Clinical Trials

Showing trials with last updates posted in 2025.

NCT06292000 | WITHDRAWN | NA
0 Participants

Examining the Effects of Morning and Evening Exercise on Glucose Regulation in Adults With Prediabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-02-01
Completion: 2026-06-30
Conditions
PreDiabetes Obesity Inactivity/Low Levels of Exercise
Interventions
BEHAVIORAL
No Results Yet
NCT06283251 | RECRUITING | NA
40 Participants

PediRISE Feasibility

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-05-15
Completion: 2025-12-31
Conditions
Pediatric Cancer Financial Stress Financial Hardship Disparities
Interventions
BEHAVIORAL
No Results Yet
NCT06275087 | RECRUITING | NA
42 Participants

Differences in Speed of Recovery From Anesthesia for Intraoral Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-04-10
Completion: 2025-11-05
Conditions
Intraoral Tumor
Interventions
DRUG
No Results Yet
NCT06256380 | RECRUITING | NA
200 Participants

Comparing Enhanced Cognitive-behavior Therapy and Family-based Treatment for Adolescents With an Eating Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-03-07
Completion: 2028-12-31
Conditions
Feeding and Eating Disorders
Interventions
BEHAVIORAL
No Results Yet
NCT06255990 | RECRUITING
42 Participants

Clinical and Histological Study of a Novel Dermal Substitute

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2024-01-15
Completion: 2026-06-01
Conditions
Skin Transplantation
Interventions
OTHER
No Results Yet
NCT06253507 | ENROLLING_BY_INVITATION | PHASE1/PHASE2
10 Participants

pCCLCHIM-p47 (Lentiviral Vector Transduced CD34 Plus Cells) in Patients With p47 Autosomal Recessive Chronic Granulomatous Disease (AR-CGD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-06-25
Completion: 2027-03-31
Conditions
p47 Autosomal Recessive Chronic Granulomatous Disease
Interventions
BIOLOGICAL
No Results Yet
NCT06242678 | COMPLETED | NA
2 Participants

Evaluating Spinal Cord Stimulation for Stiff Person Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-11-01
Completion: 2025-08-21
Conditions
Stiff-Person Syndrome
Interventions
DEVICE
No Results Yet
NCT06238700 | RECRUITING | NA
80 Participants

Study on Allopregnanolone and Depression in Women Across the Menopause Transition

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-05-14
Completion: 2027-07-31
Conditions
Depression
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT06238544 | ACTIVE_NOT_RECRUITING | PHASE2
132 Participants

Long-term Safety and Tolerability of HRS-5965 in Patients With Paroxysmal Nocturnal Hemoglobinuria

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-02-06
Completion: 2027-12-31
Conditions
Paroxysmal Nocturnal Hemoglobinuria
Interventions
DRUG
No Results Yet
NCT06227377 | RECRUITING | PHASE1
250 Participants

QTX3034 in Patients With KRAS G12D Mutation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-02-05
Completion: 2027-04-01
Conditions
Solid Tumors
Interventions
DRUG COMBINATION_PRODUCT
No Results Yet
NCT06226883 | RECRUITING | PHASE2
210 Participants

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-07-18
Completion: 2026-11-30
Conditions
Inflammatory Bowel Diseases Crohn's Disease
Interventions
DRUG
No Results Yet
NCT06225596 | RECRUITING | PHASE2/PHASE3
956 Participants

Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-01-24
Completion: 2030-12-31
Conditions
Metastatic Urothelial Cancer
Interventions
DRUG
No Results Yet
NCT06219408 | RECRUITING | NA
60 Participants

CIH Stepped Care for Co-occurring Chronic Pain and PTSD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-01-02
Completion: 2027-05-31
Conditions
Chronic Pain Posttraumatic Stress Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT06218134 | COMPLETED | NA
3 Participants

Evaluate the Safety and Potential Efficacy of Human Wharton's Jelly-derived Mesenchymal Stem Cells With Charcot-Marie-Tooth Disease Type 1E

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-05-23
Completion: 2024-10-28
Conditions
Charcot-Marie-Tooth Disease, Type 1
Interventions
BIOLOGICAL
No Results Yet
NCT06211634 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
57 Participants

A Phase 1/2 Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-001 in Glanzmann Thrombasthenia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-12-13
Completion: 2027-08-31
Conditions
Glanzmann Thrombasthenia
Interventions
DRUG
No Results Yet
NCT06204887 | COMPLETED | NA
97 Participants

Effect of Irrigation-Activation Techniques on Healing in Large Periapical Lesions

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-11-01
Completion: 2023-02-27
Conditions
Effect of Irrigation Activation on Periapical Healing
Interventions
PROCEDURE
NCT06189391 | RECRUITING | PHASE1
100 Participants

A Study to Evaluate MK-1045 (CN201) in Participants With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (MK-1045-001/CN201-101)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-03-16
Completion: 2027-03-31
Conditions
Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Interventions
DRUG
No Results Yet
NCT06188481 | COMPLETED | NA
66 Participants

Efficacy of Whole-body Electromyostimulation (WB-EMS) Training in Participants With Pre-diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-01-23
Completion: 2025-12-17
Conditions
Pre-diabetes
Interventions
OTHER
No Results Yet
NCT06184126 | RECRUITING | NA
30 Participants

Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-11-01
Completion: 2026-09-30
Conditions
Sickle Cell Disease Vaso-occlusive Pain Episode in Sickle Cell Disease Acute Pain
Interventions
DEVICE OTHER
No Results Yet
NCT06170788 | RECRUITING | PHASE3
614 Participants

Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-15
Completion: 2028-01-25
Conditions
Non-small Cell Lung Cancer (NSCLC)
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06170606 | RECRUITING | NA
200 Participants

POLARx Post Approval Study (POLARx PAS)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-06-28
Completion: 2026-05-31
Conditions
Paroxysmal Atrial Fibrillation
Interventions
DEVICE
No Results Yet
NCT06158841 | RECRUITING | PHASE3
380 Participants

Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-05-19
Completion: 2027-12-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06155786 | COMPLETED | NA
36 Participants

Cognitive Effects of tDCS and tRNS in Schizophrenia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-01-01
Completion: 2023-11-01
Conditions
Schizophrenia Cognitive Impairment
Interventions
DEVICE
No Results Yet
NCT06150157 | RECRUITING | PHASE1
220 Participants

A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-20
Completion: 2026-12-04
Conditions
Myeloproliferative Disorders Essential Thrombocythemia Neoplasms Myelofibrosis
Interventions
DRUG
No Results Yet
NCT06147258 | RECRUITING | NA
60 Participants

The Impact of Expressive Emotional Writing on Facilitating Grief Resolution in Adults With Spinal Cord Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-05-03
Completion: 2026-12-31
Conditions
Spinal Cord Injuries Transverse Myelitis
Interventions
BEHAVIORAL
No Results Yet
NCT06144242 | ACTIVE_NOT_RECRUITING | NA
90 Participants

Improving Antibiotic Use for ARIs in Urgent Care Clinics

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-01-01
Completion: 2025-06-30
Conditions
Antibacterial Agents Ambulatory Care
Interventions
BEHAVIORAL
No Results Yet
NCT06143293 | RECRUITING | NA
144 Participants

RESEARCH EVALUATING VAGAL EXCITATION AND ANATOMICAL LINKS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-15
Completion: 2026-08-01
Conditions
Epilepsy Depressive Disorder
Interventions
DEVICE
No Results Yet
NCT06142383 | TERMINATED | PHASE2
136 Participants

A Proof of Concept and Dose-finding Study of XXB750 in Patients With Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-12
Completion: 2024-11-01
Conditions
Heart Failure
Interventions
BIOLOGICAL DRUG
NCT06142357 | ACTIVE_NOT_RECRUITING
199 Participants

Secukinumab Drug Survival, Effectiveness and Tolerability in Pediatric Patients With Psoriasis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-29
Completion: 2027-08-31
Conditions
Moderate-to-severe Plaque Psoriasis
Interventions
OTHER
No Results Yet
NCT06141785 | RECRUITING | NA
200 Participants

Early Nutritional Intervention in Patients With Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-06-01
Completion: 2026-03-31
Conditions
Nutritional Intervention Cancer Malnutrition
Interventions
OTHER
No Results Yet
NCT06139406 | ACTIVE_NOT_RECRUITING | PHASE1
70 Participants

A Study of JNJ-87801493 in Combination With T-Cell Engagers in Participants With B-cell Non-Hodgkin Lymphoid (NHLs) Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-06
Completion: 2026-01-30
Conditions
Lymphoma, Non-Hodgkin
Interventions
DRUG
No Results Yet
NCT06132958 | ACTIVE_NOT_RECRUITING | PHASE3
710 Participants

Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post Immunotherapy Endometrial Cancer (MK-2870-005)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-06
Completion: 2028-01-10
Conditions
Endometrial Cancer
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06132386 | COMPLETED
21 Participants

Analysis of Cellular Kinases and Aging in PBMCs and Colorectal Tissue

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2023-08-07
Completion: 2024-05-20
Conditions
HIV Infections Aging
Interventions
OTHER
NCT06129747 | RECRUITING | PHASE2
55 Participants

Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-11-30
Completion: 2029-08-09
Conditions
Breast Cancer Tumor, Breast
Interventions
RADIATION
No Results Yet
NCT06128564 | RECRUITING | PHASE2
21 Participants

A Gene Delivery Study to Evaluate the Safety and Expression of Delandistrogene Moxeparvovec in Participants Under the Age of Four With Duchenne Muscular Dystrophy (DMD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-11-29
Completion: 2034-01-30
Conditions
Duchenne Muscular Dystrophy
Interventions
GENETIC
No Results Yet
NCT06119581 | RECRUITING | PHASE3
1016 Participants

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-21
Completion: 2026-10-31
Conditions
Carcinoma, Non-Small-Cell Lung Neoplasm Metastasis
Interventions
DRUG
No Results Yet
NCT06113081 | COMPLETED
100 Participants

Real World Experience With Mogamulizumab in the Treatment of Cutaneous T-cell Lymphoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2024-06-06
Completion: 2025-10-10
Conditions
Cutaneous T Cell Lymphoma Cutaneous T-Cell Lymphoma/Mycosis Fungoides Cutaneous T-Cell Lymphoma/Sezary Syndrome
No Results Yet
NCT06107426 | RECRUITING
450 Participants

Real-World Study of ABBV-951 Subcutaneous Infusion to Assess Change in Disease Activity in Adult Participants With Parkinson's Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2024-01-24
Completion: 2029-05-31
Conditions
Parkinson's Disease (PD)
No Results Yet
NCT06105736 | RECRUITING | NA
105 Participants

Regulating Together in Tuberous Sclerosis Complex

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-20
Completion: 2026-12-20
Conditions
TSC Behavioral Symptoms
Interventions
BEHAVIORAL
No Results Yet
NCT06098612 | RECRUITING | EARLY_PHASE1
40 Participants

PET Imaging Evaluation of [11C]SY08

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-05-01
Completion: 2026-11-30
Conditions
Parkinson's Disease Multiple System Atrophy Dementia With Lewy Bodies Healthy Controls
Interventions
DRUG
No Results Yet
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