462 | RECRUITING

52 Participants

ENDOMETRIOSIS - MRI

Study Type: OBSERVATIONAL

Last Updated: 2025-12-26

Start Date: 2023-05-23

Completion: 2026-07-31

Conditions

Endometriosis Mobility Limitation Magnetic Resonance Imaging Diagnosis Pelvis Comparative Study

Interventions

OTHER

No Results Yet

NCT05777993 | ENROLLING_BY_INVITATION | PHASE4

6 Participants

A Study to Provide Continued Access to Mitapivat for Participants Who Previously Completed an Agios-Sponsored Mitapivat Study

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-07-06

Completion: 2029-08-31

Conditions

Pyruvate Kinase Deficiency Anemia, Hemolytic

Interventions

DRUG

No Results Yet

NCT05774678 | RECRUITING | PHASE3

126 Participants

Trial Of PreoperAtive Radiation (TOPAz): A Randomized Trial Comparing Hypofractionated Versus Conventionally Fractionated Preoperative Radiation Followed by Mastectomy With Immediate Autologous Breast Reconstruction With Integrated Nanomechanical Biomarker Evaluation

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-04-05

Completion: 2026-11-01

Conditions

Breast Cancer

Interventions

RADIATION OTHER

No Results Yet

NCT05774600 | COMPLETED | NA

641 Participants

Virtual Sun Safe Workplaces Ph II (SSW Works)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-06-01

Completion: 2025-02-25

Conditions

Skin Cancer Occupational Exposure

Interventions

BEHAVIORAL

No Results Yet

NCT05773274 | RECRUITING | PHASE2

100 Participants

Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2024-01-12

Completion: 2026-04-30

Conditions

Metastatic Digestive System Neuroendocrine Tumor G1 Metastatic Digestive System Neuroendocrine Tumor G2 Unresectable Digestive System Neuroendocrine Tumor G1 Unresectable Digestive System Neuroendocrine Tumor G2

Interventions

PROCEDURE DRUG OTHER

No Results Yet

NCT05765812 | RECRUITING | PHASE1/PHASE2

116 Participants

A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-05-15

Completion: 2028-09-30

Conditions

Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype Astrocytoma, Grade III

Interventions

DRUG RADIATION

No Results Yet