Interest of Pulse Wave Velocity Measurement as a Predictor of Severity of Aortic Stenosis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2017-07-03

Study Completion Date

2023-06-20

Brief Summary

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Aortic valve pathology is the third most common cardiovascular disease after coronary artery disease and hypertension, which is responsible for severe morbidity and mortality in elderly patients and requires surgical treatment in its most severe form of progression. The purpose of this study is to find a link between arterial stiffness and degenerative aortic stenosis. If this link is established, arterial stiffness may become a medical therapeutic target in order to delay the evolution of the disease.

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Detailed Description

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Conditions

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Pulse Wave Aortic Stenosis

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Control group of 150 heart disease-free individuals

Group Type OTHER

Control group without heart disease

Intervention Type OTHER

Control group without heart disease

Patients with aortic sclerosis

Group Type OTHER

Study the relationship between the arterial rigidity of large vessels and the presence and severity of degenerative aortic constriction

Intervention Type OTHER

Study the relationship between the arterial rigidity of large vessels and the presence and severity of degenerative aortic constriction

Patients with moderate aortic stenting (RA)

Group Type OTHER

Study the relationship between the arterial rigidity of large vessels and the presence and severity of degenerative aortic constriction

Intervention Type OTHER

Study the relationship between the arterial rigidity of large vessels and the presence and severity of degenerative aortic constriction

Patients with Serious Aortic Retention

Group Type OTHER

Study the relationship between the arterial rigidity of large vessels and the presence and severity of degenerative aortic constriction

Intervention Type OTHER

Study the relationship between the arterial rigidity of large vessels and the presence and severity of degenerative aortic constriction

Interventions

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Study the relationship between the arterial rigidity of large vessels and the presence and severity of degenerative aortic constriction

Intervention Type OTHER

Control group without heart disease

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients over 18 years of age, without legal protection (guardianship or curatorship),
* Stable hemodynamic status.
* Affiliation to a social security scheme

Exclusion Criteria

* Hemodynamically unstable patients: Systolic PA \<10 cmHg, rapid peripheral pulse and spinning, mottling, obnubilation, oliguria, sweating, coma
* History of significant valvulopathy other than an aortic stenosis,
* Pregnancy.
* Patient under tutelage or curatelle or deprived of public right.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No