Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
28 participants
OBSERVATIONAL
2016-05-31
2017-11-30
Brief Summary
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Patients with moderate aortic stenosis are enrolled and underwent baseline evaluation including 18F-sodium fluoride PET/CT. After 1 year, all the participants underwent follow-up echocardiography. The study design is an observational trial. Primary endpoint was a change in mean pressure gradient along the aortic valve as assessed by echocardiography at 1 year. Secondary endpoints include changes in aortic valve area, and symptom occurrence.
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Detailed Description
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Patients with moderate aortic stenosis - diagnosed by echocardiography - will be enrolled. Enrolled participants will undergo baseline 18F-NaF PET/CT within 6 weeks of baseline echocardiography and followed up for 1 year. After 1 year, all the participants are required to evaluate the aortic stenosis progression by performing echocardiography.
The objective of the study is to test whether baseline 18F-NaF uptake activity predict AS progression.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Interventions
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Imaging test: 18F-NaF PET/CT
18F-NaF PET/CT as an imaging test
Eligibility Criteria
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Inclusion Criteria
* moderate aortic stenosis
Exclusion Criteria
* pregnant women
20 Years
ALL
No
Sponsors
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Seoul St. Mary's Hospital
OTHER
Responsible Party
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Ho-Joong Youn
Professor
Principal Investigators
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Ho-Joong Youn, MD
Role: PRINCIPAL_INVESTIGATOR
Seoul St. Mary's Hospital
Central Contacts
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Other Identifiers
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NAFAS
Identifier Type: -
Identifier Source: org_study_id
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