Clinical Trials
Showing trials with last updates posted in 2025.
295
Participants
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-08-23
Completion:
2026-06-30
Conditions
Heart Failure
Cardiorenal Syndrome
Cardio-Renal Syndrome
ADHF
Heart Failure, Systolic
Heart Failure, Diastolic
Heart Failure; With Decompensation
Heart Failure, Congestive
Interventions
DEVICE
No Results Yet
156
Participants
A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-12-27
Completion:
2027-08-10
Conditions
Healthy Volunteers
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Interventions
DRUG
No Results Yet
246
Participants
Esketamine-propofol Versus Propofol for Flexible Bronchoscopy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-12-07
Completion:
2023-12-18
Conditions
Postoperative Recovery
Interventions
DRUG
No Results Yet
73
Participants
Functional Near-Infrared Spectroscopy (fNIRS) Combined With Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical Controls
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2023-01-23
Completion:
2024-10-10
Conditions
Juvenile Neuronal Ceroid Lipofuscinosis
Smith-Lemli-Opitz Syndrome
Creatine Transporter Deficiency
Niemann-Pick Disease Type C1
No Results Yet
280
Participants
Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 2)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-04-21
Completion:
2027-04-23
Conditions
Systemic Lupus Erythematosus
Interventions
DRUG
No Results Yet
1650
Participants
Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-01-01
Completion:
2029-05-01
Conditions
Pain, Chronic
Lupus
Pelvic Pain
Interventions
BEHAVIORAL
No Results Yet
276
Participants
Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-04-18
Completion:
2026-08-31
Conditions
Endometrial Cancer
Interventions
DRUG
No Results Yet
440
Participants
Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-08-24
Completion:
2028-06-30
Conditions
B Acute Lymphoblastic Leukemia
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
B Acute Lymphoblastic Leukemia, BCR-ABL1-Like
Lymphoblastic Lymphoma
Mixed Phenotype Acute Leukemia
T Acute Lymphoblastic Leukemia
Interventions
PROCEDURE
DRUG
DIETARY_SUPPLEMENT
OTHER
No Results Yet
146
Participants
Patients At Risk for Sensory Screening (HPARSS) to Enhance Sensory Deficit Screening in Childhood Cancer Survivors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-08-02
Completion:
2026-05-31
Conditions
Childhood Cancer
Interventions
OTHER
No Results Yet
450
Participants
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-10-20
Completion:
2027-02-28
Conditions
Locally Advanced or Metastatic Solid Tumors
NSCLC
HNSCC
Melanoma
TNBC
Esophageal Cancer
Gastric Cancer
Cervical Cancer
Colorectal Cancer
Urothelial Carcinoma
Clear Cell RCC
HCC
Interventions
DRUG
No Results Yet
225
Participants
Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-03-13
Completion:
2027-02-01
Conditions
Herpes Zoster
Interventions
BIOLOGICAL
No Results Yet
20
Participants
Assessment of the Efficacy and Safety of Alpelisib (BYL719) in Pediatric and Adult Patients With Megalencephaly-CApillary Malformation Polymicrogyria Syndrome (MCAP)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-11-28
Completion:
2027-03-31
Conditions
Megalencephaly-capillary Malformation Polymicrogyria Syndrome (MCAP)
Interventions
DRUG
PROCEDURE
No Results Yet
150
Participants
Otoferlin Gene-mediated Hearing Loss Natural History Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2022-07-14
Completion:
2029-02-28
Conditions
Sensorineural Hearing Loss, Bilateral
Interventions
OTHER
No Results Yet
40
Participants
Deucravacitinib Adherence Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-07-24
Completion:
2026-03-31
Conditions
Psoriasis
Interventions
BEHAVIORAL
No Results Yet
30
Participants
Depression, Aging, Stress and Heart Health Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-11-16
Completion:
2026-06-30
Conditions
Menopause
Depression
Heart Disease in Women
Stress
Interventions
BEHAVIORAL
No Results Yet
840
Participants
Evaluation of the Superiority of VAsopressin Versus NOradrenaline in the Management of Patients at Risk of Kidney Failure Undergoing Cardiac Surgery With Extracorporeal Circulation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-01-02
Completion:
2026-03-31
Conditions
Scheduled Cardiac Surgery With Extracorporeal Circulation
Vasoplegic Syndrome
Interventions
DRUG
OTHER
No Results Yet
123
Participants
Retrospective Modulus ALIF Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2022-08-18
Completion:
2022-10-15
Conditions
Degenerative Disc Disease
Spondylolisthesis
Stenosis
Interventions
DEVICE
No Results Yet
123
Participants
Effect of Oral Nutritional Supplements to Older Patients Discharged With a Rehabilitation Plan
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-12-01
Completion:
2026-03-30
Conditions
Nutritional Risk
Rehabilitation
Oral Nutritional Supplements
Interventions
DIETARY_SUPPLEMENT
No Results Yet
34
Participants
Study of BD Sirolimus Drug Coated Catheter for Treatment of Femoropopliteal Arteries
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-08-02
Completion:
2024-06-12
Conditions
Peripheral Arterial Disease
Peripheral Artery Disease
Stenosis Artery
Interventions
DEVICE
No Results Yet
150
Participants
Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-06-01
Completion:
2026-06-01
Conditions
Stress, Psychological
Racism
Discrimination, Racial
Inflammation
Pregnancy Related
Pregnancy Complications
Pregnancy, High Risk
Depression
Depression, Postpartum
Perinatal Depression
Anxiety
Anxiety in Pregnancy
Interventions
DEVICE
No Results Yet
120
Participants
Safety and Immune Responses After Vaccination With Two Investigational RNA-based Vaccines Against Tuberculosis in Healthy Volunteers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-04-18
Completion:
2025-06-06
Conditions
Tuberculosis
Interventions
BIOLOGICAL
OTHER
No Results Yet
38
Participants
BrainWeighve App Feasibility Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-11-01
Completion:
2026-12-31
Conditions
Weight Loss
Obesity and Overweight
Interventions
BEHAVIORAL
No Results Yet
1753
Participants
Lung Volume Preservation During Extubation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-01-15
Completion:
2024-08-13
Conditions
Weaning Failure
Pulmonary Collapse
Interventions
OTHER
No Results Yet
134
Participants
Evaluation of the Value of Perianal Infiltration During Thermodestruction of Haemorrhoidal Disease by Radiofrequency
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-01-10
Completion:
2025-12-16
Conditions
Hemorrhoids
Interventions
DRUG
OTHER
No Results Yet
41
Participants
A Study to Assess the Safety and Tolerability of RC88 for Patients With Advanced Solid Tumours
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-01-30
Completion:
2025-11-26
Conditions
Advanced Solid Tumours
Interventions
DRUG
No Results Yet
64
Participants
An Immediate Functional Progression Program for Adolescent Athletes With Spondylolysis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-08-22
Completion:
2025-07-01
Conditions
Lumbar Spondylosis
Interventions
OTHER
No Results Yet
150
Participants
Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2022-04-18
Completion:
2026-04-30
Conditions
Fluid Overload
Glomerulosclerosis, Focal Segmental
Edema
Membranous Nephropathy
Minimal Change Disease
Minimal Change Nephrotic Syndrome
IgM Nephropathy
Nephrotic Syndrome
Glomerular Disease
Nephrotic Syndrome, Minimal Change
Nephrotic Syndrome in Children
Nephrotic Syndrome With Edema (Diagnosis)
FSGS
Interventions
BEHAVIORAL
No Results Yet
144
Participants
Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Open Label
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-03-12
Completion:
2027-09-30
Conditions
Autism Spectrum Disorder
Interventions
DRUG
No Results Yet
34
Participants
High Intensity His Bundle Pacing in Heart Failure Patients With Narrow QRS Outcome Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-03-29
Completion:
2026-02-28
Conditions
Cardiac Conduction System
His Bundle Pacing
Heart Failure
Cardiomyopathies
Interventions
DEVICE
No Results Yet
90
Participants
Evaluation of the Implementation of a Parenting Program in Parents With Children Aged 4 to 12 Years and One Parent With an Alcohol Use Disorders
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-02-22
Completion:
2026-02-22
Conditions
Addiction, Alcohol
Interventions
OTHER
No Results Yet
2310
Participants
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-10-21
Completion:
2029-08-30
Conditions
Atherosclerotic Cardiovascular Disease
End Stage Kidney Disease
Atherosclerotic Cardiovascular Disease in Patients With ESKD
Interventions
DRUG
No Results Yet
39
Participants
Dietary Strategy to Tackle Sarcopenia in Early Elderly Subjects (FOOP-Sarc)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-09-01
Completion:
2023-05-31
Conditions
Sarcopenia
Interventions
DIETARY_SUPPLEMENT
OTHER
No Results Yet
300
Participants
Comparison of EVAR and ESAR for Infrarenal Aortic Aneurysms With a Wide Proximal Neck
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-05-26
Completion:
2029-04-30
Conditions
Aortic Aneurysm, Abdominal
Interventions
DEVICE
No Results Yet
6000
Participants
A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2022-11-21
Completion:
2027-03-31
Conditions
Neovascular Age-related Macular Degeneration
Diabetic Macular Edema
Retinal Vein Occlusion
Branch Retinal Vein Occlusion
Central Retinal Vein Occlusion
Hemi-retinal Vein Occlusion
Interventions
DRUG
COMBINATION_PRODUCT
No Results Yet
70
Participants
PAIN (Pain AI iNtervention) Platform for Patients at Home
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2022-11-23
Completion:
2026-11-30
Conditions
Pain
Interventions
OTHER
No Results Yet
200
Participants
Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-09-13
Completion:
2028-08-31
Conditions
Locoregional Recurrence
Hormone Receptor-positive Breast Cancer
HER2-negative Breast Cancer
Interventions
DRUG
No Results Yet
95
Participants
Traumatic Brain Injury and Alzheimer's Disease/Related Dementias Caregiver Support Intervention
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-07-01
Completion:
2025-06-28
Conditions
Caregiver Burden
Caregiver Stress Syndrome
Caregiver Burnout
Interventions
OTHER
No Results Yet
435
Participants
Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-03-15
Completion:
2026-06-30
Conditions
Acute Lymphoblastic Leukemia
Acute Myeloid Leukemia
Mixed Phenotype Acute Leukemia
Myelodysplastic Syndrome
Interventions
PROCEDURE
DRUG
BIOLOGICAL
OTHER
RADIATION
No Results Yet
72
Participants
A Phase 1b/2 Trial of the Safety and Microbiological Activity of Bacteriophage Therapy in Cystic Fibrosis Subjects Colonized With Pseudomonas Aeruginosa
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-10-03
Completion:
2025-04-10
Conditions
Bacterial Disease Carrier
Cystic Fibrosis
Interventions
OTHER
BIOLOGICAL
No Results Yet
52
Participants
Circadian Influence on Prolonged Exposure Therapy for PTSD
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-07-01
Completion:
2025-08-01
Conditions
PTSD
Interventions
BEHAVIORAL
No Results Yet
Showing 40 trials per page