Clinical Trials

Showing trials with last updates posted in 2025.

NCT06218134 | COMPLETED | NA
3 Participants

Evaluate the Safety and Potential Efficacy of Human Wharton's Jelly-derived Mesenchymal Stem Cells With Charcot-Marie-Tooth Disease Type 1E

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-05-23
Completion: 2024-10-28
Conditions
Charcot-Marie-Tooth Disease, Type 1
Interventions
BIOLOGICAL
No Results Yet
NCT06211634 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
57 Participants

A Phase 1/2 Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-001 in Glanzmann Thrombasthenia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-12-13
Completion: 2027-08-31
Conditions
Glanzmann Thrombasthenia
Interventions
DRUG
No Results Yet
NCT06204887 | COMPLETED | NA
97 Participants

Effect of Irrigation-Activation Techniques on Healing in Large Periapical Lesions

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-11-01
Completion: 2023-02-27
Conditions
Effect of Irrigation Activation on Periapical Healing
Interventions
PROCEDURE
NCT06188481 | COMPLETED | NA
66 Participants

Efficacy of Whole-body Electromyostimulation (WB-EMS) Training in Participants With Pre-diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-01-23
Completion: 2025-12-17
Conditions
Pre-diabetes
Interventions
OTHER
No Results Yet
NCT06184126 | RECRUITING | NA
30 Participants

Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-11-01
Completion: 2026-09-30
Conditions
Sickle Cell Disease Vaso-occlusive Pain Episode in Sickle Cell Disease Acute Pain
Interventions
DEVICE OTHER
No Results Yet
NCT06170606 | RECRUITING | NA
200 Participants

POLARx Post Approval Study (POLARx PAS)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-06-28
Completion: 2026-05-31
Conditions
Paroxysmal Atrial Fibrillation
Interventions
DEVICE
No Results Yet
NCT06158841 | RECRUITING | PHASE3
380 Participants

Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-05-19
Completion: 2027-12-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06155786 | COMPLETED | NA
36 Participants

Cognitive Effects of tDCS and tRNS in Schizophrenia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-01-01
Completion: 2023-11-01
Conditions
Schizophrenia Cognitive Impairment
Interventions
DEVICE
No Results Yet
NCT06150157 | RECRUITING | PHASE1
220 Participants

A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-20
Completion: 2026-12-04
Conditions
Myeloproliferative Disorders Essential Thrombocythemia Neoplasms Myelofibrosis
Interventions
DRUG
No Results Yet
NCT06147258 | RECRUITING | NA
60 Participants

The Impact of Expressive Emotional Writing on Facilitating Grief Resolution in Adults With Spinal Cord Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-05-03
Completion: 2026-12-31
Conditions
Spinal Cord Injuries Transverse Myelitis
Interventions
BEHAVIORAL
No Results Yet
NCT06144242 | ACTIVE_NOT_RECRUITING | NA
90 Participants

Improving Antibiotic Use for ARIs in Urgent Care Clinics

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-01-01
Completion: 2025-06-30
Conditions
Antibacterial Agents Ambulatory Care
Interventions
BEHAVIORAL
No Results Yet
NCT06143293 | RECRUITING | NA
144 Participants

RESEARCH EVALUATING VAGAL EXCITATION AND ANATOMICAL LINKS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-15
Completion: 2026-08-01
Conditions
Epilepsy Depressive Disorder
Interventions
DEVICE
No Results Yet
NCT06142383 | TERMINATED | PHASE2
136 Participants

A Proof of Concept and Dose-finding Study of XXB750 in Patients With Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-12
Completion: 2024-11-01
Conditions
Heart Failure
Interventions
BIOLOGICAL DRUG
NCT06142357 | ACTIVE_NOT_RECRUITING
199 Participants

Secukinumab Drug Survival, Effectiveness and Tolerability in Pediatric Patients With Psoriasis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-29
Completion: 2027-08-31
Conditions
Moderate-to-severe Plaque Psoriasis
Interventions
OTHER
No Results Yet
NCT06141785 | RECRUITING | NA
200 Participants

Early Nutritional Intervention in Patients With Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-06-01
Completion: 2026-03-31
Conditions
Nutritional Intervention Cancer Malnutrition
Interventions
OTHER
No Results Yet
NCT06139406 | ACTIVE_NOT_RECRUITING | PHASE1
70 Participants

A Study of JNJ-87801493 in Combination With T-Cell Engagers in Participants With B-cell Non-Hodgkin Lymphoid (NHLs) Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-06
Completion: 2026-01-30
Conditions
Lymphoma, Non-Hodgkin
Interventions
DRUG
No Results Yet
NCT06132386 | COMPLETED
21 Participants

Analysis of Cellular Kinases and Aging in PBMCs and Colorectal Tissue

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2023-08-07
Completion: 2024-05-20
Conditions
HIV Infections Aging
Interventions
OTHER
NCT06129747 | RECRUITING | PHASE2
55 Participants

Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-11-30
Completion: 2029-08-09
Conditions
Breast Cancer Tumor, Breast
Interventions
RADIATION
No Results Yet
NCT06128564 | RECRUITING | PHASE2
21 Participants

A Gene Delivery Study to Evaluate the Safety and Expression of Delandistrogene Moxeparvovec in Participants Under the Age of Four With Duchenne Muscular Dystrophy (DMD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-11-29
Completion: 2034-01-30
Conditions
Duchenne Muscular Dystrophy
Interventions
GENETIC
No Results Yet
NCT06119581 | RECRUITING | PHASE3
1016 Participants

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-21
Completion: 2026-10-31
Conditions
Carcinoma, Non-Small-Cell Lung Neoplasm Metastasis
Interventions
DRUG
No Results Yet
NCT06113081 | COMPLETED
100 Participants

Real World Experience With Mogamulizumab in the Treatment of Cutaneous T-cell Lymphoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2024-06-06
Completion: 2025-10-10
Conditions
Cutaneous T Cell Lymphoma Cutaneous T-Cell Lymphoma/Mycosis Fungoides Cutaneous T-Cell Lymphoma/Sezary Syndrome
No Results Yet
NCT06107426 | RECRUITING
450 Participants

Real-World Study of ABBV-951 Subcutaneous Infusion to Assess Change in Disease Activity in Adult Participants With Parkinson's Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2024-01-24
Completion: 2029-05-31
Conditions
Parkinson's Disease (PD)
No Results Yet
NCT06105736 | RECRUITING | NA
105 Participants

Regulating Together in Tuberous Sclerosis Complex

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-20
Completion: 2026-12-20
Conditions
TSC Behavioral Symptoms
Interventions
BEHAVIORAL
No Results Yet
NCT06098612 | RECRUITING | EARLY_PHASE1
40 Participants

PET Imaging Evaluation of [11C]SY08

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-05-01
Completion: 2026-11-30
Conditions
Parkinson's Disease Multiple System Atrophy Dementia With Lewy Bodies Healthy Controls
Interventions
DRUG
No Results Yet
NCT06098079 | RECRUITING | PHASE4
8600 Participants

Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contrave®/Mysimba®) on Major Adverse Cardiovascular Events (MACE)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-01-03
Completion: 2029-01-31
Conditions
Obesity
Interventions
DRUG
No Results Yet
NCT06096337 | ACTIVE_NOT_RECRUITING | NA
484 Participants

Pulsed Field Ablation (PFA) vs Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-28
Completion: 2026-02-03
Conditions
Persistent Atrial Fibrillation
Interventions
DEVICE DRUG
No Results Yet
NCT06091787 | COMPLETED | NA
90 Participants

Effect of Ursodeoxycholic Acid Supplementation on Liver Regeneration on Right Lobe Donor Hepatectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-09-01
Completion: 2024-11-30
Conditions
Liver Regeneration Ursodeoxycholic Acid Partial Liver Resection
Interventions
DRUG OTHER
No Results Yet
NCT06080789 | RECRUITING | PHASE2
36 Participants

A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-06-28
Completion: 2026-06-30
Conditions
Acute Pancreatitis
Interventions
DRUG
No Results Yet
NCT06079879 | RECRUITING | PHASE3
340 Participants

A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-31
Completion: 2027-07-30
Conditions
Essential Thrombocythemia
Interventions
DRUG
No Results Yet
NCT06075576 | COMPLETED
23 Participants

Characterization of the Central and Peripheral Wavefront Aberration Profile in Pediatric Myopic Subjects

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2023-11-16
Completion: 2025-08-11
Conditions
Myopia
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06075537 | ENROLLING_BY_INVITATION | PHASE2/PHASE3
99 Participants

An Extension Study of the Long-Term Safety, Tolerability, and Efficacy of Tividenofusp Alfa (DNL310) in Participants With Mucopolysaccharidosis Type II (MPS II) From Study DNLI-E-0002 or Study DNLI-E-0007

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-09-20
Completion: 2027-06-30
Conditions
Mucopolysaccharidosis II
Interventions
DRUG
No Results Yet
NCT06074341 | ACTIVE_NOT_RECRUITING | NA
470 Participants

TeleHealth Resources for IndiVidualizEd Goals (THRIVE) in Alcohol Recovery Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-09-13
Completion: 2028-01-31
Conditions
Alcohol Use Disorder Alcohol Drinking Alcohol-Related Disorders
Interventions
BEHAVIORAL
No Results Yet
NCT06073041 | COMPLETED | NA
20 Participants

Implementing and Evaluating the Integration of Physical Activity Into a Major Health System and Connecting Patients to Physical Activity Programs.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-08-03
Completion: 2023-09-05
Conditions
Chronic Disease Exercise Physical Activity
Interventions
OTHER BEHAVIORAL
No Results Yet
NCT06065462 | RECRUITING | PHASE1/PHASE2
21 Participants

Safety and Efficacy of Targeting PP2A in Ovarian Clear Cell Carcinoma Using Dostarlimab and LB-100

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-11-10
Completion: 2027-10-01
Conditions
Ovarian Clear Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT06052306 | ACTIVE_NOT_RECRUITING | PHASE1
232 Participants
NCT06051617 | RECRUITING | PHASE3
318 Participants

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-09-07
Completion: 2030-08-31
Conditions
Primary Biliary Cholangitis
Interventions
DRUG
No Results Yet
NCT06046170 | ACTIVE_NOT_RECRUITING | NA
60 Participants

Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-02-16
Completion: 2026-04-30
Conditions
Anxiety Autism Spectrum Disorder Separation Anxiety Generalized Anxiety Disorder Social Anxiety Disorder of Childhood
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06044935 | RECRUITING | NA
100 Participants

Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic Rate

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-01-08
Completion: 2026-01-31
Conditions
Overweight Obesity
Interventions
OTHER DIETARY_SUPPLEMENT
No Results Yet
NCT06042725 | RECRUITING | PHASE1
100 Participants

MC210808 Venetoclax in Combination With Lenalidomide and Dexamethasone (Ven-Rd), Daratumumab and Dexamethasone (Ven-Dd), or Daratumumab-Lenalidomide-Dexamethasone (Ven-DRd) for the Treatment of Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-03-04
Completion: 2028-12-01
Conditions
Multiple Myeloma
Interventions
PROCEDURE BIOLOGICAL DRUG OTHER
No Results Yet
NCT06040190 | RECRUITING | PHASE4
150 Participants

Effect of Treatments on Pain and Quality of Life in Individual With Burning Mouth Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-11-01
Completion: 2026-02-01
Conditions
Burning Mouth Syndrome
Interventions
DRUG DIETARY_SUPPLEMENT OTHER RADIATION
No Results Yet
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