Clinical Trials Updated in 2025

NCT06686394 | RECRUITING | PHASE1/PHASE2

81 Participants

Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-02-26

Completion: 2030-04-18

Conditions

Breast Neoplasms Breast Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT06685757 | RECRUITING | PHASE3

120 Participants

A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2024-12-03

Completion: 2026-12-01

Conditions

Antibody-mediated Rejection

Interventions

DRUG

No Results Yet

NCT06683898 | COMPLETED | NA

50 Participants

The Role of Focus Strategies on Pilates

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2024-10-05

Completion: 2025-04-15

Conditions

Reaction Time Humans Exercise Therapy Exercise Movement Techniques Pilates

Interventions

OTHER

No Results Yet

NCT06681103 | COMPLETED | NA

1112 Participants

Intention to Change and Treatment-Seeking in Pathological Gamblers and Investors: An Experimental Study in Young Adults

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2024-12-20

Completion: 2025-06-30

Conditions

Gambling Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06680388 | RECRUITING | EARLY_PHASE1

15 Participants

CD19 CAR-T in the Treatment of Relapsed/Refractory Autoimmune Diseases

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2024-11-15

Completion: 2027-12-31

Conditions

Autoimmune Diseases

Interventions

DRUG

No Results Yet

NCT06678841 | RECRUITING | NA

700 Participants

ELEVATE-HFpEF Clinical Study

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-07-09

Completion: 2028-08-31

Conditions

Heart Failure With Preserved Ejection Fraction (HFpEF)

Interventions

DEVICE

No Results Yet

NCT06666192 | RECRUITING | NA

2067 Participants

The Ohio State University (OSU) SCREEN Community Program

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2024-03-12

Completion: 2029-12-31

Conditions

Breast Carcinoma Cervical Carcinoma Colorectal Carcinoma

Interventions

OTHER BEHAVIORAL PROCEDURE

No Results Yet

NCT06663319 | RECRUITING | PHASE1

170 Participants

A Study of JNJ-89402638 for Metastatic Colorectal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2024-10-15

Completion: 2028-02-25

Conditions

Unresectable Metastatic Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT06660563 | ACTIVE_NOT_RECRUITING | PHASE1

19 Participants

A Study of JNJ-80948543 in Combination With Other CD3 T-Cell Engagers in Participants With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (R/R B-Cell NHL)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2024-10-22

Completion: 2026-01-19

Conditions

Lymphoma, Non-Hodgkin

Interventions

DRUG

No Results Yet

NCT06658197 | NOT_YET_RECRUITING | PHASE3

850 Participants

Efficacy and Safety of Tenecteplase Bridging Mechanical Thrombectomy for Acute Large Vessel Occlusion Stroke

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-12-02

Completion: 2026-12-01

Conditions

Stroke, Ischemic Stroke, Acute Thrombosis, Brain Drug Effect

Interventions

DRUG

No Results Yet

NCT06640283 | RECRUITING | PHASE2

150 Participants

Dynamic ctDNA Assessment in Cervical and Anal Canal Tumors: Optimizing Follow-up and Clinical Outcomes

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-03-14

Completion: 2026-12-31

Conditions

HPV-Related Carcinoma Uterine Cervical Cancer Anal Canal Cancer HPV-Related Anal Squamous Cell Carcinoma HPV-Related Cervical Carcinoma

Interventions

DIAGNOSTIC_TEST DRUG

No Results Yet

NCT06636032 | RECRUITING | PHASE1/PHASE2

9 Participants

Dose Escalation of Allogeneic Adipose Derived Stroma/Stem Cells for the Treatment of Crohn's Fistula

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-03-12

Completion: 2027-09-30

Conditions

Crohn Disease

Interventions

DRUG

No Results Yet

NCT06626256 | WITHDRAWN | PHASE1

0 Participants

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-12-05

Completion: 2027-10-30

Conditions

Locally Advanced Cervical Carcinoma Locally Advanced Colorectal Carcinoma Locally Advanced Malignant Solid Neoplasm Locally Advanced Melanoma Locally Advanced Pancreatic Ductal Adenocarcinoma Locally Advanced Renal Cell Carcinoma Metastatic Cervical Carcinoma Metastatic Colorectal Carcinoma Metastatic Malignant Solid Neoplasm Metastatic Melanoma Metastatic Pancreatic Ductal Adenocarcinoma Metastatic Renal Cell Carcinoma Stage II Pancreatic Cancer AJCC v8 Stage III Cervical Cancer AJCC v8 Stage III Colorectal Cancer AJCC v8 Stage III Pancreatic Cancer AJCC v8 Stage III Renal Cell Cancer AJCC v8 Stage IV Cervical Cancer AJCC v8 Stage IV Colorectal Cancer AJCC v8 Stage IV Pancreatic Cancer AJCC v8 Stage IV Renal Cell Cancer AJCC v8 Unresectable Cervical Carcinoma Unresectable Colorectal Carcinoma Unresectable Malignant Solid Neoplasm Unresectable Melanoma Unresectable Pancreatic Ductal Adenocarcinoma Unresectable Renal Cell Carcinoma

Interventions

BIOLOGICAL PROCEDURE DRUG

No Results Yet

NCT06618287 | RECRUITING | PHASE1/PHASE2

416 Participants

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-02-04

Completion: 2031-02-26

Conditions

Lung Cancer Breast Cancer

Interventions

DRUG

No Results Yet

NCT06616623 | SUSPENDED | PHASE1

24 Participants

Vismodegib and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2024-12-31

Completion: 2026-12-31

Conditions

Metastatic Lung Non-Small Cell Carcinoma Recurrent Lung Non-Small Cell Carcinoma Stage IV Lung Cancer AJCC v8

Interventions

BIOLOGICAL PROCEDURE DRUG

No Results Yet

NCT06613516 | WITHDRAWN | PHASE2

0 Participants

Effect of Capivasertib on ctDNA in ER Positive Breast Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-02-01

Completion: 2025-09-16

Conditions

Breast Cancer Oestrogen Receptor Positive Breast Cancer

Interventions

DRUG

No Results Yet

NCT06612827 | RECRUITING

20 Participants

Development of Tumor Organoids From Undifferentiated Primary Carcinomas to Guide Therapeutic Decisions

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2025-03-05

Completion: 2028-12-15

Conditions

Undifferentiated Carcinoma

Interventions

OTHER

No Results Yet

NCT06610838 | RECRUITING

600 Participants

Effects of E-cigarette Use on Health

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2025-01-06

Completion: 2029-06-30

Conditions

Electronic Cigarette Use

Interventions

OTHER

No Results Yet

NCT06600321 | RECRUITING | PHASE1

158 Participants

A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2024-12-30

Completion: 2027-09-30

Conditions

Advanced Hepatocellular Carcinoma Metastatic Hepatocellular Carcinoma

Interventions

DRUG

No Results Yet

NCT06599736 | ACTIVE_NOT_RECRUITING | NA

25 Participants

A Study of RhinAer Stylus for Treating Chronic Rhinitis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2024-10-03

Completion: 2025-12-31

Conditions

Chronic Rhinitis

Interventions

DEVICE

No Results Yet

NCT06598943 | RECRUITING | PHASE2

140 Participants

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2024-10-10

Completion: 2027-12-31

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2026-01-31

Completion: 2027-03-31

Conditions

B-ALL Hematologic Malignancy Solid Tumor

No Results Yet

NCT06567314 | RECRUITING | PHASE2

24 Participants

Phase 2 Study of Ivonescimab in Patients With Cutaneous Squamous Cell Carcinoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2024-12-02

Completion: 2028-09-01

Conditions

Cutaneous Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT06560918 | RECRUITING | NA

27 Participants

Self-efficacy-based Auditory Rehabilitation With Over-the-Counter Hearing Aids

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2024-10-30

Completion: 2026-01-31

Conditions

Hearing Loss, Sensorineural

Interventions

DEVICE

No Results Yet

NCT06554405 | COMPLETED | NA

28 Participants

Bilateral vs. Unilateral Neuromobilization in Carpal Tunnel Syndrome

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2024-08-31

Completion: 2025-05-30

Conditions

Carpal Tunnel Syndrome

Interventions

OTHER

No Results Yet

NCT06543914 | RECRUITING

1000 Participants

Observational Study of Oral Atogepant to Evaluate Real-World Effectiveness in Adult Participants With Migraine

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2024-11-26

Completion: 2029-02-28

Conditions

Migraine

No Results Yet

NCT06537934 | RECRUITING

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2024-12-19

Completion: 2026-12-23

Conditions

Focal Segmental Glomerulosclerosis Glomerulonephritis Minimal Lesion

Interventions

DRUG

No Results Yet