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Clinical Trials

Showing trials with last updates posted in 2025.

NCT05992480 | RECRUITING | PHASE4
40 Participants

REVIVE (Response to the Ebola Virus Vaccine)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-12-01
Completion: 2026-05-31
Conditions
Ebola Virus Disease
Interventions
BIOLOGICAL
No Results Yet
NCT05981547 | ACTIVE_NOT_RECRUITING
400 Participants

Patterns and Glycaemic Endpoints for Diagnosing Gestational Diabetes

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2023-11-22
Completion: 2026-06-21
Conditions
Gestational Diabetes
Interventions
DEVICE
No Results Yet
NCT05975073 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
53 Participants

A Phase 1/2 Study of AMG 193 in Combination With IDE397 in Participants With Advanced Methylthioadenosine Phosphorylase (MTAP)-Null Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-08-01
Completion: 2026-04-01
Conditions
MTAP-null Non-Small-Cell Lung Cancer MTAP-null Solid Tumors
Interventions
DRUG
No Results Yet
NCT05974631 | RECRUITING | NA
125 Participants

Evaluating Treatments for Suicidal Veterans With PTSD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-07-08
Completion: 2027-04-30
Conditions
Self-directed Violence Post-traumatic Stress Disorder (PTSD)
Interventions
BEHAVIORAL
No Results Yet
NCT05972694 | ACTIVE_NOT_RECRUITING | NA
20 Participants

Effect of Grapes in Inflammatory Bowel Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-16
Completion: 2025-08-01
Conditions
Crohn Disease
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT05962229 | RECRUITING | PHASE1
18 Participants

Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-06
Completion: 2026-09-30
Conditions
Nicotine Dependence Nicotine Vaping
Interventions
DRUG
No Results Yet
NCT05960773 | SUSPENDED | PHASE2
9 Participants

Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-01-31
Completion: 2026-12-01
Conditions
Mesothelioma Malignant Mesothelioma (MM) Early-stage Mesothelioma Subclinical Mesothelioma BRCA1-Associated Protein-1 (BAP1) Mutations Early-stage BAP1-associated Malignancies
Interventions
DRUG
No Results Yet
NCT05943535 | RECRUITING | PHASE3
698 Participants

Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-10-30
Completion: 2027-11-30
Conditions
Progressive Pulmonary Fibrosis Interstitial Lung Disease
Interventions
DRUG DEVICE
No Results Yet
NCT05941286 | COMPLETED | NA
533 Participants

Effect of Continuous Glucose Monitoring System Alerts on Diabetes Management in the Hospital

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-04-18
Completion: 2024-12-16
Conditions
Diabetes Mellitus
Interventions
DEVICE
No Results Yet
NCT05928806 | RECRUITING | PHASE2
120 Participants

Advanced Renal Cell Cancer Combination ImmunoThErapy Clinical Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-09-25
Completion: 2026-01-10
Conditions
Advanced Renal Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT05921994 | ACTIVE_NOT_RECRUITING
425 Participants

Long Term Observational Study to Collect in a Real-world populatIon Data on the Treatment Pattern of secukinumAb in Adult Patients With Moderate to Severe Hidradenitis Suppurativa.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2023-08-10
Completion: 2027-03-31
Conditions
Hidradenitis Suppurativa
Interventions
OTHER
No Results Yet
NCT05916274 | COMPLETED | NA
40 Participants

Exploration of the Activity of DNA Located Outside of Cellular Nucleus to Amplify Inflammation in Inflammatory Bowel Disease in Children Through Biological Pathway Cyclic GMP-AMP Synthase (cGAS) - Stimulator of Interferon Genes (STING)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-05-31
Completion: 2024-02-29
Conditions
Crohn Disease Ulcerative Colitis Inflammatory Bowel Diseases
Interventions
BIOLOGICAL PROCEDURE
No Results Yet
NCT05916170 | COMPLETED | NA
977 Participants

A Study of Hookah Café Customers in the Atlanta Area

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-06-01
Completion: 2024-11-21
Conditions
Waterpipe Tobacco Smoking
Interventions
BEHAVIORAL
Results Available
NCT05915468 | COMPLETED
306 Participants

Large De-NOVo Coronary artEry Disease Treated With Sirolimus Drug Eluting Balloon (LOVE DEB)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2023-07-12
Completion: 2025-12-11
Conditions
Coronary Artery Disease
No Results Yet
NCT05913882 | RECRUITING | NA
34 Participants

Combined Respiratory Training in Persons With ALS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-08-22
Completion: 2026-09-30
Conditions
ALS Respiratory Insufficiency Dysphagia
Interventions
DEVICE
No Results Yet
NCT05910606 | ACTIVE_NOT_RECRUITING | NA
92 Participants

Strong Foundations 2.0: A Digitally Delivered Fall Prevention Program.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-09-01
Completion: 2026-07-16
Conditions
Fall Prevention Bone Health Balance
Interventions
BEHAVIORAL
No Results Yet
NCT05905302 | COMPLETED | NA
15 Participants

The Impact of Exercise on Subthalamic Nucleus Neural Activity in Parkinson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-08-15
Completion: 2024-09-20
Conditions
Parkinson Disease Deep Brain Stimulation
Interventions
OTHER
Results Available
NCT05900388 | NOT_YET_RECRUITING
850 Participants

A Study to Observe the Pattern of Use and Safety of Rivaroxaban in Children Under 2 Years Old With Venous Thromboembolism (VTE)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2026-09-01
Completion: 2029-06-30
Conditions
Venous Thromboembolism Children Under 2 Years
Interventions
DRUG
No Results Yet
NCT05891119 | COMPLETED | EARLY_PHASE1
21 Participants

Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-06-03
Completion: 2024-08-28
Conditions
Atopic Dermatitis
Interventions
DIETARY_SUPPLEMENT DRUG
No Results Yet
NCT05880251 | COMPLETED | NA
20 Participants

Operant Conditioning of Sensory Brain Responses to Reduce Phantom Limb Pain in People With Limb Amputation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-07-01
Completion: 2025-07-01
Conditions
Phantom Limb Pain After Amputation Lower Limb Amputation Upper Limb Amputation Phantom Pain Chronic Pain
Interventions
BEHAVIORAL
No Results Yet
NCT05873192 | RECRUITING | PHASE2
30 Participants

Presurgical Phase II Study of Talazoparib in Combination With Enzalutamide in Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-06-03
Completion: 2026-12-31
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT05862285 | RECRUITING | PHASE3
100 Participants

A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-06-01
Completion: 2033-03-01
Conditions
Cancer
Interventions
DRUG
No Results Yet
NCT05856448 | ACTIVE_NOT_RECRUITING | PHASE2
186 Participants

A Study Evaluating the Effects of GLPG3667 Administered as Oral Treatment in Adult Participants With Active Systemic Lupus Erythematosus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-06-28
Completion: 2025-10-08
Conditions
Systemic Lupus Erythematosus
Interventions
DRUG
No Results Yet
NCT05854485 | COMPLETED | NA
24 Participants

Robot-Aided Assessment and Rehabilitation of Upper Extremity Function After Stroke

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-09-06
Completion: 2025-05-30
Conditions
Stroke
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT05835310 | RECRUITING | PHASE3
100 Participants

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-03-14
Completion: 2028-10-05
Conditions
Systemic Lupus Erythematosus
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT05830760 | WITHDRAWN | NA
0 Participants

Expression of Sodium-glucose Co-transporter 2 in Human Heart

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-06-30
Completion: 2025-10-31
Conditions
Aortic Valve Stenosis
Interventions
BIOLOGICAL
No Results Yet
NCT05828589 | ACTIVE_NOT_RECRUITING | PHASE1
112 Participants

A Study of BGB-21447, a Bcl-2 Inhibitor, in Mature B-Cell Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-06-20
Completion: 2027-04-30
Conditions
Relapsed Non-Hodgkin Lymphoma Refractory Non-Hodgkin Lymphoma Relapsed Chronic Lymphocytic Leukemia Refractory Chronic Lymphocytic Leukemia Relapsed Follicular Lymphoma Relapsed Marginal Zone Lymphoma Relapse Diffuse Large B Cell Lymphoma Relapsed Small Lymphocytic Lymphoma Refractory Follicular Lymphoma Refractory Marginal Zone Lymphoma Refractory Small Lymphocytic Lymphoma Richter Transformation Refractory Diffuse Large B-cell Lymphoma Transformed Non-Hodgkin Lymphoma
Interventions
DRUG
No Results Yet
NCT05827926 | COMPLETED | PHASE1/PHASE2
1758 Participants

A Study of mRNA-based Influenza and SARS-CoV-2 (COVID-19) Multi-component Vaccines in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-04-14
Completion: 2024-12-03
Conditions
SARS-CoV-2 Influenza
Interventions
BIOLOGICAL
Results Available
NCT05827016 | RECRUITING | PHASE3
1216 Participants

A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-06-22
Completion: 2029-03-15
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05803720 | COMPLETED | NA
59 Participants

HIV Provider Intervention to Address Intersectional Stigma and Medical Mistrust

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-04-01
Completion: 2024-03-31
Conditions
Stigma, Social
Interventions
BEHAVIORAL
Results Available
NCT05800665 | RECRUITING | PHASE1
210 Participants

A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-05-02
Completion: 2027-06-30
Conditions
Advanced Prostate Cancer Metastatic Prostate Cancer
Interventions
DRUG
No Results Yet
NCT05783609 | RECRUITING | PHASE2
100 Participants

Epcoritamab and Rituximab for First-line Follicular Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-06-21
Completion: 2028-02-29
Conditions
Follicular Lymphoma Low Grade Non-Hodgkin's Lymphoma, Adult
Interventions
DRUG
No Results Yet
NCT05763901 | COMPLETED | NA
151 Participants

IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and Dysmorphisms

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-04-01
Completion: 2024-05-16
Conditions
Genu Varum Genu Valgus Flat Feet Cavus Foot Scoliosis Idiopathic Varus; Talipes Valgus, Talipes Laxity of Ligament Hyperlordosis Hyperkyphosis Angular Limb Deformity
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05759143 | RECRUITING | NA
40 Participants

Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-05-01
Completion: 2026-03-30
Conditions
Genetic Predisposition to Disease Genetic Predisposition
Interventions
BEHAVIORAL
No Results Yet
NCT05746845 | COMPLETED
100 Participants

Implication of 5-HT7 Receptor in Inflammatory Mechanisms in Multiple Sclerosis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2023-03-06
Completion: 2024-07-01
Conditions
Healthy Multiple Sclerosis
Interventions
BIOLOGICAL
No Results Yet
NCT05742802 | ACTIVE_NOT_RECRUITING | PHASE3
1710 Participants

Long-term Efficacy and Safety of Tozorakimab in Participants With Chronic Obstructive Pulmonary Disease With a History of Exacerbations (PROSPERO).

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-03-06
Completion: 2026-02-26
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT05739383 | ACTIVE_NOT_RECRUITING | PHASE3
14082 Participants

A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-03-09
Completion: 2029-04-16
Conditions
Primary Prevention of Atherosclerotic Cardiovascular Disease
Interventions
DRUG
No Results Yet
NCT05736497 | COMPLETED | NA
164 Participants

Care Plans for Cancer Predisposition

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-08-25
Completion: 2025-06-10
Conditions
Genetic Predisposition
Interventions
OTHER
No Results Yet
NCT05723198 | RECRUITING | PHASE3
595 Participants

A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-02-27
Completion: 2027-09-30
Conditions
Areata Alopecia Alopecia Hypotrichosis Hair Diseases Skin Diseases Pathological Conditions, Anatomical
Interventions
DRUG
No Results Yet
NCT05707377 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
178 Participants

A Study to Examine the Efficacy and Safety of Zanubrutinib Given to Adults With Primary Membranous Nephropathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2023-04-17
Completion: 2027-10-31
Conditions
Primary Membranous Nephropathy
Interventions
DRUG
No Results Yet
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