Clinical Trials
Showing trials with last updates posted in 2025.
672
Participants
Multi-Arm Multi-Stage Adaptive Platform Trial (APT) for the Acute Treatment of Traumatic Brain Injury
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-08-01
Completion:
2028-08-31
Conditions
Traumatic Brain Injury
Interventions
DRUG
No Results Yet
67
Participants
The HistoSonics Edison™ System for Treatment of Primary Solid Renal Tumors Using Histotripsy (#HOPE4KIDNEY)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-01-04
Completion:
2025-09-04
Conditions
Renal Cancer
Tumor, Solid
Kidney Cancer
Tumor
Tumor, Benign
Interventions
DEVICE
No Results Yet
300
Participants
Phase 2b/3 Study to Assess ABP-671 a Novel URAT1 Inhibitor in Participants With Gout
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-08-11
Completion:
2025-01-30
Conditions
Gout
Interventions
DRUG
OTHER
No Results Yet
300
Participants
Selenoproteins as Prognostic Markers and Therapeutic Targets in Breast Cancer.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2022-05-19
Completion:
2027-11-19
Conditions
Breast Cancer
No Results Yet
50
Participants
Novel Delivery Method of Transgender Voice Therapy Using a Mobile Application
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2026-12-31
Completion:
2027-12-31
Conditions
Transitioning Voice of Transgender and Gender Diverse People
Interventions
OTHER
No Results Yet
37
Participants
Study to Explore the Safety, Tolerability, and Pharmacokinetics of AMG 305 in Subjects With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-06-13
Completion:
2026-04-10
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
40
Participants
A Nasal Treatment for COVID-19
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-06-27
Completion:
2026-03-30
Conditions
COVID-19
Healthy
Interventions
DRUG
No Results Yet
428
Participants
A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-08-08
Completion:
2026-08-31
Conditions
Primary IgA Nephropathy
Interventions
DRUG
No Results Yet
83
Participants
Study of Belantamab Mafodotin With Carfilzomib, Pomalidomide, and Dexamethasone in Relapsed Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-05-30
Completion:
2028-07-01
Conditions
Multiple Myeloma
Relapse Multiple Myeloma
Interventions
DRUG
No Results Yet
350
Participants
STEMI Treated With a Polymer-free Sirolimus-coated Stent and P2Y12 Inhibitor-based SAPT Versus Conventional DAPT
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-11-01
Completion:
2027-03-01
Conditions
ST Elevation Myocardial Infarction
Interventions
DEVICE
No Results Yet
117
Participants
Energy Metabolism Profiles Over Weight-loss and Eating Responses
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-03-02
Completion:
2025-03-01
Conditions
Homeostasis
Metabolism and Nutrition Disorder
Healthy
Obesity
Interventions
BEHAVIORAL
No Results Yet
200
Participants
Iltamiocel Compared to Placebo for Chronic Fecal Incontinence in Females With Obstetric Injury
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-03-21
Completion:
2026-12-31
Conditions
Fecal Incontinence
Interventions
BIOLOGICAL
OTHER
No Results Yet
4300
Participants
A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-03-31
Completion:
2027-04-20
Conditions
Breast Cancer, Early Breast Cancer
Interventions
DRUG
No Results Yet
51
Participants
Biofeedback vs Laryngeal Control Therapy in Management of Paradoxical Vocal Fold Motion
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-03-07
Completion:
2024-06-30
Conditions
Paradoxical Vocal Fold Motion
Vocal Cord Dysfunction
Interventions
BEHAVIORAL
No Results Yet
87
Participants
High-intensity Interval Exercise in Rheumatoid Arthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2021-08-16
Completion:
2023-06-30
Conditions
Rheumatoid Arthritis
Interventions
BEHAVIORAL
No Results Yet
381
Participants
Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-03-22
Completion:
2025-09-10
Conditions
Polymyalgia Rheumatica
Interventions
DRUG
OTHER
No Results Yet
78
Participants
A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-01-08
Completion:
2027-12-31
Conditions
Recurrent Acute Leukemia of Ambiguous Lineage
Recurrent Acute Lymphoblastic Leukemia
Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage
Recurrent Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged
Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Mixed Phenotype Acute Leukemia
Recurrent Mixed Phenotype Acute Leukemia
Refractory Acute Leukemia of Ambiguous Lineage
Refractory Acute Lymphoblastic Leukemia
Refractory Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage
Refractory Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged
Refractory Acute Myeloid Leukemia Due to Lineage Switch From Mixed Phenotype Acute Leukemia
Refractory Mixed Phenotype Acute Leukemia
Interventions
PROCEDURE
DRUG
No Results Yet
150
Participants
Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-01-10
Completion:
2027-12-10
Conditions
Amyloidosis
Transthyretin Amyloidosis
Interventions
DIAGNOSTIC_TEST
No Results Yet
286
Participants
Sleep Quality After Cesarean Delivery
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2023-03-14
Completion:
2024-05-15
Conditions
Cesarean Section Complications
Sleep Disturbance
Perioperative Complication
No Results Yet
14194
Participants
A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-04-07
Completion:
2026-09-07
Conditions
Acute Coronary Syndrome
Interventions
DRUG
OTHER
No Results Yet
90
Participants
Pharmacokinetic Study of IV Artesunate to Treat Children With Severe Malaria
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-11-29
Completion:
2025-04-01
Conditions
Plasmodium Falciparum Infection
Interventions
DRUG
No Results Yet
28
Participants
Refinement and Adaption of Reinforcement Learning to Personalize Behavioral Messaging for Healthy Habits
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-08-23
Completion:
2025-12-17
Conditions
Diabetes Mellitus, Type 2
Medication Adherence
Interventions
BEHAVIORAL
No Results Yet
110
Participants
A Clinical Study to Evaluate the Effects of Akkermansia Muciniphila and Berberine on Prediabetes Among Obese Subjects.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-03-12
Completion:
2025-06-30
Conditions
Prediabetes
Interventions
DRUG
No Results Yet
400
Participants
A Study to Follow Patients With Adult Growth Hormone Deficiency (AGHD) Treated With Sogroya® for Long Term Safety Information
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2023-02-03
Completion:
2032-12-15
Conditions
Adult Growth Hormone Deficiency
Interventions
DRUG
No Results Yet
105
Participants
A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-07-11
Completion:
2029-06-30
Conditions
Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm
Interventions
PROCEDURE
DRUG
No Results Yet
40
Participants
Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2023-04-17
Completion:
2026-08-31
Conditions
Juvenile Huntington Disease
Juvenile-Onset Huntington Disease
No Results Yet
230
Participants
A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2023-08-18
Completion:
2028-10-01
Conditions
Cardiovascular Disorder
Clonal Hematopoiesis
Hodgkin Lymphoma
Interventions
PROCEDURE
OTHER
No Results Yet
110
Participants
The Effect of the Education Given to Nursing Students With Web 2.0 Tools on the Level of Participation, Attitude, Interest and Motivation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-10-18
Completion:
2023-01-15
Conditions
Educational Problems
Interventions
BEHAVIORAL
No Results Yet
330
Participants
A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2023-11-30
Completion:
2029-06-30
Conditions
B Acute Lymphoblastic Leukemia Associated With Down Syndrome
Down Syndrome
Myeloid Leukemia Associated With Down Syndrome
Interventions
PROCEDURE
OTHER
No Results Yet
130
Participants
Evaluation of Milk Polar Lipids in Dyslipidemic Adults With Abdominal Obesity
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-10-20
Completion:
2026-05-31
Conditions
Dyslipidemias
Obesity
Interventions
DRUG
DIETARY_SUPPLEMENT
No Results Yet
1018
Participants
Ribociclib Real-world Treatment Patterns and Clinical Outcomes Among Women With HR+/HER2- Advanced or Metastatic Breast Cancer in France
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2022-12-13
Completion:
2028-06-30
Conditions
Breast Cancer
Interventions
OTHER
No Results Yet
158
Participants
Long-Term Assessment of the Safety and Performance of the NuVasive Simplify Disc at Two Levels
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2023-01-18
Completion:
2029-02-10
Conditions
Cervical Disc Disease
Degenerative Disc Disease
Interventions
DEVICE
No Results Yet
295
Participants
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-08-23
Completion:
2026-06-30
Conditions
Heart Failure
Cardiorenal Syndrome
Cardio-Renal Syndrome
ADHF
Heart Failure, Systolic
Heart Failure, Diastolic
Heart Failure; With Decompensation
Heart Failure, Congestive
Interventions
DEVICE
No Results Yet
156
Participants
A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-12-27
Completion:
2027-08-10
Conditions
Healthy Volunteers
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Interventions
DRUG
No Results Yet
246
Participants
Esketamine-propofol Versus Propofol for Flexible Bronchoscopy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-12-07
Completion:
2023-12-18
Conditions
Postoperative Recovery
Interventions
DRUG
No Results Yet
73
Participants
Functional Near-Infrared Spectroscopy (fNIRS) Combined With Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical Controls
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2023-01-23
Completion:
2024-10-10
Conditions
Juvenile Neuronal Ceroid Lipofuscinosis
Smith-Lemli-Opitz Syndrome
Creatine Transporter Deficiency
Niemann-Pick Disease Type C1
No Results Yet
280
Participants
Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 2)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-04-21
Completion:
2027-04-23
Conditions
Systemic Lupus Erythematosus
Interventions
DRUG
No Results Yet
1650
Participants
Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-01-01
Completion:
2029-05-01
Conditions
Pain, Chronic
Lupus
Pelvic Pain
Interventions
BEHAVIORAL
No Results Yet
276
Participants
Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-04-18
Completion:
2026-08-31
Conditions
Endometrial Cancer
Interventions
DRUG
No Results Yet
440
Participants
Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-08-24
Completion:
2028-06-30
Conditions
B Acute Lymphoblastic Leukemia
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
B Acute Lymphoblastic Leukemia, BCR-ABL1-Like
Lymphoblastic Lymphoma
Mixed Phenotype Acute Leukemia
T Acute Lymphoblastic Leukemia
Interventions
PROCEDURE
DRUG
DIETARY_SUPPLEMENT
OTHER
No Results Yet
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