Expression of Sodium-glucose Co-transporter 2 in Human Heart
NCT ID: NCT05830760
Last Updated: 2025-12-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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WITHDRAWN
NA
INTERVENTIONAL
2023-06-30
2025-10-31
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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NON_RANDOMIZED
PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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patients with aortic valve stenosis with heart failure
Myocardium biopsy
The expression of SGLT2 on small myocardium specimens harvested during aortic valve replacement operation in patients with aortic stenosis
patients with aortic valve stenosis without heart failure
Myocardium biopsy
The expression of SGLT2 on small myocardium specimens harvested during aortic valve replacement operation in patients with aortic stenosis
Interventions
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Myocardium biopsy
The expression of SGLT2 on small myocardium specimens harvested during aortic valve replacement operation in patients with aortic stenosis
Eligibility Criteria
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Inclusion Criteria
* Patient with surgical aortic valve stenosis, with or without heart failure, in two equal-sized groups (40 subjects in each group)
* Subjects affiliated with a social security health insurance plan
* Subject able to understand the objectives and risks of the research and to give dated and signed informed consent
Exclusion Criteria
* Severe coronary pathology associated with aortic stenosis
* Impossible to give the subject informed information (subject in emergency situation, difficulties in understanding the subject, ...)
* Subject under legal protection
* Subject under guardianship or curatorship
* Pregnancy and/or breastfeeding
18 Years
ALL
No
Sponsors
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University Hospital, Strasbourg, France
OTHER
Responsible Party
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Locations
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Hôpitaux Universitaires de Strasbourg
Strasbourg, , France
Countries
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Other Identifiers
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8774
Identifier Type: -
Identifier Source: org_study_id