Role of Aortic Valve Composition in Pathophysiology and Diagnosis of Aortic Stenosis
NCT ID: NCT06136689
Last Updated: 2023-11-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
55 participants
OBSERVATIONAL
2022-01-01
2025-05-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Severe Aortic Stenosis - High Flow, High Gradient
patients undergoing surgical aortic valve replacement for severe AS
No interventions assigned to this group
Severe Aortic Stenosis - classical Low Flow, Low Gradient
patients undergoing surgical aortic valve replacement for severe AS
No interventions assigned to this group
Severe Aortic Stenosis - paradoxical Low Flow, Low Gradient
patients undergoing surgical aortic valve replacement for severe AS
No interventions assigned to this group
Moderate Aortic Stenosis
patients undergoing aortic root replacement (Bentall procedure)
No interventions assigned to this group
Heart Transplant
patients undergoing orthotopic heart transplant for any reason
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* pre-surgical computed tomography angiography
* informed consent
18 Years
ALL
No
Sponsors
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Polish Cardiac Society
OTHER
Medical University of Warsaw
OTHER
Responsible Party
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Kajetan Grodecki
Principal Investigator
Principal Investigators
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Zenon Huczek, MD,PhD
Role: STUDY_DIRECTOR
Medical University of Warsaw
Locations
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Medical University of Silesia
Katowice, , Poland
Poznan University of Medical Sciences
Poznan, , Poland
Countries
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Central Contacts
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Facility Contacts
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Radoslaw Gocol, MD, PhD
Role: primary
Anna Olasinska-Wisniewska, MD, PhD
Role: primary
Tomasz Urbanowicz, MD, PhD
Role: backup
References
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Grodecki K, Tamarappoo BK, Huczek Z, Jedrzejczyk S, Cadet S, Kwiecinski J, Rymuza B, Parma R, Olasinska-Wisniewska A, Fijalkowska J, Protasiewicz M, Walczak A, Nowak A, Gocol R, Slomka PJ, Reczuch K, Jagielak D, Grygier M, Wojakowski W, Filipiak KJ, Dey D. Non-calcific aortic tissue quantified from computed tomography angiography improves diagnosis and prognostication of patients referred for transcatheter aortic valve implantation. Eur Heart J Cardiovasc Imaging. 2021 May 10;22(6):626-635. doi: 10.1093/ehjci/jeaa304.
Other Identifiers
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1WR/DAR15
Identifier Type: -
Identifier Source: org_study_id
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