In-depth Characterization of Atriogenic Secondary Tricuspid Regurgitation Due to Atrial Fibrillation
NCT ID: NCT05749107
Last Updated: 2024-03-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
1050 participants
OBSERVATIONAL
2022-12-02
2025-11-02
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Atrial secondary tricuspid regurgitation
Patients with persistent/permanent atrial fibrillation and any degree of isolated tricuspid regurgitation
Echocardiography
Identify AF patients at risk of developing moderate/severe STR and those who will benefit from restoring the normal sinus rhythm
Proteomic analyses
To identify the mechanisms leading to moderate/severe STR during AF.
Interventions
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Echocardiography
Identify AF patients at risk of developing moderate/severe STR and those who will benefit from restoring the normal sinus rhythm
Proteomic analyses
To identify the mechanisms leading to moderate/severe STR during AF.
Eligibility Criteria
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Inclusion Criteria
* persistent/permanent atrial fibrillation
* good acoustic apical window
* left ventricular ejection fraction \> 50%
* pulmonary artery systolic pressure\< 50 mm Hg
* no more than mild mitral or aortic valve disease
* ability to attend clinical and echocardiographic follow-ups
* signature of the study informed consent
Exclusion Criteria
* implanted pace-maker or ICD
* previous heart valve surgery or transcatheter treatment
* previous heart transplant
* organic tricuspid regurgitation
18 Years
ALL
No
Sponsors
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Ministry of Health, Italy
OTHER_GOV
Istituto Auxologico Italiano
OTHER
Responsible Party
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Locations
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Istituto Auxologico Italiano, IRCCS
Milan, Select A State, Italy
IRCCS Ospedale San Raffaele
Milan, , Italy
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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09M202
Identifier Type: -
Identifier Source: org_study_id
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