Clinical Trials
Showing trials with last updates posted in 2025.
60
Participants
Risk of Reactivation of Occult Hepatitis B in Cancer Patients During Immunotherapy.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2022-06-06
Completion:
2026-05-31
Conditions
Occult Hepatitis B Infection in Cancer Patients
Interventions
OTHER
No Results Yet
30
Participants
Seizure Rescue Medication (RM) as Part of a Comprehensive Epilepsy Self-management Package of Care
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-03-05
Completion:
2026-01-01
Conditions
Epilepsy
Interventions
BEHAVIORAL
DRUG
No Results Yet
378
Participants
ITAKOS - Italian Observation, Multicenter, Prospective Study of Ofatumumab in RRMS Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2024-07-30
Completion:
2026-06-30
Conditions
Multiple Sclerosis, Relapsing-Remitting
Interventions
DRUG
No Results Yet
76
Participants
A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-10-23
Completion:
2026-10-15
Conditions
Primary Myelofibrosis
Post-Essential Thrombocythemia Myelofibrosis
Post-Polycythemia Vera Myelofibrosis
PMF
PPV-MF
PET-MF
Interventions
DRUG
No Results Yet
589
Participants
Identification of Novel High Quality Methylated DNA Markers in Renal Tumors: Whole Methylome Discovery, Tissue Validation, and Feasibility Testing In Blood and Urine, The INQUIRE Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2018-06-27
Completion:
2027-01-31
Conditions
Chromophobe Renal Cell Carcinoma
Clear Cell Papillary Renal Tumor
Clear Cell Renal Cell Carcinoma
Kidney Oncocytoma
Papillary Renal Cell Carcinoma
Urothelial Carcinoma
Interventions
OTHER
No Results Yet
150
Participants
Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-06-14
Completion:
2026-09-30
Conditions
Diabetes Mellitus, Type 1
Interventions
DRUG
No Results Yet
160
Participants
A Study of DM919 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-04-09
Completion:
2026-03-01
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
96
Participants
Pericapsular Nerve Group Block vs Supra Inguinal Fascia Iliaca Compartment Block
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-05-01
Completion:
2025-11-01
Conditions
Pain, Postoperative
Interventions
PROCEDURE
No Results Yet
149
Participants
Effect of Vericiguat on Acute Coronary Syndrome( ACS）Patients With Ejection Fraction <45%
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2024-01-31
Completion:
2025-10-01
Conditions
Acute Coronary Syndrome
Heart Failure With Reduced Ejection Fraction
No Results Yet
140
Participants
A Study to Assess Adverse Events, and How Intravenously (IV) Infused ABBV-969 Moves Through the Bodies of Adult Participants With Metastatic Castration-Resistant Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-03-08
Completion:
2027-05-31
Conditions
Metastatic Castration-Resistant Prostate Cancer
Interventions
DRUG
No Results Yet
180
Participants
Benefits of Individual Physical Activity Intervention on Health-related Quality of Life in Participants With Chronic Lymphocytic Leukemia
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2024-05-27
Completion:
2026-09-30
Conditions
Leukemia, Lymphocytic, Chronic, B-Cell
Interventions
BEHAVIORAL
DRUG
No Results Yet
60
Participants
Erector Spinae Plane Block vs Quadratus Lumborum Block for Laparoscopic Nephrectomy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-03-11
Completion:
2026-03-30
Conditions
Kidney Diseases
Kidney Failure
Interventions
OTHER
No Results Yet
320
Participants
Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-03-15
Completion:
2026-10-31
Conditions
Type 2 Diabetes
Interventions
DRUG
No Results Yet
40
Participants
Clinical and Radiographic Success Rate of Pulpotomy Versus Pulpectomy for Management of Primary Teeth With Deep Caries
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-01-01
Completion:
2026-01-31
Conditions
Deep Caries
Interventions
PROCEDURE
No Results Yet
0
Participants
Examining the Effects of Morning and Evening Exercise on Glucose Regulation in Adults With Prediabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-02-01
Completion:
2026-06-30
Conditions
PreDiabetes
Obesity
Inactivity/Low Levels of Exercise
Interventions
BEHAVIORAL
No Results Yet
40
Participants
PediRISE Feasibility
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-05-15
Completion:
2025-12-31
Conditions
Pediatric Cancer
Financial Stress
Financial Hardship
Disparities
Interventions
BEHAVIORAL
No Results Yet
42
Participants
Differences in Speed of Recovery From Anesthesia for Intraoral Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-04-10
Completion:
2025-11-05
Conditions
Intraoral Tumor
Interventions
DRUG
No Results Yet
200
Participants
Comparing Enhanced Cognitive-behavior Therapy and Family-based Treatment for Adolescents With an Eating Disorder
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-03-07
Completion:
2028-12-31
Conditions
Feeding and Eating Disorders
Interventions
BEHAVIORAL
No Results Yet
42
Participants
Clinical and Histological Study of a Novel Dermal Substitute
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2024-01-15
Completion:
2026-06-01
Conditions
Skin Transplantation
Interventions
OTHER
No Results Yet
10
Participants
pCCLCHIM-p47 (Lentiviral Vector Transduced CD34 Plus Cells) in Patients With p47 Autosomal Recessive Chronic Granulomatous Disease (AR-CGD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-06-25
Completion:
2027-03-31
Conditions
p47
Autosomal Recessive
Chronic Granulomatous Disease
Interventions
BIOLOGICAL
No Results Yet
2
Participants
Evaluating Spinal Cord Stimulation for Stiff Person Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-11-01
Completion:
2025-08-21
Conditions
Stiff-Person Syndrome
Interventions
DEVICE
No Results Yet
80
Participants
Study on Allopregnanolone and Depression in Women Across the Menopause Transition
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-05-14
Completion:
2027-07-31
Conditions
Depression
Interventions
DIETARY_SUPPLEMENT
OTHER
No Results Yet
132
Participants
Long-term Safety and Tolerability of HRS-5965 in Patients With Paroxysmal Nocturnal Hemoglobinuria
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-02-06
Completion:
2027-12-31
Conditions
Paroxysmal Nocturnal Hemoglobinuria
Interventions
DRUG
No Results Yet
250
Participants
QTX3034 in Patients With KRAS G12D Mutation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-02-05
Completion:
2027-04-01
Conditions
Solid Tumors
Interventions
DRUG
COMBINATION_PRODUCT
No Results Yet
210
Participants
A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-07-18
Completion:
2026-11-30
Conditions
Inflammatory Bowel Diseases
Crohn's Disease
Interventions
DRUG
No Results Yet
956
Participants
Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-01-24
Completion:
2030-12-31
Conditions
Metastatic Urothelial Cancer
Interventions
DRUG
No Results Yet
60
Participants
CIH Stepped Care for Co-occurring Chronic Pain and PTSD
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-01-02
Completion:
2027-05-31
Conditions
Chronic Pain
Posttraumatic Stress Disorder
Interventions
BEHAVIORAL
No Results Yet
3
Participants
Evaluate the Safety and Potential Efficacy of Human Wharton's Jelly-derived Mesenchymal Stem Cells With Charcot-Marie-Tooth Disease Type 1E
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-05-23
Completion:
2024-10-28
Conditions
Charcot-Marie-Tooth Disease, Type 1
Interventions
BIOLOGICAL
No Results Yet
57
Participants
A Phase 1/2 Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-001 in Glanzmann Thrombasthenia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-12-13
Completion:
2027-08-31
Conditions
Glanzmann Thrombasthenia
Interventions
DRUG
No Results Yet
97
Participants
Effect of Irrigation-Activation Techniques on Healing in Large Periapical Lesions
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-11-01
Completion:
2023-02-27
Conditions
Effect of Irrigation Activation on Periapical Healing
Interventions
PROCEDURE
66
Participants
Efficacy of Whole-body Electromyostimulation (WB-EMS) Training in Participants With Pre-diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-01-23
Completion:
2025-12-17
Conditions
Pre-diabetes
Interventions
OTHER
No Results Yet
30
Participants
Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-11-01
Completion:
2026-09-30
Conditions
Sickle Cell Disease
Vaso-occlusive Pain Episode in Sickle Cell Disease
Acute Pain
Interventions
DEVICE
OTHER
No Results Yet
200
Participants
POLARx Post Approval Study (POLARx PAS)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-06-28
Completion:
2026-05-31
Conditions
Paroxysmal Atrial Fibrillation
Interventions
DEVICE
No Results Yet
380
Participants
Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-05-19
Completion:
2027-12-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
36
Participants
Cognitive Effects of tDCS and tRNS in Schizophrenia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-01-01
Completion:
2023-11-01
Conditions
Schizophrenia
Cognitive Impairment
Interventions
DEVICE
No Results Yet
220
Participants
A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-12-20
Completion:
2026-12-04
Conditions
Myeloproliferative Disorders
Essential Thrombocythemia
Neoplasms
Myelofibrosis
Interventions
DRUG
No Results Yet
60
Participants
The Impact of Expressive Emotional Writing on Facilitating Grief Resolution in Adults With Spinal Cord Injury
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-05-03
Completion:
2026-12-31
Conditions
Spinal Cord Injuries
Transverse Myelitis
Interventions
BEHAVIORAL
No Results Yet
90
Participants
Improving Antibiotic Use for ARIs in Urgent Care Clinics
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-01-01
Completion:
2025-06-30
Conditions
Antibacterial Agents
Ambulatory Care
Interventions
BEHAVIORAL
No Results Yet
144
Participants
RESEARCH EVALUATING VAGAL EXCITATION AND ANATOMICAL LINKS
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-12-15
Completion:
2026-08-01
Conditions
Epilepsy
Depressive Disorder
Interventions
DEVICE
No Results Yet
136
Participants
A Proof of Concept and Dose-finding Study of XXB750 in Patients With Heart Failure
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-12-12
Completion:
2024-11-01
Conditions
Heart Failure
Interventions
BIOLOGICAL
DRUG
Showing 40 trials per page